Journal: Clinical and Translational Allergy
Article Title: Pets, furry animal allergen components, and asthma in childhood
doi: 10.1002/clt2.12337
Figure Lengend Snippet: (A–C) The odds ratio with 95% confidence interval between (A) blood eosinophilia (%), (B) FeNO, and (C) lung function measurements and >0.3 ISAC‐standardized units sensitization to individual IgE components of furry animals. Blood eosinophil count ≥4% was considered eosinophilia. ≥40% increase in R5 in IOS, ≥12% decrease in FEV1 in spirometria, or both were interpreted as positive BDT. FeNO z ‐score ≥2 SD was considered positive. BDT, bronchodilation test; CI, confidence interval; FeNO, fractional concentration of exhaled nitric oxide; IOS, impulse oscillometry.
Article Snippet: An ISAC multiplex microarray (ISAC Chip, Thermo Fisher Scientific) was used to analyze IgE‐sensitization to 112 different allergen components.
Techniques: Concentration Assay