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materials availability mycoplasma pneumoniae strain m129 b7  (ATCC)


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    ATCC materials availability mycoplasma pneumoniae strain m129 b7
    Materials Availability Mycoplasma Pneumoniae Strain M129 B7, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 231 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pneumoniae/Mycoplasmoides+pneumoniae+(Somerson+et+al%2E)+Gupta+et+al/pm42790420-219-0-9
    Average 96 stars, based on 231 article reviews
    materials availability mycoplasma pneumoniae strain m129 b7 - by Bioz Stars, 2026-10
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    Activity Assay:

    Article Title: High polyketide synthase gene expression boosts pathogenicity of Klebsiella pneumoniae in the digestive infection
    Article Snippet: .. It also specifically binds to its receptor SecACellular ocesses nd sig alingIntracellular rafficki g, secreti n, and vesicular transport02024::Quorum sensing||03070::B cterial s c tion syste ||03060::Protein exportCyt plasm A6TG36 A6TG36 9037300 7486300 8479700 8794400 A6TG36 ATP synthase subunit beta OS=Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) OX=272620 GN=atpD PE=3 SV=1GO:0045261::proton-transporting ATP synthase complex, cat lytic core F(1);GO: 005886::plasma membraneGO:0046933::proton-transporting ATP sy thase activity, rotational mechanism;GO:0005524::ATP bindingGO:0015991::ATP hydrolysis coupled proton transport;GO:0042777::plasma membrane ATP synthesis coupled proton transportProduces ATP fr ADP i the p esence of a proto gradient cross the membrane. ..

    Article Title: Chlorobactine A, a Dimeric Dichlorated Metabolite from Marine-Derived Streptomyces thermolineatus NAK03196.
    Article Snippet: Using the one strain many compounds (OSMAC) strategy and guided by LC−MS results, we explored the metabolites of marine algaederived strain Streptomyces thermolineatus NAK03196 and discovered a new class of molecules with an unexpected skeleton, chlorobactine A (1).. Its structure was determined by 1D and 2D NMR spectroscopy, HR-ESI−MS, single-crystal X-ray diffraction analysis (Cu Kα), and ECD calculation.. Chlorobactine A (1) contains dichlorine atoms and possesses a unique [6/ 6/6] tricyclic fused skeleton structure.

    Membrane:

    Article Title: High polyketide synthase gene expression boosts pathogenicity of Klebsiella pneumoniae in the digestive infection
    Article Snippet: .. It also specifically binds to its receptor SecACellular ocesses nd sig alingIntracellular rafficki g, secreti n, and vesicular transport02024::Quorum sensing||03070::B cterial s c tion syste ||03060::Protein exportCyt plasm A6TG36 A6TG36 9037300 7486300 8479700 8794400 A6TG36 ATP synthase subunit beta OS=Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) OX=272620 GN=atpD PE=3 SV=1GO:0045261::proton-transporting ATP synthase complex, cat lytic core F(1);GO: 005886::plasma membraneGO:0046933::proton-transporting ATP sy thase activity, rotational mechanism;GO:0005524::ATP bindingGO:0015991::ATP hydrolysis coupled proton transport;GO:0042777::plasma membrane ATP synthesis coupled proton transportProduces ATP fr ADP i the p esence of a proto gradient cross the membrane. ..

    Synthesized:

