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klc1  (Bioss)


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    Bioss klc1
    Integrated multiomics analysis of <t>KLC1</t> . (A) SMR analysis results from the integration of lung cancer GWAS and mQTL data at the KLC1 locus. (B) SMR analysis results of lung cancer GWAS and eQTL at the KLC1 locus. (C) SMR analysis results of lung cancer GWAS and pQTL at the KLC1 locus. (D) Correlation of SNP effect sizes for KLC1 between lung cancer GWAS and QTL data (mQTL, eQTL, pQTL). cis-QTL, cis-acting quantitative trait loci; eQTL, expression quantitative trait loci; GWAS, genome-wide association study; mQTL, methylation quantitative trait loci; pQTL, protein quantitative trait loci; SMR, summary data-based Mendelian randomization; SNP, single-nucleotide polymorphism.
    Klc1, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/klc1/product/Bioss
    Average 94 stars, based on 1 article reviews
    klc1 - by Bioz Stars, 2026-02
    94/100 stars

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    1) Product Images from "Endoplasmic reticulum stress-related genes contribute to lung cancer risk: a multiomics data integration study"

    Article Title: Endoplasmic reticulum stress-related genes contribute to lung cancer risk: a multiomics data integration study

    Journal: Translational Lung Cancer Research

    doi: 10.21037/tlcr-2025-474

    Integrated multiomics analysis of KLC1 . (A) SMR analysis results from the integration of lung cancer GWAS and mQTL data at the KLC1 locus. (B) SMR analysis results of lung cancer GWAS and eQTL at the KLC1 locus. (C) SMR analysis results of lung cancer GWAS and pQTL at the KLC1 locus. (D) Correlation of SNP effect sizes for KLC1 between lung cancer GWAS and QTL data (mQTL, eQTL, pQTL). cis-QTL, cis-acting quantitative trait loci; eQTL, expression quantitative trait loci; GWAS, genome-wide association study; mQTL, methylation quantitative trait loci; pQTL, protein quantitative trait loci; SMR, summary data-based Mendelian randomization; SNP, single-nucleotide polymorphism.
    Figure Legend Snippet: Integrated multiomics analysis of KLC1 . (A) SMR analysis results from the integration of lung cancer GWAS and mQTL data at the KLC1 locus. (B) SMR analysis results of lung cancer GWAS and eQTL at the KLC1 locus. (C) SMR analysis results of lung cancer GWAS and pQTL at the KLC1 locus. (D) Correlation of SNP effect sizes for KLC1 between lung cancer GWAS and QTL data (mQTL, eQTL, pQTL). cis-QTL, cis-acting quantitative trait loci; eQTL, expression quantitative trait loci; GWAS, genome-wide association study; mQTL, methylation quantitative trait loci; pQTL, protein quantitative trait loci; SMR, summary data-based Mendelian randomization; SNP, single-nucleotide polymorphism.

    Techniques Used: Expressing, GWAS, Methylation

    Integrated multiomics analysis of BCL2L1 . (A) SMR analysis results from the integration of lung cancer GWAS and mQTL data at the BCL2L1 locus. (B) SMR analysis results of lung cancer GWAS and eQTL data at the BCL2L1 locus. (C) Correlation of SNP effect sizes for BCL2L1 between lung cancer GWAS and QTL data (mQTL, eQTL). (D) Manhattan plots displaying the SMR results for KLC1 and BCL2L1 at the multiomics level. CHR on the X-axis indicates chromosome numbers. cis-QTL, cis-acting quantitative trait loci; eQTL, expression quantitative trait loci; GWAS, genome-wide association study; mQTL, methylation quantitative trait loci; pQTL, protein quantitative trait loci; SNP, single-nucleotide polymorphism; SMR, summary data-based Mendelian randomization.
    Figure Legend Snippet: Integrated multiomics analysis of BCL2L1 . (A) SMR analysis results from the integration of lung cancer GWAS and mQTL data at the BCL2L1 locus. (B) SMR analysis results of lung cancer GWAS and eQTL data at the BCL2L1 locus. (C) Correlation of SNP effect sizes for BCL2L1 between lung cancer GWAS and QTL data (mQTL, eQTL). (D) Manhattan plots displaying the SMR results for KLC1 and BCL2L1 at the multiomics level. CHR on the X-axis indicates chromosome numbers. cis-QTL, cis-acting quantitative trait loci; eQTL, expression quantitative trait loci; GWAS, genome-wide association study; mQTL, methylation quantitative trait loci; pQTL, protein quantitative trait loci; SNP, single-nucleotide polymorphism; SMR, summary data-based Mendelian randomization.

