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ryanodine  (Tocris)


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Bioz Manufacturer Symbol Tocris manufactures this product  
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    Structured Review

    Tocris ryanodine
    Ryanodine, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 301 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ryanodine/Ryanodine/pmc13033160-11-0-1
    Average 95 stars, based on 301 article reviews
    ryanodine - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    Blocking Assay:

    Article Title: Synapses drive local mitochondrial ATP synthesis to fuel plasticity
    Article Snippet: .. For the NMDAR block experiment, neurons were treated with 50 μM APV (Tocris, 100 mM stock made in modified E4 buffer lacking Mg 2+ ) for at least 5 min. For the L-type calcium channel block experiment, neurons were treated with 10 μM Nimodipine (Tocris, 100 mM stock made in DMSO) for at least 10 min. For SERCA block experiments, neurons were treated with 1 μM Thapsigargin (Tocris, 1 mM stock made in DMSO) or 50 μM of CPA (Alomone, 50 mM stock made in DMSO) for at least 10 min. For RyR block experiments, neurons were treated with 100 μM Ryanodine (Tocris, 25 mM stock made in DMSO) for at least 5 min. For IP3R block experiments, neurons were treated with 3 μM XestC (Tocris, 100 μM stock made in DMSO) for at least 40 min. ..

    Modification:

    Article Title: Synapses drive local mitochondrial ATP synthesis to fuel plasticity
    Article Snippet: .. For the NMDAR block experiment, neurons were treated with 50 μM APV (Tocris, 100 mM stock made in modified E4 buffer lacking Mg 2+ ) for at least 5 min. For the L-type calcium channel block experiment, neurons were treated with 10 μM Nimodipine (Tocris, 100 mM stock made in DMSO) for at least 10 min. For SERCA block experiments, neurons were treated with 1 μM Thapsigargin (Tocris, 1 mM stock made in DMSO) or 50 μM of CPA (Alomone, 50 mM stock made in DMSO) for at least 10 min. For RyR block experiments, neurons were treated with 100 μM Ryanodine (Tocris, 25 mM stock made in DMSO) for at least 5 min. For IP3R block experiments, neurons were treated with 3 μM XestC (Tocris, 100 μM stock made in DMSO) for at least 40 min. ..

    Activity Assay:

    Article Title: The air pollutant phenanthrene disrupts calcium cycling and alters repolarization in female sheep ventricular cardiomyocytes
    Article Snippet: .. To assess the impact of phenanthrene exposure on intracellular calcium cycling through the sarcoplasmic reticulum (SR), Fluo‐4 am loaded myocytes were preincubated for 30 min prior to the start of the experiment with 2 μm thapsigargin (cat no: 1138, Tocris) to inhibit sarco(endo)plasmic reticulum calcium ATPase (SERCA) activity and 10 μM ryanodine (cat no 1329, Tocris) to inhibit SR calcium release channels (ryanodine receptors) and then calcium transients were recorded before and after phenanthrene exposure as described above. ..

    other:

    Article Title: Dobutamine, Epinephrine, and Milrinone Accelerate Particle Transport Velocity in Murine Tracheal Epithelium via Ca 2+ Release from Caffeine-Sensitive Internal Stores.
    Article Snippet: The following drugs were applied during the experiments: 2-aminoethoxydiphenylborane (2-APB, 40 μM diluted in 8 μL dimethyl sulfoxide (DMSO), TOCRIS Bioscience, Bristol, UK), adenosine triphosphate (ATP, 150 μM in 6 μL H2O, Sigma-Aldrich, St. Louis, MO, USA), caffeine (30 mM in 600 μL HEPES, Roth, Karlsruhe, Germany), CGP20712A (0.1 μM diluted in 2 μL H2O or 100 μM diluted in 20 μL H2O, TOCRIS Bioscience, Bristol, UK), dobutamine (75.7 nM in 100 μL H2O, Fresenius Kabi Deutschland GmbH, Bad Homburg v.d.H, Germany), epinephrine (87.0 nM in 100 μL H2O, Cheplapharma, Greifswald, Germany), H-89 (10 μM diluted in 20 μL DMSO, Sigma-Aldrich, St. Louis, MO, USA), ICI-118551 (100 μM in 20 μL H2O, Merck KGaA, Darmstadt, Germany) milrinone (13.7 μM in 100 μL H2O, Hikma Pharmaceuticals, London, UK), ryanodine (40 μM in 32 μL DMSO, TOCRIS Bioscience, Bristol, UK), U-73122 (2.5 μM diluted in 2 μL DMSO, Enzo Life Sciences, Farmingdale, NY, USA).

    Article Title: Dobutamine, Epinephrine, and Milrinone Accelerate Particle Transport Velocity in Murine Tracheal Epithelium via Ca 2+ Release from Caffeine-Sensitive Internal Stores
    Article Snippet: The following drugs were applied during the experiments: 2-aminoethoxydiphenylborane (2-APB, 40 μM diluted in 8 μL dimethyl sulfoxide (DMSO), TOCRIS Bioscience, Bristol, UK), adenosine triphosphate (ATP, 150 μM in 6 μL H 2 O, Sigma-Aldrich, St. Louis, MO, USA), caffeine (30 mM in 600 μL HEPES, Roth, Karlsruhe, Germany), CGP20712A (0.1 μM diluted in 2 μL H 2 O or 100 μM diluted in 20 μL H 2 O, TOCRIS Bioscience, Bristol, UK), dobutamine (75.7 nM in 100 μL H 2 O, Fresenius Kabi Deutschland GmbH, Bad Homburg v.d.H, Germany), epinephrine (87.0 nM in 100 μL H 2 O, Cheplapharma, Greifswald, Germany), H-89 (10 μM diluted in 20 μL DMSO, Sigma-Aldrich, St. Louis, MO, USA), ICI-118551 (100 μM in 20 μL H 2 O, Merck KGaA, Darmstadt, Germany) milrinone (13.7 μM in 100 μL H 2 O, Hikma Pharmaceuticals, London, UK), ryanodine (40 μM in 32 μL DMSO, TOCRIS Bioscience, Bristol, UK), U-73122 (2.5 μM diluted in 2 μL DMSO, Enzo Life Sciences, Farmingdale, NY, USA).

    Article Title: Isoflurane causes muscle contraction in Drosophila melanogaster despite inducing hyperpolarized state
    Article Snippet: Ryanodine (TOCRIS 614 McKinley Place NE Minneapolis, MN 55413 USA).



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