    Article Title: High polyketide synthase gene expression boosts pathogenicity of Klebsiella pneumoniae in the digestive infection
    Article Snippet: .. Probably not involved in DNA repairI formation storage a d processingTra scriptionNA Cytoplasm A6THM6 A6THM6 93070 40901 23503 85300 A6THM6 Helicase C-terminal domain-containing protein OS=Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) OX=272620 GN=KPN_04710 PE=4 SV=1NA GO:0004386::helicase activityNA Helicase con erved C-terminal domainI formation st rag and roc ssingTranscripti nNA Cytopla m A7M6Y1 A7M6Y1 14837 11852 41363 16280 A7M6Y1 Glycosyl transferase, group 1 family OS=Klebsiella pneumoniae OX=573 GN=wckW PE=4 SV=1NA NA NA Glycosyltransferase, group 1 family proteinCellular processes nd signalingC ll wall/ embr ne/envelope biogenesis01100::Metabolic pathways||00500::Starch and sucrose metabolismCytoplasm A7M6Y7 A7M6Y7 89623 66714 415790 81461 A7M6Y7 6-phosphogluconate dehydrogenase, decarboxylating OS=Klebsiella pneumoniae OX=573 GN=gnd PE=3 SV=1NA GO:0004616::phosphogluconate dehydrogenase (decarboxylating) activityGO:0019521::D-gluconate metabolic process;GO:0006098::pentose-phosphate shunt;GO:0055114::oxidation-reduction processCata yzes th oxidative d carboxylation of 6- phosphogluconate to rib lose 5-phosphate and CO(2), wi h concomitant reduction of NADP to NADPHMetab li mCo zy e tr nsp rt and metabolism0110 ::Metabolic athways||01110::Biosynthesis f secondary metaboli es||01120::Microbial metabolism in diverse environments||01130::Biosynthesis of antibiotics||01200::Carbon metabolism||00030::Pentose phosphate pathway||00480::Glutathione metabolismCy oplasm B5RKB3 B5RKB3 1633100 2305800 1715000 1654700 B5RKB3 Tellurium resistance protein TerE OS=Klebsiella pneumoniae (strain 342) OX=507522 GN=terE PE=4 SV=1NA NA GO:0046690::response to tellu ium ion;GO:00 6950::response to stressTe D d aiCellular processes and signalingSignal transductio mechanismNA Ext acellular B5XN78 B5XN78 1184800 1246500 1265300 1189600 B5XN78 Peptidyl-prolyl cis-trans isomerase OS=Klebsiella pneumoniae (strain 342) OX=507522 GN=slyD PE=3 SV=1NA NA NA P ptidyl-prolyl cis-transMetabolismCarbohydrate transport and metabolismNA Cytoplasm B5XNC4 B5XNC4 729260 323640 194580 211580 B5XNC4 Peptide deformylase OS=Klebsiella pneumoniae (strain 342) OX=507522 GN=def PE=3 SV=1NA GO:0005506::iron ion b nding;GO:0042586::peptide deformylase activityGO:0006412::tra sl tionRemoves the formyl group from th N-t rminal Met of newly synthesized proteins. ..

    Diffusion-based Assay:

    Article Title: Screening, isolation, identification and evaluation of bacteria with probiotic potential from traditional palmyra palm nectar
    Article Snippet: .. The antimicrobial potential of the probiotic isolates was analysed against selected enteric pathogens, including S. flexneri (ATCC 12022), S . sonnei (ATCC 25931), S. Typhi (MTCC 733), K . pneumoniae (ATCC 700603), and E. coli (ATCC 49106), using well diffusion technique with slight changes from the method outlined by Gunyakti et al ( ). ..

    Bacteria:

    Article Title: Chlorobactine A, a Dimeric Dichlorated Metabolite from Marine-Derived Streptomyces thermolineatus NAK03196.
    Article Snippet: Using the one strain many compounds (OSMAC) strategy and guided by LC−MS results, we explored the metabolites of marine algaederived strain Streptomyces thermolineatus NAK03196 and discovered a new class of molecules with an unexpected skeleton, chlorobactine A (1).. Its structure was determined by 1D and 2D NMR spectroscopy, HR-ESI−MS, single-crystal X-ray diffraction analysis (Cu Kα), and ECD calculation.. Chlorobactine A (1) contains dichlorine atoms and possesses a unique [6/ 6/6] tricyclic fused skeleton structure.



