bidirectional flow model mimetas 2 lane organoplate  (Mimetas Inc)

Journal: Micromachines

Article Title: The Microfluidic Trainer: Design, Fabrication and Validation of a Tool for Testing and Improving Manual Skills

doi: 10.3390/mi11090872

Figure Lengend Snippet: Validation protocol. ( A ) Comparison of the inlet of the MT single tester cell (on the left) and of the commercial microfluidic plate (OrganoPlate ® 2-lane, on the right) (objective 4×); ( B ) Graph representation of the filling process of the MT device; ( C ) MT tester cells on the exercise plate that are filled with the staining solution (1.3 µL Betadine ® ), at the end of the validation test (representative image). On the top right, a magnification of representative images of one correctly filled cell (pass), and one failed cell (fail).

Article Snippet: The diameter of the inlet and the diameter of the exercise path has been defined to be as similar as possible to those of the reference microfluidic plate that has been considered in this study (OrganoPlate ® 2-lane, Mimetas, Leiden, The Netherlands).

Techniques: Staining

Journal: Micromachines

Article Title: The Microfluidic Trainer: Design, Fabrication and Validation of a Tool for Testing and Improving Manual Skills

doi: 10.3390/mi11090872

Figure Lengend Snippet: Pilot study 1. Performance of the MT device as a tester. ( A ) Correlation of success rate relative to the MT device with previous recent experience with micropipetting in the last 6 months ( n = 21, * p > 0.05, Wilcoxon correlation test); ( B ) Correlation of success rate relative to the MT device with the level of experience in handling microfluidic supports, as measured with OrganoPlate ® 2-lane ( n = 21, ** p < 0.05, Spearman correlation test). ( C ) The receiver operating characteristic (ROC) curve for the prediction ability of the MT device about the performance in handling microfluidic supports ( n = 21, * p = 0.0167, good performers n = 10, bed performers n = 11).

Article Snippet: The diameter of the inlet and the diameter of the exercise path has been defined to be as similar as possible to those of the reference microfluidic plate that has been considered in this study (OrganoPlate ® 2-lane, Mimetas, Leiden, The Netherlands).

Techniques:

Journal: Micromachines

Article Title: The Microfluidic Trainer: Design, Fabrication and Validation of a Tool for Testing and Improving Manual Skills

doi: 10.3390/mi11090872

Figure Lengend Snippet: Pilot study 2. Performance of the MT device as a trainer. Level of experience in handling microfluidic supports, as measured with OrganoPlate ® 2-lane, before (T0) and after (T1) 3 slots of 30-min continuous training with the MT device. The filled circles are relative to new users, the empty circles are relative to the experts ( n = 8, ** p < 0.005, Wilcoxon test of paired analysis).

Article Snippet: The diameter of the inlet and the diameter of the exercise path has been defined to be as similar as possible to those of the reference microfluidic plate that has been considered in this study (OrganoPlate ® 2-lane, Mimetas, Leiden, The Netherlands).

Techniques: