podofilox (MedChemExpress)


Structured Review

Podofilox, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/podofilox/product/MedChemExpress
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Podofilox suppresses gastric cancer cell proliferation by regulating cell cycle arrest and the c-Myc/ATG10 axis"
Article Title: Podofilox suppresses gastric cancer cell proliferation by regulating cell cycle arrest and the c-Myc/ATG10 axis
Journal: Experimental and Therapeutic Medicine
doi: 10.3892/etm.2021.10637

Figure Legend Snippet: Microarray analysis of dysregulated genes following treatment with podofilox. (A) Heatmap of dysregulated genes in AGS cells treated with vehicle or podofilox. A total of 566 genes were upregulated, and 713 genes were downregulated. Green, downregulated genes; red, upregulated genes. (B) KEGG and HALLMARK pathway enrichment analyses of cell cycle, c-Myc and p53 signaling pathways. KEGG, Kyoto Encyclopedia of Genes and Genomes.
Techniques Used: Microarray

Figure Legend Snippet: Podofilox inhibits the proliferation of HGC-27 and AGS cells. (A and B) Cell viability was assessed in (A) AGS and (B) HGC-27 cells following incubation with podofilox (0-80 nM) for 48 h. (C and D) Cell proliferation curve was analyzed following incubation with vehicle or 3.4 nM podofilox at the indicated time points. * P
Techniques Used: Incubation

Figure Legend Snippet: Western blot analysis of dysregulated genes following treatment with podofilox. Immunoblots of HK2, PKM2, p53, c-Myc, ATG10 and GAPDH following incubation with vehicle or 3.4 nM podofilox for 48 h are presented on the left, and the quantitative analysis is presented on the right. * P
Techniques Used: Western Blot, Incubation

Figure Legend Snippet: Podofilox inhibits cell cycle progression of HGC-27 and AGS cells. (A and B) The cell cycle was analyzed in (A) AGS and (B) HGC-27 cells following incubation with vehicle or 3.4 nM podofilox for 48 h. Left, representative images; right, quantification analysis. * P
Techniques Used: Incubation

Figure Legend Snippet: Podofilox inhibits cell colony formation. (A) AGS and (B) HGC-27 cells were incubated with vehicle or 3.4 nM podofilox for 7 days, and cell colony formation was assessed. ** P
Techniques Used: Incubation