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    (A–B) Serum killing kinetics of Kp38088 in normal human serum. Kp38088 survival was monitored over time following incubation with 25%, 50%, or 75% NHS. Heat-inactivated serum was used as a negative control. Bacteria were inoculated at 1 × 10 4 CFU (A) or 1 × 10 6 CFU (B). Kp38088 exhibited resistance to complement-mediated killing at a higher inoculum, Kp38088 remained resistant to killing by 25% and 50% NHS after extended incubation (6–12 h), demonstrating a dose-dependent capacity to withstand serum-mediated antibacterial activity. (C–D) Species-dependent differences in serum-mediated killing of Kp38088. Kp38088 survival was assessed following incubation with normal sera from human serum (H) and C57BL/6 mouse serum (M), at the indicated concentrations. Bacterial survival was determined using an initial inoculum of 1 × 10 4 CFU (C) or 1 × 10 6 CFU (D). Mouse sera showed limited antibacterial activity against Kp38088 at both inoculum levels, whereas human serum exhibited substantial bactericidal activity. Notably, a high inoculum of Kp38088 displayed enhanced survival and resisted killing in 25% and 50% NHS. (E–F) Comparison of serum resistance among clinical K. pneumoniae isolates. Serum survival of different isolates, including ATCC 700603, Kp26529, Kp38088, NTUH-K2044, and ATCC 43816, was evaluated. Kp26529 and Kp38088 represent hypervirulent carbapenem-resistant K. pneumoniae (hv-CRKP) isolates, belonging to ST11-KL47 and ST11-KL64 lineages, respectively. Bacterial survival was determined in 25% NHS with an initial inoculum of 1 × 10 4 CFU (E) and in 50% NHS with 1 × 10 6 CFU respectively (F). Data were presented as the mean ± SEM of two independent experiments using five different normal human serum samples (A-B). Data were represented the means and SEM of three independent experiments (C-F).
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    (A–B) Serum killing kinetics of Kp38088 in normal human serum. Kp38088 survival was monitored over time following incubation with 25%, 50%, or 75% NHS. Heat-inactivated serum was used as a negative control. Bacteria were inoculated at 1 × 10 4 CFU (A) or 1 × 10 6 CFU (B). Kp38088 exhibited resistance to complement-mediated killing at a higher inoculum, Kp38088 remained resistant to killing by 25% and 50% NHS after extended incubation (6–12 h), demonstrating a dose-dependent capacity to withstand serum-mediated antibacterial activity. (C–D) Species-dependent differences in serum-mediated killing of Kp38088. Kp38088 survival was assessed following incubation with normal sera from human serum (H) and C57BL/6 mouse serum (M), at the indicated concentrations. Bacterial survival was determined using an initial inoculum of 1 × 10 4 CFU (C) or 1 × 10 6 CFU (D). Mouse sera showed limited antibacterial activity against Kp38088 at both inoculum levels, whereas human serum exhibited substantial bactericidal activity. Notably, a high inoculum of Kp38088 displayed enhanced survival and resisted killing in 25% and 50% NHS. (E–F) Comparison of serum resistance among clinical K. pneumoniae isolates. Serum survival of different isolates, including ATCC 700603, Kp26529, Kp38088, NTUH-K2044, and ATCC 43816, was evaluated. Kp26529 and Kp38088 represent hypervirulent carbapenem-resistant K. pneumoniae (hv-CRKP) isolates, belonging to ST11-KL47 and ST11-KL64 lineages, respectively. Bacterial survival was determined in 25% NHS with an initial inoculum of 1 × 10 4 CFU (E) and in 50% NHS with 1 × 10 6 CFU respectively (F). Data were presented as the mean ± SEM of two independent experiments using five different normal human serum samples (A-B). Data were represented the means and SEM of three independent experiments (C-F).
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    (A–B) Serum killing kinetics of Kp38088 in normal human serum. Kp38088 survival was monitored over time following incubation with 25%, 50%, or 75% NHS. Heat-inactivated serum was used as a negative control. Bacteria were inoculated at 1 × 10 4 CFU (A) or 1 × 10 6 CFU (B). Kp38088 exhibited resistance to complement-mediated killing at a higher inoculum, Kp38088 remained resistant to killing by 25% and 50% NHS after extended incubation (6–12 h), demonstrating a dose-dependent capacity to withstand serum-mediated antibacterial activity. (C–D) Species-dependent differences in serum-mediated killing of Kp38088. Kp38088 survival was assessed following incubation with normal sera from human serum (H) and C57BL/6 mouse serum (M), at the indicated concentrations. Bacterial survival was determined using an initial inoculum of 1 × 10 4 CFU (C) or 1 × 10 6 CFU (D). Mouse sera showed limited antibacterial activity against Kp38088 at both inoculum levels, whereas human serum exhibited substantial bactericidal activity. Notably, a high inoculum of Kp38088 displayed enhanced survival and resisted killing in 25% and 50% NHS. (E–F) Comparison of serum resistance among clinical K. pneumoniae isolates. Serum survival of different isolates, including ATCC 700603, Kp26529, Kp38088, NTUH-K2044, and ATCC 43816, was evaluated. Kp26529 and Kp38088 represent hypervirulent carbapenem-resistant K. pneumoniae (hv-CRKP) isolates, belonging to ST11-KL47 and ST11-KL64 lineages, respectively. Bacterial survival was determined in 25% NHS with an initial inoculum of 1 × 10 4 CFU (E) and in 50% NHS with 1 × 10 6 CFU respectively (F). Data were presented as the mean ± SEM of two independent experiments using five different normal human serum samples (A-B). Data were represented the means and SEM of three independent experiments (C-F).

