dapt Search Results


dapt  (Miltenyi Biotec)
92
Miltenyi Biotec dapt
Dapt, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dapt/10__21203_slash_rs__3__rs___4719097_slash_v1-315-49-50?v=Miltenyi+Biotec
Average 92 stars, based on 1 article reviews
dapt - by Bioz Stars, 2026-08
92/100 stars
  Buy from Supplier
3 5 difluorophenacetyl l alanyl s phenylglycine t butyl ester  (StressMarq)
90
StressMarq 3 5 difluorophenacetyl l alanyl s phenylglycine t butyl ester
3 5 Difluorophenacetyl L Alanyl S Phenylglycine T Butyl Ester, supplied by StressMarq, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dapt/pmc04666468-247-3-13?v=StressMarq
Average 90 stars, based on 1 article reviews
3 5 difluorophenacetyl l alanyl s phenylglycine t butyl ester - by Bioz Stars, 2026-08
90/100 stars
  Buy from Supplier
iwp  (Tocris)
96
Tocris iwp
Iwp, supplied by Tocris, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dapt/us12584111-196-2-6?v=Tocris
Average 96 stars, based on 1 article reviews
iwp - by Bioz Stars, 2026-08
96/100 stars
  Buy from Supplier
r04929097  (Selleck Chemicals)
96
Selleck Chemicals r04929097
R04929097, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dapt/us12576135-232-15-16?v=Selleck+Chemicals
Average 96 stars, based on 1 article reviews
r04929097 - by Bioz Stars, 2026-08
96/100 stars
  Buy from Supplier
dapt  (Tocris)
97
Tocris dapt
A) Dot plots representing pathways that are upregulated in hepatocytes cultured in B27 for 7 days post plating. Heatmaps representing normalized expression of genes from (B)Wnt, (C)TGFβ, (D)Notch, (E)BMP and Adenylate cyclase signalling pathways deregulated in cultured vs freshly isolated hepatocytes. The data is scaled and representative of 2 biological replicates of RNA sequencing. The effect of specific host pathway inhibitors <t>(IWP2,</t> <t>SB431542,</t> <t>DAPT,</t> LDN193189 and Forskolin) on respectively schizont numbers (F; each dot is the average count of two technical replicates), size of schizonts (G; each dot is the median of at least 100 schizonts), total DAPI per schizont (H; each dot is the median of at least 100 schizonts), and total PfMSP1 per schizont (I; each dot is the median of at least 100 schizonts) on day 5 p.i.. The grey dotted line (per graphs F-I) shows the median measurements of schizonts grown in B27 control (from four independent experiments). The p-values from a Dunnett’s multiple comparisons test are shown. J) Representative confocal images (from four independent experiments) showing schizonts grown in B27 alone and B27 supplemented with Forskolin, SB431542, IWP2, DAPT and LDN193189 on day 5 p.i. stained with PfMSP1, PfHSP70 and DAPI. Scale bar is 25 microns.
Dapt, supplied by Tocris, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dapt/bio_rxiv__2024__05__07__592925-129-38-39?v=Tocris
Average 97 stars, based on 1 article reviews
dapt - by Bioz Stars, 2026-08
97/100 stars
  Buy from Supplier
embryonic muscle progenitors  (Thermo Fisher)
95
Thermo Fisher embryonic muscle progenitors
A) Dot plots representing pathways that are upregulated in hepatocytes cultured in B27 for 7 days post plating. Heatmaps representing normalized expression of genes from (B)Wnt, (C)TGFβ, (D)Notch, (E)BMP and Adenylate cyclase signalling pathways deregulated in cultured vs freshly isolated hepatocytes. The data is scaled and representative of 2 biological replicates of RNA sequencing. The effect of specific host pathway inhibitors <t>(IWP2,</t> <t>SB431542,</t> <t>DAPT,</t> LDN193189 and Forskolin) on respectively schizont numbers (F; each dot is the average count of two technical replicates), size of schizonts (G; each dot is the median of at least 100 schizonts), total DAPI per schizont (H; each dot is the median of at least 100 schizonts), and total PfMSP1 per schizont (I; each dot is the median of at least 100 schizonts) on day 5 p.i.. The grey dotted line (per graphs F-I) shows the median measurements of schizonts grown in B27 control (from four independent experiments). The p-values from a Dunnett’s multiple comparisons test are shown. J) Representative confocal images (from four independent experiments) showing schizonts grown in B27 alone and B27 supplemented with Forskolin, SB431542, IWP2, DAPT and LDN193189 on day 5 p.i. stained with PfMSP1, PfHSP70 and DAPI. Scale bar is 25 microns.
Embryonic Muscle Progenitors, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dapt/ppr0237339-107-36-78?v=Thermo+Fisher
Average 95 stars, based on 1 article reviews
embryonic muscle progenitors - by Bioz Stars, 2026-08
95/100 stars
  Buy from Supplier
dapt  (Biogems International)
93
Biogems International dapt
A) Dot plots representing pathways that are upregulated in hepatocytes cultured in B27 for 7 days post plating. Heatmaps representing normalized expression of genes from (B)Wnt, (C)TGFβ, (D)Notch, (E)BMP and Adenylate cyclase signalling pathways deregulated in cultured vs freshly isolated hepatocytes. The data is scaled and representative of 2 biological replicates of RNA sequencing. The effect of specific host pathway inhibitors <t>(IWP2,</t> <t>SB431542,</t> <t>DAPT,</t> LDN193189 and Forskolin) on respectively schizont numbers (F; each dot is the average count of two technical replicates), size of schizonts (G; each dot is the median of at least 100 schizonts), total DAPI per schizont (H; each dot is the median of at least 100 schizonts), and total PfMSP1 per schizont (I; each dot is the median of at least 100 schizonts) on day 5 p.i.. The grey dotted line (per graphs F-I) shows the median measurements of schizonts grown in B27 control (from four independent experiments). The p-values from a Dunnett’s multiple comparisons test are shown. J) Representative confocal images (from four independent experiments) showing schizonts grown in B27 alone and B27 supplemented with Forskolin, SB431542, IWP2, DAPT and LDN193189 on day 5 p.i. stained with PfMSP1, PfHSP70 and DAPI. Scale bar is 25 microns.
