Review





Similar Products

notch inhibitors  (MedChemExpress)
95
MedChemExpress notch inhibitors
Notch Inhibitors, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/notch inhibitors/product/MedChemExpress
Average 95 stars, based on 1 article reviews
notch inhibitors - by Bioz Stars, 2026-05
95/100 stars
  Buy from Supplier
dapt thermo fisher scientific  (Thermo Fisher)
95
Thermo Fisher dapt thermo fisher scientific
Dapt Thermo Fisher Scientific, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/dapt thermo fisher scientific/product/Thermo Fisher
Average 95 stars, based on 1 article reviews
dapt thermo fisher scientific - by Bioz Stars, 2026-05
95/100 stars
  Buy from Supplier
dapt  (Tocris)
96
Tocris dapt
Dapt, supplied by Tocris, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/dapt/product/Tocris
Average 96 stars, based on 1 article reviews
dapt - by Bioz Stars, 2026-05
96/100 stars
  Buy from Supplier
dapt  (Thermo Fisher)
95
Thermo Fisher dapt
Dapt, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/dapt/product/Thermo Fisher
Average 95 stars, based on 1 article reviews
dapt - by Bioz Stars, 2026-05
95/100 stars
  Buy from Supplier
gamma secretase inhibitor dapt emd millipore  (Thermo Fisher)
95
Thermo Fisher gamma secretase inhibitor dapt emd millipore
Gamma Secretase Inhibitor Dapt Emd Millipore, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/gamma secretase inhibitor dapt emd millipore/product/Thermo Fisher
Average 95 stars, based on 1 article reviews
gamma secretase inhibitor dapt emd millipore - by Bioz Stars, 2026-05
95/100 stars
  Buy from Supplier
notch inhibitor dapt  (Tocris)
96
Tocris notch inhibitor dapt
(a) αSMA mRNA levels in HCAEC treated with TGFβ1 (10 ng/ml) or exposed to hypoxic conditions (5% O 2 ), in the absence or presence of moderate dose EtOH (25 mM, green bars) or high dose EtOH (100 mM, red bars) +/- the <t>γ-secretase</t> <t>inhibitor</t> <t>DAPT</t> (20 μM). (b) αSMA and fibronectin (FN) mRNA levels in HCAEC treated with TGFβ1 +/- the Notch ligand DLL4 (3 μg/ml) in the absence or presence of DAPT (20 μM). Data are mean±SEM, n=3. *p<0.05 vs control (no treatment), #p<0.05 vs TGFβ1 or hypoxia.
Notch Inhibitor Dapt, supplied by Tocris, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/notch inhibitor dapt/product/Tocris
Average 96 stars, based on 1 article reviews
notch inhibitor dapt - by Bioz Stars, 2026-05
96/100 stars
  Buy from Supplier
notch1 signaling  (MedChemExpress)
95
MedChemExpress notch1 signaling
(a) αSMA mRNA levels in HCAEC treated with TGFβ1 (10 ng/ml) or exposed to hypoxic conditions (5% O 2 ), in the absence or presence of moderate dose EtOH (25 mM, green bars) or high dose EtOH (100 mM, red bars) +/- the <t>γ-secretase</t> <t>inhibitor</t> <t>DAPT</t> (20 μM). (b) αSMA and fibronectin (FN) mRNA levels in HCAEC treated with TGFβ1 +/- the Notch ligand DLL4 (3 μg/ml) in the absence or presence of DAPT (20 μM). Data are mean±SEM, n=3. *p<0.05 vs control (no treatment), #p<0.05 vs TGFβ1 or hypoxia.
Notch1 Signaling, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/notch1 signaling/product/MedChemExpress
Average 95 stars, based on 1 article reviews
notch1 signaling - by Bioz Stars, 2026-05
95/100 stars
  Buy from Supplier
dapt treatment  (Tocris)
92
Tocris dapt treatment
(a) αSMA mRNA levels in HCAEC treated with TGFβ1 (10 ng/ml) or exposed to hypoxic conditions (5% O 2 ), in the absence or presence of moderate dose EtOH (25 mM, green bars) or high dose EtOH (100 mM, red bars) +/- the <t>γ-secretase</t> <t>inhibitor</t> <t>DAPT</t> (20 μM). (b) αSMA and fibronectin (FN) mRNA levels in HCAEC treated with TGFβ1 +/- the Notch ligand DLL4 (3 μg/ml) in the absence or presence of DAPT (20 μM). Data are mean±SEM, n=3. *p<0.05 vs control (no treatment), #p<0.05 vs TGFβ1 or hypoxia.
Dapt Treatment, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/dapt treatment/product/Tocris
Average 92 stars, based on 1 article reviews
dapt treatment - by Bioz Stars, 2026-05
92/100 stars
  Buy from Supplier

