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Withdrawal periods of <t>fluralaner</t> solution in edible chicken tissues.
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Withdrawal periods of <t>fluralaner</t> solution in edible chicken tissues.
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Facility design for the dose confirmation study. Cages separated by treatment group (Control or Medicated) to reduce possible cross-contamination, and each treatment group organized into four cage blocks with four cages in each block (Control: 1A–4D; Medicated: 5A–8D). Cages A and B were positioned above cages C and D in each cage block, with top and bottom cages separated by a metal shelf. Each cage held four birds with NFM counts on birds balanced across treatment groups, cage blocks, and cages within a block. Care was taken throughout the study to prevent transfer of <t>fluralaner</t> medication or mites among birds in different cage blocks and treatment groups
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Facility design for the dose confirmation study. Cages separated by treatment group (Control or Medicated) to reduce possible cross-contamination, and each treatment group organized into four cage blocks with four cages in each block (Control: 1A–4D; Medicated: 5A–8D). Cages A and B were positioned above cages C and D in each cage block, with top and bottom cages separated by a metal shelf. Each cage held four birds with NFM counts on birds balanced across treatment groups, cage blocks, and cages within a block. Care was taken throughout the study to prevent transfer of <t>fluralaner</t> medication or mites among birds in different cage blocks and treatment groups
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Withdrawal periods of fluralaner solution in edible chicken tissues.

Journal: Poultry Science

Article Title: Residue depletion and withdrawal period determination of fluralaner in edible tissues and eggs following oral administration in laying Hens

doi: 10.1016/j.psj.2026.106899

Figure Lengend Snippet: Withdrawal periods of fluralaner solution in edible chicken tissues.

Article Snippet: In Europe and Australia, fluralaner (Exzolt®, Merck Animal Health) is the only isoxazoline-class medicinal product approved for use in poultry ( ).

Techniques:

Facility design for the dose confirmation study. Cages separated by treatment group (Control or Medicated) to reduce possible cross-contamination, and each treatment group organized into four cage blocks with four cages in each block (Control: 1A–4D; Medicated: 5A–8D). Cages A and B were positioned above cages C and D in each cage block, with top and bottom cages separated by a metal shelf. Each cage held four birds with NFM counts on birds balanced across treatment groups, cage blocks, and cages within a block. Care was taken throughout the study to prevent transfer of fluralaner medication or mites among birds in different cage blocks and treatment groups

Journal: Parasites & Vectors

Article Title: Efficacy of fluralaner solution administered to egg layer chickens through drinking water for control of northern fowl mite ( Ornithonyssus sylviarum )

doi: 10.1186/s13071-025-07240-w

Figure Lengend Snippet: Facility design for the dose confirmation study. Cages separated by treatment group (Control or Medicated) to reduce possible cross-contamination, and each treatment group organized into four cage blocks with four cages in each block (Control: 1A–4D; Medicated: 5A–8D). Cages A and B were positioned above cages C and D in each cage block, with top and bottom cages separated by a metal shelf. Each cage held four birds with NFM counts on birds balanced across treatment groups, cage blocks, and cages within a block. Care was taken throughout the study to prevent transfer of fluralaner medication or mites among birds in different cage blocks and treatment groups

Article Snippet: Fluralaner oral solution (10 mg/mL) was acquired from Merck Animal Health (Rahway, NJ, USA) and mixed into drinking water for oral consumption by chickens.

Techniques: Control, Blocking Assay

Facility design for the field efficacy trial. Cages separated according to treatment group (Control: 1–200; Medicated: 201–400) with two birds in each cage. Care was taken throughout the study to prevent transfer of fluralaner medication or mites between treatment groups, though poultry houses on this farm were open-sided (no walls) allowing access by wild birds, which were noted to occasionally rest on cages or feed troughs

Journal: Parasites & Vectors

Article Title: Efficacy of fluralaner solution administered to egg layer chickens through drinking water for control of northern fowl mite ( Ornithonyssus sylviarum )

doi: 10.1186/s13071-025-07240-w

Figure Lengend Snippet: Facility design for the field efficacy trial. Cages separated according to treatment group (Control: 1–200; Medicated: 201–400) with two birds in each cage. Care was taken throughout the study to prevent transfer of fluralaner medication or mites between treatment groups, though poultry houses on this farm were open-sided (no walls) allowing access by wild birds, which were noted to occasionally rest on cages or feed troughs

Article Snippet: Fluralaner oral solution (10 mg/mL) was acquired from Merck Animal Health (Rahway, NJ, USA) and mixed into drinking water for oral consumption by chickens.

Techniques: Control

Mean number (± standard error, SE) of mites on layer chickens (~ 20 weeks old) in the field efficacy trial. Chickens received either untreated drinking water or fluralaner administered in drinking water at 0.5 mg/kg body weight on day 0 and day 7 (treatment dates indicated with grey arrows). Significance indicated at P < 0.0001 (***) or not significant (NS)

Journal: Parasites & Vectors

Article Title: Efficacy of fluralaner solution administered to egg layer chickens through drinking water for control of northern fowl mite ( Ornithonyssus sylviarum )

doi: 10.1186/s13071-025-07240-w

Figure Lengend Snippet: Mean number (± standard error, SE) of mites on layer chickens (~ 20 weeks old) in the field efficacy trial. Chickens received either untreated drinking water or fluralaner administered in drinking water at 0.5 mg/kg body weight on day 0 and day 7 (treatment dates indicated with grey arrows). Significance indicated at P < 0.0001 (***) or not significant (NS)

Article Snippet: Fluralaner oral solution (10 mg/mL) was acquired from Merck Animal Health (Rahway, NJ, USA) and mixed into drinking water for oral consumption by chickens.

Techniques:

Egg production (eggs/bird/day) for Medicated and Control treatment groups. Egg production per treatment group (400 layers in each group) was recorded daily from day −4 through day 28 post-treatment. Fluralaner was administered to Medicated group birds on days 0 and 7 as indicated by arrows

Journal: Parasites & Vectors

Article Title: Efficacy of fluralaner solution administered to egg layer chickens through drinking water for control of northern fowl mite ( Ornithonyssus sylviarum )

doi: 10.1186/s13071-025-07240-w

Figure Lengend Snippet: Egg production (eggs/bird/day) for Medicated and Control treatment groups. Egg production per treatment group (400 layers in each group) was recorded daily from day −4 through day 28 post-treatment. Fluralaner was administered to Medicated group birds on days 0 and 7 as indicated by arrows

Article Snippet: Fluralaner oral solution (10 mg/mL) was acquired from Merck Animal Health (Rahway, NJ, USA) and mixed into drinking water for oral consumption by chickens.

Techniques: Control