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Serum levels of 5-HT, CCK, VIP, and MTL in mice from each group. (A) 5-HT content; (B) CCK content; (C) MTL content; (D) VIP content. Note: NC: normal control group; NM: model group; HF: Polygonatum sibiricum and Poria cocos group.

Journal: Frontiers in Pharmacology

Article Title: Polygonatum sibiricum combined with Poria cocos prevents spleen deficiency constipation via the gut microbiota–mediated brain–gut axis

doi: 10.3389/fphar.2026.1793441

Figure Lengend Snippet: Serum levels of 5-HT, CCK, VIP, and MTL in mice from each group. (A) 5-HT content; (B) CCK content; (C) MTL content; (D) VIP content. Note: NC: normal control group; NM: model group; HF: Polygonatum sibiricum and Poria cocos group.

Article Snippet: Mouse Serotonin (5-HT) ELISA Research Kit (Cat# JM-02726M2), Mouse Cholecystokinin (CCK) ELISA Research Kit (Cat# JM-02311M2), Mouse Motilin (MTL) ELISA Research Kit (Cat# JM-02775M2), Mouse Vasoactive Intestinal Peptide (VIP) ELISA Research Kit (Cat# JM-02729M2), the aforementioned kits were procured from Jiangsu Jingmei Biotechnology Co., Ltd. Superoxide Dismutase (SOD) Activity Assay Kit (BC0175), Malondialdehyde (MDA) Content Assay kit (BC0025), the aforementioned kits were procured from Beijing Solarbio Science & Technology Co., Ltd.

Techniques: Control