Journal: Drug Design, Development and Therapy
Article Title: The Mechanism of Xuanyu Tongjing Decoction Regulating NOD/NFκB Pathway to Inhibit Ectopic Tissue Inflammation to Reduce Ovarian Damage in Rats with Ovarian Endometriosis
doi: 10.2147/DDDT.S500129
Figure Lengend Snippet: Immunohistochemistry. ( A-C ) This figure’s left side represents the detected target, while its upper side is labeled as the group. In ectopic tissues, the detection targets were NFκB1 and IL-1β, while in ovarian tissues, they were CASP9, GSTM5, and SEC61B. Normal ovarian and endometrial tissue made up Group C. The slices were 10 times larger thanks to the CaseViewer program.
Article Snippet: Estradiol benzoate (Shanghai Quanyu Biotechnology Animal Pharmaceutical: 240337), sesame oil (Shanghai Yuanye Biotechnology: BYBZ23929), sodium penicillin (Shandong Bomi Biotechnology: QMS-50) (1.6×105U·kg-1 penicillin sodium), crystal violet solution (Biosharp: BL802A), cell culture medium (Beijing Soleobal: 240006015), HE staining solution (Servicebio: G1005-100ML), NOD1 Rabbit pAb (Abclonal: A1246), NOD2 Rabbit pAb (Abclonal: A25228), RIPK2 Polyclonal antibody (Proteintech: 15366-1-AP), Anti -Iκκ gamma Rabbit pAb (Servicebio: GB11628-100), Anti-IκB alpha Rabbit pAb (Servicebio: GB111509-100), NFκB1 Polyclonal antibody (Proteintech: 14220-1-AP), Anti-IL-1 beta Rabbit pAb (Servicebio: GB11113-100), Anti-TNF-alpha Rabbit pAb (Servicebio: GB11188-100), Anti-ADCY2 Rabbit pAb (Servicebio: GB114825-100), PDE3B Polyclonal antibody (Proteintech: 25290-1-AP), Anti-AKT3 Rabbit pAb (Servicebio: GB115583-100), Anti-PI3 Kinase p85 alpha Rabbit pAb (Servicebio: GB11525-50), GSTM5 Polyclonal antibody (Proteintech: 14502-1-AP), Anti-GSTM5 Rabbit pAb (Servicebio: GB113591-100), SEC61B Polyclonal antibody (Proteintech: 25290-1-AP), Caspase 9 Polyclonal antibody (Proteintech: 25290-1-AP).
Techniques: Immunohistochemistry, Labeling