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satb homeobox 2 satb2  (Proteintech)


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    Proteintech satb homeobox 2 satb2
    Satb Homeobox 2 Satb2, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 15 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/satb homeobox 2 satb2/product/Proteintech
    Average 93 stars, based on 15 article reviews
    satb homeobox 2 satb2 - by Bioz Stars, 2026-03
    93/100 stars

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    Experimental design. Stable humeral fractures were established in SD rats. Biomechanical properties were assessed by three-point bending test at postoperative weeks 3 and 6. Tissue sections were prepared and subjected to HE staining and Masson staining to assess osteogenic differentiation. IHC assay was performed to assess the expression of ALP and PI3K/Akt pathway-related proteins. The expression of SATB2 and its related factors was quantified by RT-qPCR, ELISA, and western blot.

    Journal: Open Life Sciences

    Article Title: SATB2 promotes humeral fracture healing in rats by activating the PI3K/AKT pathway

    doi: 10.1515/biol-2025-1126

    Figure Lengend Snippet: Experimental design. Stable humeral fractures were established in SD rats. Biomechanical properties were assessed by three-point bending test at postoperative weeks 3 and 6. Tissue sections were prepared and subjected to HE staining and Masson staining to assess osteogenic differentiation. IHC assay was performed to assess the expression of ALP and PI3K/Akt pathway-related proteins. The expression of SATB2 and its related factors was quantified by RT-qPCR, ELISA, and western blot.

    Article Snippet: The rats were fasted for 24 h. The PI3K/AKT inhibition group and the SATB2 + PI3K/AKT inhibition group were administered with a PI3K/AKT inhibitor (PI3K/AKT-in-1, #HY-144806, MedChemExpress, USA) at 2 g/kg.

    Techniques: Staining, Expressing, Quantitative RT-PCR, Enzyme-linked Immunosorbent Assay, Western Blot

    SATB2 promotes humeral fracture healing: (a) RT-qPCR was used to detect SATB2 expression, (b) MS staining shows the degree of fracture healing, and (c) HE staining shows histological findings of bone healing. * p < 0.05 was considered statistically significant.

    Journal: Open Life Sciences

    Article Title: SATB2 promotes humeral fracture healing in rats by activating the PI3K/AKT pathway

    doi: 10.1515/biol-2025-1126

    Figure Lengend Snippet: SATB2 promotes humeral fracture healing: (a) RT-qPCR was used to detect SATB2 expression, (b) MS staining shows the degree of fracture healing, and (c) HE staining shows histological findings of bone healing. * p < 0.05 was considered statistically significant.

    Article Snippet: The rats were fasted for 24 h. The PI3K/AKT inhibition group and the SATB2 + PI3K/AKT inhibition group were administered with a PI3K/AKT inhibitor (PI3K/AKT-in-1, #HY-144806, MedChemExpress, USA) at 2 g/kg.

    Techniques: Quantitative RT-PCR, Expressing, Staining

    Overexpression of SATB2 enhances osteogenic differentiation: (a) IHC staining detected ALP; (b)–(d) western blotting detection of ALP, RANKL, and OPG. * p < 0.05 was considered statistically significant.

    Journal: Open Life Sciences

    Article Title: SATB2 promotes humeral fracture healing in rats by activating the PI3K/AKT pathway

    doi: 10.1515/biol-2025-1126

    Figure Lengend Snippet: Overexpression of SATB2 enhances osteogenic differentiation: (a) IHC staining detected ALP; (b)–(d) western blotting detection of ALP, RANKL, and OPG. * p < 0.05 was considered statistically significant.

    Article Snippet: The rats were fasted for 24 h. The PI3K/AKT inhibition group and the SATB2 + PI3K/AKT inhibition group were administered with a PI3K/AKT inhibitor (PI3K/AKT-in-1, #HY-144806, MedChemExpress, USA) at 2 g/kg.

    Techniques: Over Expression, Immunohistochemistry, Western Blot

    Effects of SATB2 on serum osteocalcin, CTX-I, BMP-2, and inflammation. (a)–(c) ELISA detected serum osteocalcin, BMP-2, and CTX-I in rats. (d) ELISA for the determination of IL-6 in rat plasma and serum. (e) ELISA for the detection of TNF-α in rat plasma and serum. (f) and (g) ELISA for plasma NO level and eNOS activity in rats. * p < 0.05 was considered statistically significant.

    Journal: Open Life Sciences

    Article Title: SATB2 promotes humeral fracture healing in rats by activating the PI3K/AKT pathway

    doi: 10.1515/biol-2025-1126

    Figure Lengend Snippet: Effects of SATB2 on serum osteocalcin, CTX-I, BMP-2, and inflammation. (a)–(c) ELISA detected serum osteocalcin, BMP-2, and CTX-I in rats. (d) ELISA for the determination of IL-6 in rat plasma and serum. (e) ELISA for the detection of TNF-α in rat plasma and serum. (f) and (g) ELISA for plasma NO level and eNOS activity in rats. * p < 0.05 was considered statistically significant.

    Article Snippet: The rats were fasted for 24 h. The PI3K/AKT inhibition group and the SATB2 + PI3K/AKT inhibition group were administered with a PI3K/AKT inhibitor (PI3K/AKT-in-1, #HY-144806, MedChemExpress, USA) at 2 g/kg.

    Techniques: Enzyme-linked Immunosorbent Assay, Clinical Proteomics, Activity Assay