Dapt, supplied by Biogems International, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dapt/pmc12862199-73-53-54?v=Biogems+International
Average 93 stars, based on 1 article reviews
dapt - by Bioz Stars, 2026-08
93/100 stars
  Buy from Supplier
dapt  (Toronto Research Chemicals)
86
Toronto Research Chemicals dapt
A) Dot plots representing pathways that are upregulated in hepatocytes cultured in B27 for 7 days post plating. Heatmaps representing normalized expression of genes from (B)Wnt, (C)TGFβ, (D)Notch, (E)BMP and Adenylate cyclase signalling pathways deregulated in cultured vs freshly isolated hepatocytes. The data is scaled and representative of 2 biological replicates of RNA sequencing. The effect of specific host pathway inhibitors <t>(IWP2,</t> <t>SB431542,</t> <t>DAPT,</t> LDN193189 and Forskolin) on respectively schizont numbers (F; each dot is the average count of two technical replicates), size of schizonts (G; each dot is the median of at least 100 schizonts), total DAPI per schizont (H; each dot is the median of at least 100 schizonts), and total PfMSP1 per schizont (I; each dot is the median of at least 100 schizonts) on day 5 p.i.. The grey dotted line (per graphs F-I) shows the median measurements of schizonts grown in B27 control (from four independent experiments). The p-values from a Dunnett’s multiple comparisons test are shown. J) Representative confocal images (from four independent experiments) showing schizonts grown in B27 alone and B27 supplemented with Forskolin, SB431542, IWP2, DAPT and LDN193189 on day 5 p.i. stained with PfMSP1, PfHSP70 and DAPI. Scale bar is 25 microns.
Dapt, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dapt/pm27126199-81-6-7?v=Toronto+Research+Chemicals
Average 86 stars, based on 1 article reviews
dapt - by Bioz Stars, 2026-08
86/100 stars
  Buy from Supplier
n n 3 5 difluorophenacetyl l alanyl s phenylglycine t butyl ester  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology n n 3 5 difluorophenacetyl l alanyl s phenylglycine t butyl ester
A) Dot plots representing pathways that are upregulated in hepatocytes cultured in B27 for 7 days post plating. Heatmaps representing normalized expression of genes from (B)Wnt, (C)TGFβ, (D)Notch, (E)BMP and Adenylate cyclase signalling pathways deregulated in cultured vs freshly isolated hepatocytes. The data is scaled and representative of 2 biological replicates of RNA sequencing. The effect of specific host pathway inhibitors <t>(IWP2,</t> <t>SB431542,</t> <t>DAPT,</t> LDN193189 and Forskolin) on respectively schizont numbers (F; each dot is the average count of two technical replicates), size of schizonts (G; each dot is the median of at least 100 schizonts), total DAPI per schizont (H; each dot is the median of at least 100 schizonts), and total PfMSP1 per schizont (I; each dot is the median of at least 100 schizonts) on day 5 p.i.. The grey dotted line (per graphs F-I) shows the median measurements of schizonts grown in B27 control (from four independent experiments). The p-values from a Dunnett’s multiple comparisons test are shown. J) Representative confocal images (from four independent experiments) showing schizonts grown in B27 alone and B27 supplemented with Forskolin, SB431542, IWP2, DAPT and LDN193189 on day 5 p.i. stained with PfMSP1, PfHSP70 and DAPI. Scale bar is 25 microns.
N N 3 5 Difluorophenacetyl L Alanyl S Phenylglycine T Butyl Ester, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dapt/pmc05693650-151-53-58?v=Santa+Cruz+Biotechnology
Average 93 stars, based on 1 article reviews
n n 3 5 difluorophenacetyl l alanyl s phenylglycine t butyl ester - by Bioz Stars, 2026-08
93/100 stars
  Buy from Supplier
dapt kinetic  (Thermo Fisher)
95
Thermo Fisher dapt kinetic
A) Dot plots representing pathways that are upregulated in hepatocytes cultured in B27 for 7 days post plating. Heatmaps representing normalized expression of genes from (B)Wnt, (C)TGFβ, (D)Notch, (E)BMP and Adenylate cyclase signalling pathways deregulated in cultured vs freshly isolated hepatocytes. The data is scaled and representative of 2 biological replicates of RNA sequencing. The effect of specific host pathway inhibitors <t>(IWP2,</t> <t>SB431542,</t> <t>DAPT,</t> LDN193189 and Forskolin) on respectively schizont numbers (F; each dot is the average count of two technical replicates), size of schizonts (G; each dot is the median of at least 100 schizonts), total DAPI per schizont (H; each dot is the median of at least 100 schizonts), and total PfMSP1 per schizont (I; each dot is the median of at least 100 schizonts) on day 5 p.i.. The grey dotted line (per graphs F-I) shows the median measurements of schizonts grown in B27 control (from four independent experiments). The p-values from a Dunnett’s multiple comparisons test are shown. J) Representative confocal images (from four independent experiments) showing schizonts grown in B27 alone and B27 supplemented with Forskolin, SB431542, IWP2, DAPT and LDN193189 on day 5 p.i. stained with PfMSP1, PfHSP70 and DAPI. Scale bar is 25 microns.
Dapt Kinetic, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dapt/pmc13056577-88-1-12?v=Thermo+Fisher
Average 95 stars, based on 1 article reviews
dapt kinetic - by Bioz Stars, 2026-08
95/100 stars
  Buy from Supplier

