massarray system (Sequenom)

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Sequenom massarray system
Massarray System, supplied by Sequenom, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/massarray-system/massarray+platform/pm42302540-52-6-8
Average 86 stars, based on 1 article reviews

massarray system - by Bioz Stars, 2026-09

86/100 stars

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DNA Methylation Assay:

Article Title: Diet intervention altered DNA methylation of potassium voltage-gated channel subfamily Q member 1 in metabolic dysfunction-associated steatohepatitis
Article Snippet: .. The contributions of this study include a low-fat diet intervention in MASLD on DNA methylation in intron regions with animal experiment replication and validation with quantitative methylation analysis via Sequenom’s MassARRAY system for the candidate gene across tissues. ..

Biomarker Discovery:

Article Title: Development of a MALDI-TOF nucleic acid mass spectrometry-based assay for the detection of 10 major avian diseases.
Article Snippet: Outbreaks of avian diseases such as avian influenza, Newcastle disease, infectious bronchitis, and others pose a significant threat to the global poultry industry and public health.. This study aims to develop a rapid, highthroughput multi-target assay for the simultaneous detection of key diseases such as avian influenza (AIV), Newcastle disease (NDV), infectious bronchitis (IBV), infectious laryngotracheitis (ILTV), fowl pox (FPV), avian adenovirus (FAdV), and avian metapneumovirus (AMPV), all of which are commonly found in avian farming.. This method is based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDITOF MS) technology and involves the design of specific multiplex primers for the three subtypes of the target disease AIV (H5/H7/H9) and generic types, NDV, IBV, ILTV, FPV, FAdV, and AMPV.

Methylation:

other:

Article Title: Genetic associations of LXN polymorphisms with toxicities of platinum-based concurrent chemoradiotherapy of nasopharyngeal carcinoma.
Article Snippet: LXN genotypes were analyzed by the Sequenom MassARRAY system.

Article Title: Genetic associations of LXN polymorphisms with toxicities of platinum-based concurrent chemoradiotherapy of nasopharyngeal carcinoma
Article Snippet: LXN genotypes were analyzed by the Sequenom MassARRAY system.

DNA Purification:

Article Title: Integrating genetic and lifestyle determinants in a risk prediction model for esophageal squamous cell carcinoma in Taiwan.
Article Snippet: .. Genomic DNA was extracted from peripheral blood using the Puregene DNA Purification Kit (Gentra Systems, Minneapolis, MN, USA) and the resulting DNA was dispensed into 96-well plates (ABgene Limited, Epsom, UK). and samples Samples with concentrations ≥2.5 ng/μl were genotyped using the Sequenom MassARRAY system (with call rate > 95%). ..

Polymerase Chain Reaction:

Article Title: Comprehensive Analysis of PAPPA2 Expression and Genetic Variants in Sheep and Their Association With Litter Size
Article Snippet: .. Genotyping was performed on the MassARRAY system (Sequenom Inc., San Diego, CA, USA) using polymerase chain reaction (PCR), primer extension and mass spectrometry analysis (iPlex assay), following the manufacturer's instructions (available at: http://www.sequenom.com ). ..

Article Title: Phase I study of bevacizumab and temsirolimus combination therapy in advanced malignancies: safety, efficacy, and ovarian cancer expansion
Article Snippet: .. 2 , 0 , Tissue based , Knight Cancer Institute/Knight Diagnostic Laboratories , Sequenom MassARRAY system-multiplex PCR amplification of gene exons of interest; primer extension reaction using TYPLEX chemistry; readout of primer extension products by mass spectrometry. Multiplex panel of 496 assays that can detect up to 643 different mutations. , 10% , Not provided Only approximately 20% of potential mutations are covered in the TP53 gene.. .. 7 , 7 , Tissue based , MDACC 50-Gene Somatic Mutation Analysis Panel , PCR-based sequencing using a NGS-platform on genomic DNA to screen for mutations in the coding sequence of 50 genes , SNV 5%-10% , Hotspot technology PTEN 1 (1-25), 3 (55-70), 5 (99-135), 6 (165-184), 7 (212-215), 7 (231-267), 8 (282-300), 8 (312-342) TP53 2(1-20), 4 (68-113), 5 (126-138), 5-6(149-223), 7 (225-258), 8 (263-307), 10 (332-367).

Mass Spectrometry:

Mutagenesis:

Diagnostic Assay:

Amplification:

Multiplex Assay:

Modification:

Article Title: Midlife insulin resistance and brain beta-amyloid accumulation as predictors of change in late-life cognitive function - A 20-year follow-up study.
Article Snippet: .. APOE genotype was defined with the MassARRAY System (Sequenom, San Diego, CA, USA) with a modified protocol (Jänis et al., 2004). ..

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