    Techniques Used: Expressing, GWAS, Methylation

    Expression and prognostic analysis of BCL2L1 and KCL1 . (A) Differential expression analysis of KLC1 and BCL2L1 between lung cancer and normal samples. (B) Comparison of immune cell infiltration levels in the lung cancer microenvironment between high- and low-expression groups for KLC1 and BCL2L1. (C) Overall survival analysis comparing high- and low-expression groups of KLC1 and BCL2L1. (D) Immunohistochemical analyses of KLC1 in lung cancer tissue from the HPA database. ( https://www.proteinatlas.org/ENSG00000126214-KLC1/cancer/lung+cancer ). (E) Immunohistochemical staining of BCL2L1 and KLC1 in lung cancer and normal lung tissues (scale bar: 50 µm). *, P<0.05; **, P<0.01; ***, P<0.001. CI, confidence interval; HPA, Human Protein Atlas; HR, hazard ratio; CI, confident interval; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; N, normal lung tissues; T, lung cancer tissues; TPM, transcripts per million.
    Figure Legend Snippet: Expression and prognostic analysis of BCL2L1 and KCL1 . (A) Differential expression analysis of KLC1 and BCL2L1 between lung cancer and normal samples. (B) Comparison of immune cell infiltration levels in the lung cancer microenvironment between high- and low-expression groups for KLC1 and BCL2L1. (C) Overall survival analysis comparing high- and low-expression groups of KLC1 and BCL2L1. (D) Immunohistochemical analyses of KLC1 in lung cancer tissue from the HPA database. ( https://www.proteinatlas.org/ENSG00000126214-KLC1/cancer/lung+cancer ). (E) Immunohistochemical staining of BCL2L1 and KLC1 in lung cancer and normal lung tissues (scale bar: 50 µm). *, P<0.05; **, P<0.01; ***, P<0.001. CI, confidence interval; HPA, Human Protein Atlas; HR, hazard ratio; CI, confident interval; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; N, normal lung tissues; T, lung cancer tissues; TPM, transcripts per million.

    Techniques Used: Expressing, Quantitative Proteomics, Comparison, Immunohistochemical staining, Staining

    Diagram illustrating the regulatory mechanisms and functions of the ERS-related genes KLC1 and BCL2L1 in lung cancer. ERS, endoplasmic reticulum stress.
    Figure Legend Snippet: Diagram illustrating the regulatory mechanisms and functions of the ERS-related genes KLC1 and BCL2L1 in lung cancer. ERS, endoplasmic reticulum stress.

    Techniques Used:



