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hbd-1  (PeproTech)


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    PeproTech hbd-1
    Hbd 1, supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hbd-1/recombinant+hbd+2/pmc11684945-98-2-3
    Average 90 stars, based on 1 article reviews
    hbd-1 - by Bioz Stars, 2026-10
    90/100 stars

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    other:

    Article Title: Gene expression responses of CF airway epithelial cells exposed to elexacaftor/tezacaftor/ivacaftor suggest benefits beyond improved CFTR channel function.
    Article Snippet: Measurement of Cytokines and Beta-Defensin 1 by ELISA Secretion of hBD-1 (PeproTech: #900-K202), IL-6, IL-8, GCSF, and MCP1 (R & D Systems: #DY206, #DY208, #DY214, #DY279) by CF AECs exposed to ETI or vehicle was measured by ELISA in triplicate wells per sample as recommended by R&D Systems.

    Article Title: The Vaginal Microbiota and Innate Immunity After Local Excisional Treatment for Cervical Intraepithelial Neoplasia
    Article Snippet: Slides were cut from para n-embedded blocks, depara nised and a horseradish peroxidase-3,3’ Diaminobenzidine Cell & Tissue staining kit (R&D systems) was used according to manufacturers’ instructions along with hBD-1 (Peprotech) at 1:10 dilution and SLPI antibodies (Hycult Biotech) used at 1:5 dilution.

    Article Title: Gene expression responses of CF airway epithelial cells exposed to elexacaftor/tezacaftor/ivacaftor suggest benefits beyond improved CFTR channel function
    Article Snippet: Secretion of hBD-1 (PeproTech: #900-K202), IL-6, IL-8, G-CSF, and MCP1 (R & D Systems: #DY206, #DY208, #DY214, #DY279) by CF AECs exposed to ETI or vehicle was measured by ELISA in triplicate wells per sample as recommended by R&D Systems.

    Article Title: The lower airways microbiota and antimicrobial peptides indicate dysbiosis in sarcoidosis
    Article Snippet: The AMPs, SLPI [ ], and hBD-1 (PeproTech, London; UK) and hBD-2 (Antigenix America, Melville, NY, USA), were measured in PBAL by enzyme-linked immunosorbent assay (ELISA), performed at the Leiden University Medical Center, the Netherlands.

    Article Title: The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease
    Article Snippet: SLPI [ ] and hBD-1 (PeproTech, London; UK) & hBD-2 (Antigenix America, Melville, NY, US) were measured in PBAL by enzyme linked immunosorbent assay (ELISA), performed at the Leiden University Medical Center, the Netherlands.



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    Image Search Results


    Human β-defensin-1 affects the viability, clonogenesis, and autophagy of SW620 cells. A: Human β-defensin-1 (hBD-1) suppresses cell viability; B: hBD-1 inhibits clonal formation; C: Clonal formation count; D: hBD-1 inhibits phosphorylation of mTOR and promotes expression of Beclin-1 and LC3II/I; E-G: Relative expression of p-mTOR, Beclin-1, and LC3II/I. a P < 0.05 vs control group. hBD-1: Human β-defensin-1.

    Journal: World Journal of Gastrointestinal Oncology

    Article Title: Human β-defensin-1 affects the mammalian target of rapamycin pathway and autophagy in colon cancer cells through long non-coding RNA TCONS_00014506

    doi: 10.4251/wjgo.v16.i4.1465

    Figure Lengend Snippet: Human β-defensin-1 affects the viability, clonogenesis, and autophagy of SW620 cells. A: Human β-defensin-1 (hBD-1) suppresses cell viability; B: hBD-1 inhibits clonal formation; C: Clonal formation count; D: hBD-1 inhibits phosphorylation of mTOR and promotes expression of Beclin-1 and LC3II/I; E-G: Relative expression of p-mTOR, Beclin-1, and LC3II/I. a P < 0.05 vs control group. hBD-1: Human β-defensin-1.

    Article Snippet: The human colon cancer cell line SW620 was obtained from Wuhan Procell Life Science & Technology Co., Ltd, and hBD-1 was purchased from Sino Biological, Inc. (China).

