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a427 cells  (ATCC)


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    ATCC a427 cells
    A427 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 378 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/a427/A-427/pm42191797-192-19-23
    Average 96 stars, based on 378 article reviews
    a427 cells - by Bioz Stars, 2026-09
    96/100 stars

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    Cell Culture:

    Article Title: Visible neural network framework
    Article Snippet: .. A549, A427, and MCF7 cells were retrieved from the American Type Culture Collection (ATCC) and cultured in DMEM: 10% FBS or EMEM+10% FBS according to ATCC recommendations. ..

    Article Title: Tricyclic compounds as inhibitors of KRAS
    Article Snippet: .. MIA PaCa-2 (KRAS G12C; ATCC® CRL-1420), NCI-H358 (KRAS G12C; ATCC® CRL-5807), A427 (KRAS G12D; ATCC® HTB53), HPAFII (KRAS G12D; ATCC® CRL-1997), YAPC (KRAS G12V; DSMZ ACC382), SW480 (KRAS G12V; ATCC® CRL-228) and NCI-H838 (KRAS WT; ATCC® CRL-5844) cells are cultured in RPMI 1640 media supplemented with 10% FBS (Gibco/Life Technologies). ..



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    Dose response inhibition of Cobimetinib and Etrasimod across KRAS mutant nonsmall cell lung cancer cell lines. A, B) Dose response curve of Cobimetinib and Etrasimod for SKLU1, A427, and A549 cells. C) Table reports IC 50 values and maximal observed inhibition ( E max ) in each condition. Curves were determined as mean of triplicates and fitted to a four-parameter logistic dose–response curve. Data are means ± SEM.

    Journal: ACS Omega

    Article Title: Machine Learning-Driven Drug Repurposing for KRAS G12C and KRAS G12D Inhibition

    doi: 10.1021/acsomega.5c12639

    Figure Lengend Snippet: Dose response inhibition of Cobimetinib and Etrasimod across KRAS mutant nonsmall cell lung cancer cell lines. A, B) Dose response curve of Cobimetinib and Etrasimod for SKLU1, A427, and A549 cells. C) Table reports IC 50 values and maximal observed inhibition ( E max ) in each condition. Curves were determined as mean of triplicates and fitted to a four-parameter logistic dose–response curve. Data are means ± SEM.

    Article Snippet: For the laboratory experiments, SKLU1 and A427 (KRAS G12D) and A549 (KRAS G12S) lung cancer cells were obtained from the American Type Culture Collection (ATCC) and maintained in standard culture conditions using basal media supplemented with 10% FCS and 1% penicillin–streptomycin.

    Techniques: Inhibition, Mutagenesis