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    klc1  (Bioss)
    94
    Bioss klc1
    Integrated multiomics analysis of <t>KLC1</t> . (A) SMR analysis results from the integration of lung cancer GWAS and mQTL data at the KLC1 locus. (B) SMR analysis results of lung cancer GWAS and eQTL at the KLC1 locus. (C) SMR analysis results of lung cancer GWAS and pQTL at the KLC1 locus. (D) Correlation of SNP effect sizes for KLC1 between lung cancer GWAS and QTL data (mQTL, eQTL, pQTL). cis-QTL, cis-acting quantitative trait loci; eQTL, expression quantitative trait loci; GWAS, genome-wide association study; mQTL, methylation quantitative trait loci; pQTL, protein quantitative trait loci; SMR, summary data-based Mendelian randomization; SNP, single-nucleotide polymorphism.
    Klc1, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/klc1/product/Bioss
    Average 94 stars, based on 1 article reviews
    klc1 - by Bioz Stars, 2026-02
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    Integrated multiomics analysis of KLC1 . (A) SMR analysis results from the integration of lung cancer GWAS and mQTL data at the KLC1 locus. (B) SMR analysis results of lung cancer GWAS and eQTL at the KLC1 locus. (C) SMR analysis results of lung cancer GWAS and pQTL at the KLC1 locus. (D) Correlation of SNP effect sizes for KLC1 between lung cancer GWAS and QTL data (mQTL, eQTL, pQTL). cis-QTL, cis-acting quantitative trait loci; eQTL, expression quantitative trait loci; GWAS, genome-wide association study; mQTL, methylation quantitative trait loci; pQTL, protein quantitative trait loci; SMR, summary data-based Mendelian randomization; SNP, single-nucleotide polymorphism.

    Journal: Translational Lung Cancer Research

    Article Title: Endoplasmic reticulum stress-related genes contribute to lung cancer risk: a multiomics data integration study

    doi: 10.21037/tlcr-2025-474

    Figure Lengend Snippet: Integrated multiomics analysis of KLC1 . (A) SMR analysis results from the integration of lung cancer GWAS and mQTL data at the KLC1 locus. (B) SMR analysis results of lung cancer GWAS and eQTL at the KLC1 locus. (C) SMR analysis results of lung cancer GWAS and pQTL at the KLC1 locus. (D) Correlation of SNP effect sizes for KLC1 between lung cancer GWAS and QTL data (mQTL, eQTL, pQTL). cis-QTL, cis-acting quantitative trait loci; eQTL, expression quantitative trait loci; GWAS, genome-wide association study; mQTL, methylation quantitative trait loci; pQTL, protein quantitative trait loci; SMR, summary data-based Mendelian randomization; SNP, single-nucleotide polymorphism.

    Article Snippet: The antibodies employed in this IHC analysis were BCL2L1 (bs-1336R; Bioss Antibodies, Woburn, MA, USA) and KLC1 (bs-11212R; Bioss Antibodies).

    Techniques: Expressing, GWAS, Methylation

    Integrated multiomics analysis of BCL2L1 . (A) SMR analysis results from the integration of lung cancer GWAS and mQTL data at the BCL2L1 locus. (B) SMR analysis results of lung cancer GWAS and eQTL data at the BCL2L1 locus. (C) Correlation of SNP effect sizes for BCL2L1 between lung cancer GWAS and QTL data (mQTL, eQTL). (D) Manhattan plots displaying the SMR results for KLC1 and BCL2L1 at the multiomics level. CHR on the X-axis indicates chromosome numbers. cis-QTL, cis-acting quantitative trait loci; eQTL, expression quantitative trait loci; GWAS, genome-wide association study; mQTL, methylation quantitative trait loci; pQTL, protein quantitative trait loci; SNP, single-nucleotide polymorphism; SMR, summary data-based Mendelian randomization.

    Journal: Translational Lung Cancer Research

    Article Title: Endoplasmic reticulum stress-related genes contribute to lung cancer risk: a multiomics data integration study

    doi: 10.21037/tlcr-2025-474

    Figure Lengend Snippet: Integrated multiomics analysis of BCL2L1 . (A) SMR analysis results from the integration of lung cancer GWAS and mQTL data at the BCL2L1 locus. (B) SMR analysis results of lung cancer GWAS and eQTL data at the BCL2L1 locus. (C) Correlation of SNP effect sizes for BCL2L1 between lung cancer GWAS and QTL data (mQTL, eQTL). (D) Manhattan plots displaying the SMR results for KLC1 and BCL2L1 at the multiomics level. CHR on the X-axis indicates chromosome numbers. cis-QTL, cis-acting quantitative trait loci; eQTL, expression quantitative trait loci; GWAS, genome-wide association study; mQTL, methylation quantitative trait loci; pQTL, protein quantitative trait loci; SNP, single-nucleotide polymorphism; SMR, summary data-based Mendelian randomization.