    Techniques: Expressing

    Bioinformatics analysis of differentially expressed long non-coding RNAs and selection of the target long non-coding RNA. A: KEGG pathway enrichment analysis. The bubble size denotes the number of long non-coding RNAs ( lncRNAs) target genes enriched in this pathway. Larger bubbles denote a higher number of target genes associated with the pathway. Darker color indicates more significant enrichment. The abscissa count indicates the number of genes in this pathway, and the ordinate signifies the KEGG pathway; B: GO pathway enrichment analysis. Bubble size signifies the number of lncRNA target genes enriched in this pathway, with a larger bubble indicating a larger number of target genes. Darker color indicates more significant enrichment. The abscissa count denotes the number of target genes, and the ordinate denotes a GO term; C: Co-expression analysis of differentially expressed lncRNAs and differentially expressed mRNAs. Inverted triangles indicate lncRNAs, circles indicate mRNAs, red color indicates upregulated expression, and green color indicates downregulated expression; D: KEGG pathways classification analysis. From left to right are cellular processes, environmental information processing, genetic information processing, and human diseases, metabolism, organismal systems; E: GO pathways classification analysis. Red parts indicate biological processes, blue parts indicate cellular components, and green parts indicate molecular function; F: LncRNA expression was detected via qRT-PCR. a P < 0.05 vs control group. hBD-1: Human β-defensin-1.

    Journal: World Journal of Gastrointestinal Oncology

    Article Title: Human β-defensin-1 affects the mammalian target of rapamycin pathway and autophagy in colon cancer cells through long non-coding RNA TCONS_00014506

    doi: 10.4251/wjgo.v16.i4.1465

    Figure Lengend Snippet: Bioinformatics analysis of differentially expressed long non-coding RNAs and selection of the target long non-coding RNA. A: KEGG pathway enrichment analysis. The bubble size denotes the number of long non-coding RNAs ( lncRNAs) target genes enriched in this pathway. Larger bubbles denote a higher number of target genes associated with the pathway. Darker color indicates more significant enrichment. The abscissa count indicates the number of genes in this pathway, and the ordinate signifies the KEGG pathway; B: GO pathway enrichment analysis. Bubble size signifies the number of lncRNA target genes enriched in this pathway, with a larger bubble indicating a larger number of target genes. Darker color indicates more significant enrichment. The abscissa count denotes the number of target genes, and the ordinate denotes a GO term; C: Co-expression analysis of differentially expressed lncRNAs and differentially expressed mRNAs. Inverted triangles indicate lncRNAs, circles indicate mRNAs, red color indicates upregulated expression, and green color indicates downregulated expression; D: KEGG pathways classification analysis. From left to right are cellular processes, environmental information processing, genetic information processing, and human diseases, metabolism, organismal systems; E: GO pathways classification analysis. Red parts indicate biological processes, blue parts indicate cellular components, and green parts indicate molecular function; F: LncRNA expression was detected via qRT-PCR. a P < 0.05 vs control group. hBD-1: Human β-defensin-1.

    Article Snippet: The human colon cancer cell line SW620 was obtained from Wuhan Procell Life Science & Technology Co., Ltd, and hBD-1 was purchased from Sino Biological, Inc. (China).

    Techniques: Selection, Expressing, Quantitative RT-PCR

    Human β-defensin-1 inhibits phosphorylation of mTOR and promotes autophagy in SW620 cells through long non-coding RNA TCONS_14506. A: Long non-coding RNA (lncRNA) TCONS_00014506 expression at RNA level; B: Western blot analysis demonstrated the protein expression levels of p-mTOR (Ser2448), Beclin-1, and LC3II/I; C-E: Relative expression of p-mTOR, Beclin-1, and LC3II/I. a P < 0.05 vs control group; b P < 0.05 vs human β-defensin-1 group; c P < 0.05 vs si-lncRNA group. P < 0.05 was considered statistically significant. hBD-1: Human β-defensin-1; lncRNA: Long non-coding RNA.

    Journal: World Journal of Gastrointestinal Oncology

    Article Title: Human β-defensin-1 affects the mammalian target of rapamycin pathway and autophagy in colon cancer cells through long non-coding RNA TCONS_00014506

    doi: 10.4251/wjgo.v16.i4.1465

    Figure Lengend Snippet: Human β-defensin-1 inhibits phosphorylation of mTOR and promotes autophagy in SW620 cells through long non-coding RNA TCONS_14506. A: Long non-coding RNA (lncRNA) TCONS_00014506 expression at RNA level; B: Western blot analysis demonstrated the protein expression levels of p-mTOR (Ser2448), Beclin-1, and LC3II/I; C-E: Relative expression of p-mTOR, Beclin-1, and LC3II/I. a P < 0.05 vs control group; b P < 0.05 vs human β-defensin-1 group; c P < 0.05 vs si-lncRNA group. P < 0.05 was considered statistically significant. hBD-1: Human β-defensin-1; lncRNA: Long non-coding RNA.

    Article Snippet: The human colon cancer cell line SW620 was obtained from Wuhan Procell Life Science & Technology Co., Ltd, and hBD-1 was purchased from Sino Biological, Inc. (China).

    Techniques: Expressing, Western Blot