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h-151  (InvivoGen)


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Bioz Manufacturer Symbol InvivoGen manufactures this product  
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    Structured Review

    InvivoGen h-151
    H 151, supplied by InvivoGen, used in various techniques. Bioz Stars score: 95/100, based on 4836 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/h151/H-151/custom%40inh-h151-5%4010%2E64898%2F2026%2E07%2E17%2E738478
    Average 95 stars, based on 4836 article reviews
    h-151 - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    Transfection:

    Article Title: Discovery of 3,4-dihydroisoquinoline-2(1H)-carboxamide STING inhibitors as anti-inflammatory agents.
    Article Snippet: Stimulator of interferon genes (STING) is an endoplasmic reticulum-localized adaptor protein that plays a vital role in mediating the cytosolic DNA-sensing pathway to prime the innate immune responses.. Overactivated STING axis causes excessive accumulation of interferons and proinflammatory cytokines, leading to autoimmune and autoinflammatory diseases such as STING-associated vasculopathy of infancy (SAVI) and Aicardi− Goutières syndrome (AGS).. Inhibiting the aberrant STING signaling with its inhibitors has proven to alleviate the inflammatory symptoms of the autoimmune and autoinflammatory diseases.

    Purification:

    Article Title: Discovery of 3,4-dihydroisoquinoline-2(1H)-carboxamide STING inhibitors as anti-inflammatory agents.
    Article Snippet: Stimulator of interferon genes (STING) is an endoplasmic reticulum-localized adaptor protein that plays a vital role in mediating the cytosolic DNA-sensing pathway to prime the innate immune responses.. Overactivated STING axis causes excessive accumulation of interferons and proinflammatory cytokines, leading to autoimmune and autoinflammatory diseases such as STING-associated vasculopathy of infancy (SAVI) and Aicardi− Goutières syndrome (AGS).. Inhibiting the aberrant STING signaling with its inhibitors has proven to alleviate the inflammatory symptoms of the autoimmune and autoinflammatory diseases.

    Concentration Assay:

    Article Title: The ability of SAMHD1-deficient monocytes to trigger the Type I IFN response depends on cGAS and mitochondrial DNA
    Article Snippet: .. Cells were treated at the indicated concentration with G140 (Invivogen) or H151 (Invivogen). ..

    Article Title: The ability of SAMHD1-deficient monocytes to trigger the type I IFN response depends on cGAS and mitochondrial DNA.
    Article Snippet: .. Cells were treated at the indicated concentration with G140 (Invivogen) or H151 (Invivogen). ..

    Article Title: Enhancement of NK cell activity via DNA-sensing inhibition by Poxin transgene
    Article Snippet: .. H151 (inh-h151, InvivoGen, San Diego, CA, USA) was used at a concentration of 1 μM. ..

    other:

    Article Title: Chronic Cellular NAD Depletion Activates a Viral Infection‐Like Interferon Response Through Mitochondrial DNA Leakage
    Article Snippet: Cells in NAM or NAM Free media were treated with the following drugs: 5 μM VBIT‐4 (Selleckchem, S3544), 1.5 μM H151 (InvivoGen, inh‐h151), 3 μM C‐176 (Selleckchem S6575), 15 μM 2′3′‐cGAMP (APExBIO, 1441190‐66‐4), 5 nM FK866 (Sigma‐Aldrich Inc., F8557), and 250 μM phthalic acid (Sigma‐Aldrich Inc., P2944).

    Article Title: Chronic Cellular NAD Depletion Activates a Viral Infection-Like Interferon Response Through Mitochondrial DNA Leakage.
    Article Snippet: Cells in NAM or NAM Free media were treated with the following drugs: 5 μM VBIT- 4 (Selleckchem, S3544), 1.5 μM H151 (InvivoGen, inh- h151), 3 μM C- 176 (Selleckchem S6575), 15 μM 2′3′- cGAMP (APExBIO, 1441190- 66- 4), 5 nM FK866 (SigmaAldrich Inc., F8557), and 250 μM phthalic acid (Sigma- Aldrich Inc., P2944).

    Binding Assay:

    Article Title: Extracellular Cold-Inducible RNA-Binding Protein and Hemorrhagic Shock: Mechanisms and Therapeutics.
    Article Snippet: .. H151 is a potent, selectively binding, and irreversible inhibitor of STING developed by Invivogen [80]. ..



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