    Article Snippet: The antibodies employed in this IHC analysis were BCL2L1 (bs-1336R; Bioss Antibodies, Woburn, MA, USA) and KLC1 (bs-11212R; Bioss Antibodies).

    Techniques: Expressing, GWAS, Methylation

    Expression and prognostic analysis of BCL2L1 and KCL1 . (A) Differential expression analysis of KLC1 and BCL2L1 between lung cancer and normal samples. (B) Comparison of immune cell infiltration levels in the lung cancer microenvironment between high- and low-expression groups for KLC1 and BCL2L1. (C) Overall survival analysis comparing high- and low-expression groups of KLC1 and BCL2L1. (D) Immunohistochemical analyses of KLC1 in lung cancer tissue from the HPA database. ( https://www.proteinatlas.org/ENSG00000126214-KLC1/cancer/lung+cancer ). (E) Immunohistochemical staining of BCL2L1 and KLC1 in lung cancer and normal lung tissues (scale bar: 50 µm). *, P<0.05; **, P<0.01; ***, P<0.001. CI, confidence interval; HPA, Human Protein Atlas; HR, hazard ratio; CI, confident interval; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; N, normal lung tissues; T, lung cancer tissues; TPM, transcripts per million.

    Journal: Translational Lung Cancer Research

    Article Title: Endoplasmic reticulum stress-related genes contribute to lung cancer risk: a multiomics data integration study

    doi: 10.21037/tlcr-2025-474

    Figure Lengend Snippet: Expression and prognostic analysis of BCL2L1 and KCL1 . (A) Differential expression analysis of KLC1 and BCL2L1 between lung cancer and normal samples. (B) Comparison of immune cell infiltration levels in the lung cancer microenvironment between high- and low-expression groups for KLC1 and BCL2L1. (C) Overall survival analysis comparing high- and low-expression groups of KLC1 and BCL2L1. (D) Immunohistochemical analyses of KLC1 in lung cancer tissue from the HPA database. ( https://www.proteinatlas.org/ENSG00000126214-KLC1/cancer/lung+cancer ). (E) Immunohistochemical staining of BCL2L1 and KLC1 in lung cancer and normal lung tissues (scale bar: 50 µm). *, P<0.05; **, P<0.01; ***, P<0.001. CI, confidence interval; HPA, Human Protein Atlas; HR, hazard ratio; CI, confident interval; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; N, normal lung tissues; T, lung cancer tissues; TPM, transcripts per million.

    Article Snippet: The antibodies employed in this IHC analysis were BCL2L1 (bs-1336R; Bioss Antibodies, Woburn, MA, USA) and KLC1 (bs-11212R; Bioss Antibodies).

    Techniques: Expressing, Quantitative Proteomics, Comparison, Immunohistochemical staining, Staining

    Diagram illustrating the regulatory mechanisms and functions of the ERS-related genes KLC1 and BCL2L1 in lung cancer. ERS, endoplasmic reticulum stress.

    Journal: Translational Lung Cancer Research

    Article Title: Endoplasmic reticulum stress-related genes contribute to lung cancer risk: a multiomics data integration study

    doi: 10.21037/tlcr-2025-474

    Figure Lengend Snippet: Diagram illustrating the regulatory mechanisms and functions of the ERS-related genes KLC1 and BCL2L1 in lung cancer. ERS, endoplasmic reticulum stress.

    Article Snippet: The antibodies employed in this IHC analysis were BCL2L1 (bs-1336R; Bioss Antibodies, Woburn, MA, USA) and KLC1 (bs-11212R; Bioss Antibodies).

    Techniques: