Journal: Biomaterials Research
Article Title: Synergistic Ion-Releasing Nanoparticles as a Therapeutic Platform for Modulating Adult Stem Cell Activity in Wound Healing
doi: 10.34133/bmr.0281
Figure Lengend Snippet: Enhanced wound healing ability of SC@ZFNs. (A and B) Scratch assay of fibroblasts co-cultured with the SC@ZFNs group for 24 h and quantification of cell migration ( n = 5, * P < 0.05 vs. SC group). Relative expression of (C) FGF2 and (D) KI67 in fibroblasts after 24-h co-culture with the SC@ZFNs group ( n = 3, * P < 0.05 vs. SC group). (E and F) Scratch assay of keratinocytes co-cultured with the SC@ZFNs group for 24 h and quantification of cell migration ( n = 5, * P < 0.05 vs. SC group). Relative expression of (G) MMP-8 and (H) TP63 in keratinocytes after 24-h co-culture with the SC@ZFNs group ( n = 3, * P < 0.05 vs. SC group).
Article Snippet: Normal human epidermal keratinocytes were purchased from PromoCell (Heidelberg, Germany) and cultured in keratinocyte growth medium 2 (PromoCell, Heidelberg, Germany) supplemented with 1% (v/v) PS.
Techniques: Wound Healing Assay, Cell Culture, Migration, Expressing, Co-Culture Assay