Image Search Results


(a) αSMA mRNA levels in HCAEC treated with TGFβ1 (10 ng/ml) or exposed to hypoxic conditions (5% O 2 ), in the absence or presence of moderate dose EtOH (25 mM, green bars) or high dose EtOH (100 mM, red bars) +/- the γ-secretase inhibitor DAPT (20 μM). (b) αSMA and fibronectin (FN) mRNA levels in HCAEC treated with TGFβ1 +/- the Notch ligand DLL4 (3 μg/ml) in the absence or presence of DAPT (20 μM). Data are mean±SEM, n=3. *p<0.05 vs control (no treatment), #p<0.05 vs TGFβ1 or hypoxia.

Journal: bioRxiv

Article Title: A Biphasic Effect of Alcohol on Endothelial Plasticity Through Regulation of Endothelial-to-Mesenchymal Transition

doi: 10.64898/2026.04.14.718463

Figure Lengend Snippet: (a) αSMA mRNA levels in HCAEC treated with TGFβ1 (10 ng/ml) or exposed to hypoxic conditions (5% O 2 ), in the absence or presence of moderate dose EtOH (25 mM, green bars) or high dose EtOH (100 mM, red bars) +/- the γ-secretase inhibitor DAPT (20 μM). (b) αSMA and fibronectin (FN) mRNA levels in HCAEC treated with TGFβ1 +/- the Notch ligand DLL4 (3 μg/ml) in the absence or presence of DAPT (20 μM). Data are mean±SEM, n=3. *p<0.05 vs control (no treatment), #p<0.05 vs TGFβ1 or hypoxia.

Article Snippet: Where indicated, cells were treated with Notch inhibitor DAPT (20 μM, Cat. #2634, Tocris,) or Notch ligand DLL4 (2 μg/ml, Cat. # 1506-D4, R&D Systems).

Techniques: Control

HCAEC were treated with inflammatory cytokines (IL1β + TGFβ1) in the absence or presence of moderate dose ethanol (25 mM EtOH) or high dose ethanol (100 mM EtOH), with or without the gamma secretase inhibitor DAPT (20 μM), before Cdh5 expression was determined by immunocytochemistry. (a) Representative immunofluorescence images from 2 separate experiments, and (b) cumulative quantitative data of Cdh5 fluorescent staining. Data are mean±SEM, n=6. *p<0.05 vs control (no treatment, grp 1), #p<0.05 vs IL1β + TGFβ1 (grp 2).

Journal: bioRxiv

Article Title: A Biphasic Effect of Alcohol on Endothelial Plasticity Through Regulation of Endothelial-to-Mesenchymal Transition

doi: 10.64898/2026.04.14.718463

Figure Lengend Snippet: HCAEC were treated with inflammatory cytokines (IL1β + TGFβ1) in the absence or presence of moderate dose ethanol (25 mM EtOH) or high dose ethanol (100 mM EtOH), with or without the gamma secretase inhibitor DAPT (20 μM), before Cdh5 expression was determined by immunocytochemistry. (a) Representative immunofluorescence images from 2 separate experiments, and (b) cumulative quantitative data of Cdh5 fluorescent staining. Data are mean±SEM, n=6. *p<0.05 vs control (no treatment, grp 1), #p<0.05 vs IL1β + TGFβ1 (grp 2).

Article Snippet: Where indicated, cells were treated with Notch inhibitor DAPT (20 μM, Cat. #2634, Tocris,) or Notch ligand DLL4 (2 μg/ml, Cat. # 1506-D4, R&D Systems).

Techniques: Expressing, Immunocytochemistry, Immunofluorescence, Staining, Control