127 ]. 1996. Elsevier." width="100%" height="100%">
Journal: Molecules
Article Title: Bicyclo[3.2.0]carbocyclic Molecules and Redox Biotransformations: The Evolution of Closed-Loop Artificial Linear Biocatalytic Cascades and Related Redox-Neutral Systems
doi: 10.3390/molecules28217249
Figure Lengend Snippet: Bioreduction by growing cultures of various yeasts and fungi of ( rac )-bicyclo[3.2.0]hept-2-en-6-one (ketone 1), ( rac )-4-methylbicyclo[3.2.0]hept-2-en-6-one (ketone 2), ( rac )-1-methylbicyclo[3.2.0]hept-2-en-6-one (ketone 3), and ( rac )-1,4-dimethylbicyclo[3.2.0]hept-2-en-6-one (ketone 4). Adapted with permission from [ 127 ]. 1996. Elsevier.
Article Snippet: Interesting in this respect is that while S. cerevisiae RM9, like the commercial bakers’ yeast strain studied previously by Glaxo Group Research, bioreduced the unsubstituted ( rac )-bicyclic ketone to principally the (+)-( 1S , 5R , 6S )- endo -alcohol, two of the other tested yeast strains (RM1 and ML31) produced the corresponding (-)-( 1R , 5S , 6R ) enantiomer as the principal bioreduction product.
Techniques: