ovarian cancer igrov1 6 21 non small cell lung cancer nci h23 (ATCC)
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Ovarian Cancer Igrov1 6 21 Non Small Cell Lung Cancer Nci H23, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 936 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Activity Assay:Article Title: Design and synthesis of new 2,5-disubstituted-1,3,4-oxadiazole analogues as anticancer agents Article Snippet: In continuance of our search for new anticancer agents, we report herein the design, synthesis, and anticancer evaluation of oxadiazole analogues.. Two series (4a-h and 4i-q) of new oxadiazole analogues were designed based on heterocyclic (1,3,4-oxadiazole)-linked aryl core of IMC038525 (tubulin polymerization inhibitor), NSC 776715, and NSC 776715 and synthesized.. All the compounds were fully characterized by infrared, nuclear magnetic resonance spectroscopy, and mass spectral data and the purity of compounds was checked by elemental analysis (C, H, and N analysis). Concentration Assay:Article Title: Design and synthesis of new 2,5-disubstituted-1,3,4-oxadiazole analogues as anticancer agents Article Snippet: In continuance of our search for new anticancer agents, we report herein the design, synthesis, and anticancer evaluation of oxadiazole analogues.. Two series (4a-h and 4i-q) of new oxadiazole analogues were designed based on heterocyclic (1,3,4-oxadiazole)-linked aryl core of IMC038525 (tubulin polymerization inhibitor), NSC 776715, and NSC 776715 and synthesized.. All the compounds were fully characterized by infrared, nuclear magnetic resonance spectroscopy, and mass spectral data and the purity of compounds was checked by elemental analysis (C, H, and N analysis). Inhibition:Article Title: Design and synthesis of new 2,5-disubstituted-1,3,4-oxadiazole analogues as anticancer agents Article Snippet: In continuance of our search for new anticancer agents, we report herein the design, synthesis, and anticancer evaluation of oxadiazole analogues.. Two series (4a-h and 4i-q) of new oxadiazole analogues were designed based on heterocyclic (1,3,4-oxadiazole)-linked aryl core of IMC038525 (tubulin polymerization inhibitor), NSC 776715, and NSC 776715 and synthesized.. All the compounds were fully characterized by infrared, nuclear magnetic resonance spectroscopy, and mass spectral data and the purity of compounds was checked by elemental analysis (C, H, and N analysis). Article Title: Synthesis and Anticancer Evaluation of Some Novel Thiophene, Thieno[3,2‐ d ]pyrimidine, Thieno[3,2‐ b ]pyridine, and Thieno[3,2‐ e ][1,4]oxazepine Derivatives Containing Benzothiazole Moiety Article Snippet: In an attempt to establish novel candidate with promising anticancer activity, two derivatives of (benzo[d] thiazol-2-yl)thiophene backbone 1 and 14 were synthesized, and they further reacted with various chemical reagents to afford the corresponding substituted thiophene derivatives 6, 8, 10, 15, 17, and 20, thieno[3,2-d] pyrimidine derivatives 2–5, 7, 9, 16, 21, 23, and 24, thieno[3,2-b]pyridine derivatives 11–13, and thieno[3,2e][1,4]oxazepine derivative 18.. Structures of prepared compounds were affirmed via spectral and elemental data.. Among the obtained compounds, seven derivatives 2, 3, 4, 5, 11, 12, and 13 were chosen by National Cancer Institute, USA. Multiple Displacement Amplification:Article Title: Design and synthesis of new 2,5-disubstituted-1,3,4-oxadiazole analogues as anticancer agents Article Snippet: In continuance of our search for new anticancer agents, we report herein the design, synthesis, and anticancer evaluation of oxadiazole analogues.. Two series (4a-h and 4i-q) of new oxadiazole analogues were designed based on heterocyclic (1,3,4-oxadiazole)-linked aryl core of IMC038525 (tubulin polymerization inhibitor), NSC 776715, and NSC 776715 and synthesized.. All the compounds were fully characterized by infrared, nuclear magnetic resonance spectroscopy, and mass spectral data and the purity of compounds was checked by elemental analysis (C, H, and N analysis). Article Title: A profile of 8-oxo-dGTPase activities in the NCI-60 human cancer panel: Meta-analytic insight into the regulation and role of MTH1 (NUDT1) gene expression in carcinogenesis. Article Snippet: .. For this purpose all available MTH1 z-scores (12 in most cases) for the 59 cell lines have been averaged, giving the following integrated MTH1 expression z-scores: CCRF-CEM: 2.9893, HL-60(TB): 0.8178, K-562: -0.7434, MOLT-4: -0.2775, RPMI-8226: -0.1419, SR: 0.2248, A549/ATCC: 0.2715, EKVX: 0.2858, HOP-62: -0.6308, HOP-92: -0.1013, NCI-H226: -0.6528, NCI-H23: 1.9629, NCI-H322M: 1.4084, NCI-H460: 0.0792, NCI-H522: -0.2483, COLO205: 0.6650, HCC-2998: -0.0060, HCT-116: -0.7296, HCT-15: -0.9233, HT29: -0.3817, KM12: -0.3473, SW-620: -0.2189, SF-268: 0.5170, SF-295: 0.8383, SF-539: 0.5031, SNB-19: 0.8208, SNB-75: -0.4071, U251: 2.2282, LOXIMVI: -0.1532, MALME-3M: 0.4383, M14: -0.2538, MDA-MB-435: -0.5973, SK-MEL-2: 0.1932, SK-MEL-28: 0.2586, SK-MEL-5: 0.9284, UACC-257: -0.1012, UACC-62: -0.1453, other:Article Title: Oxindole–benzothiazole hybrids as CDK2 inhibitors and anticancer agents: design, synthesis and biological evaluation Article Snippet: Article Title: Protein Paucimannosylation Is an Enriched N-Glycosylation Signature of Human Cancers. Article Snippet: Article Title: Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Article Snippet: Expressing:Article Title: A profile of 8-oxo-dGTPase activities in the NCI-60 human cancer panel: Meta-analytic insight into the regulation and role of MTH1 (NUDT1) gene expression in carcinogenesis. Article Snippet: .. For this purpose all available MTH1 z-scores (12 in most cases) for the 59 cell lines have been averaged, giving the following integrated MTH1 expression z-scores: CCRF-CEM: 2.9893, HL-60(TB): 0.8178, K-562: -0.7434, MOLT-4: -0.2775, RPMI-8226: -0.1419, SR: 0.2248, A549/ATCC: 0.2715, EKVX: 0.2858, HOP-62: -0.6308, HOP-92: -0.1013, NCI-H226: -0.6528, NCI-H23: 1.9629, NCI-H322M: 1.4084, NCI-H460: 0.0792, NCI-H522: -0.2483, COLO205: 0.6650, HCC-2998: -0.0060, HCT-116: -0.7296, HCT-15: -0.9233, HT29: -0.3817, KM12: -0.3473, SW-620: -0.2189, SF-268: 0.5170, SF-295: 0.8383, SF-539: 0.5031, SNB-19: 0.8208, SNB-75: -0.4071, U251: 2.2282, LOXIMVI: -0.1532, MALME-3M: 0.4383, M14: -0.2538, MDA-MB-435: -0.5973, SK-MEL-2: 0.1932, SK-MEL-28: 0.2586, SK-MEL-5: 0.9284, UACC-257: -0.1012, UACC-62: -0.1453, |