    Journal: PLOS Pathogens

    Article Title: GM000287 is a conserved determinant of serum resistance and virulence in Klebsiella pneumoniae

    doi: 10.1371/journal.ppat.1014619

    Figure Lengend Snippet: (A–B) Serum killing kinetics of Kp38088 in normal human serum. Kp38088 survival was monitored over time following incubation with 25%, 50%, or 75% NHS. Heat-inactivated serum was used as a negative control. Bacteria were inoculated at 1 × 10 4 CFU (A) or 1 × 10 6 CFU (B). Kp38088 exhibited resistance to complement-mediated killing at a higher inoculum, Kp38088 remained resistant to killing by 25% and 50% NHS after extended incubation (6–12 h), demonstrating a dose-dependent capacity to withstand serum-mediated antibacterial activity. (C–D) Species-dependent differences in serum-mediated killing of Kp38088. Kp38088 survival was assessed following incubation with normal sera from human serum (H) and C57BL/6 mouse serum (M), at the indicated concentrations. Bacterial survival was determined using an initial inoculum of 1 × 10 4 CFU (C) or 1 × 10 6 CFU (D). Mouse sera showed limited antibacterial activity against Kp38088 at both inoculum levels, whereas human serum exhibited substantial bactericidal activity. Notably, a high inoculum of Kp38088 displayed enhanced survival and resisted killing in 25% and 50% NHS. (E–F) Comparison of serum resistance among clinical K. pneumoniae isolates. Serum survival of different isolates, including ATCC 700603, Kp26529, Kp38088, NTUH-K2044, and ATCC 43816, was evaluated. Kp26529 and Kp38088 represent hypervirulent carbapenem-resistant K. pneumoniae (hv-CRKP) isolates, belonging to ST11-KL47 and ST11-KL64 lineages, respectively. Bacterial survival was determined in 25% NHS with an initial inoculum of 1 × 10 4 CFU (E) and in 50% NHS with 1 × 10 6 CFU respectively (F). Data were presented as the mean ± SEM of two independent experiments using five different normal human serum samples (A-B). Data were represented the means and SEM of three independent experiments (C-F).

    Article Snippet: We compared the survival of five representative strains, including ATCC 700603, Kp26529, Kp38088, NTUH-K2044, and the well-studied Kp strain ATCC 43816.

    Techniques: Incubation, Negative Control, Bacteria, Activity Assay, Comparison, Blood/Plasma/Serum Samples

    (A–B) Conservation analysis of GM000287 among Klebsiella species and the Enterobacteriaceae family. The prevalence of GM000287 was calculated as the proportion of GM000287-positive strains within each species. Panel (A) included 326 Klebsiella strains, and panel (B) included 143 representativ e Enterobacteriaceae strains. The number of strains analyzed for each species was listed at the right of each bar. Average sequence identity represents the mean amino acid sequence identity among GM000287-positive strains within each species. (C–D) GM000287 contributes to serum resistance in multiple Kp strains. Wild-type strains (ATCC 43816, Kp26529, and Kp39468) and their corresponding ΔGM000287 mutants were incubated with NHS using an inoculum of 1 × 10 4 CFU (C) or 1 × 10 6 CFU (D), followed by CFU enumeration. Data were represented the means ± SEM from two independent experiments. Statistical significance was determined using unpaired two-tailed Student’s t-test. **, P < 0.01; *, P < 0.05; ns, not significant (5C and 5D).

    Journal: PLOS Pathogens

    Article Title: GM000287 is a conserved determinant of serum resistance and virulence in Klebsiella pneumoniae

    doi: 10.1371/journal.ppat.1014619

    Figure Lengend Snippet: (A–B) Conservation analysis of GM000287 among Klebsiella species and the Enterobacteriaceae family. The prevalence of GM000287 was calculated as the proportion of GM000287-positive strains within each species. Panel (A) included 326 Klebsiella strains, and panel (B) included 143 representativ e Enterobacteriaceae strains. The number of strains analyzed for each species was listed at the right of each bar. Average sequence identity represents the mean amino acid sequence identity among GM000287-positive strains within each species. (C–D) GM000287 contributes to serum resistance in multiple Kp strains. Wild-type strains (ATCC 43816, Kp26529, and Kp39468) and their corresponding ΔGM000287 mutants were incubated with NHS using an inoculum of 1 × 10 4 CFU (C) or 1 × 10 6 CFU (D), followed by CFU enumeration. Data were represented the means ± SEM from two independent experiments. Statistical significance was determined using unpaired two-tailed Student’s t-test. **, P < 0.01; *, P < 0.05; ns, not significant (5C and 5D).

    Article Snippet: We compared the survival of five representative strains, including ATCC 700603, Kp26529, Kp38088, NTUH-K2044, and the well-studied Kp strain ATCC 43816.

    Techniques: Analysis, Sequencing, Incubation, Two Tailed Test