Image Search Results


A) Dot plots representing pathways that are upregulated in hepatocytes cultured in B27 for 7 days post plating. Heatmaps representing normalized expression of genes from (B)Wnt, (C)TGFβ, (D)Notch, (E)BMP and Adenylate cyclase signalling pathways deregulated in cultured vs freshly isolated hepatocytes. The data is scaled and representative of 2 biological replicates of RNA sequencing. The effect of specific host pathway inhibitors (IWP2, SB431542, DAPT, LDN193189 and Forskolin) on respectively schizont numbers (F; each dot is the average count of two technical replicates), size of schizonts (G; each dot is the median of at least 100 schizonts), total DAPI per schizont (H; each dot is the median of at least 100 schizonts), and total PfMSP1 per schizont (I; each dot is the median of at least 100 schizonts) on day 5 p.i.. The grey dotted line (per graphs F-I) shows the median measurements of schizonts grown in B27 control (from four independent experiments). The p-values from a Dunnett’s multiple comparisons test are shown. J) Representative confocal images (from four independent experiments) showing schizonts grown in B27 alone and B27 supplemented with Forskolin, SB431542, IWP2, DAPT and LDN193189 on day 5 p.i. stained with PfMSP1, PfHSP70 and DAPI. Scale bar is 25 microns.

Journal: bioRxiv

Article Title: Modulation of host signalling pathways reveal a major role for Wnt signalling in the maturation of Plasmodium falciparum liver schizonts

doi: 10.1101/2024.05.07.592925

Figure Lengend Snippet: A) Dot plots representing pathways that are upregulated in hepatocytes cultured in B27 for 7 days post plating. Heatmaps representing normalized expression of genes from (B)Wnt, (C)TGFβ, (D)Notch, (E)BMP and Adenylate cyclase signalling pathways deregulated in cultured vs freshly isolated hepatocytes. The data is scaled and representative of 2 biological replicates of RNA sequencing. The effect of specific host pathway inhibitors (IWP2, SB431542, DAPT, LDN193189 and Forskolin) on respectively schizont numbers (F; each dot is the average count of two technical replicates), size of schizonts (G; each dot is the median of at least 100 schizonts), total DAPI per schizont (H; each dot is the median of at least 100 schizonts), and total PfMSP1 per schizont (I; each dot is the median of at least 100 schizonts) on day 5 p.i.. The grey dotted line (per graphs F-I) shows the median measurements of schizonts grown in B27 control (from four independent experiments). The p-values from a Dunnett’s multiple comparisons test are shown. J) Representative confocal images (from four independent experiments) showing schizonts grown in B27 alone and B27 supplemented with Forskolin, SB431542, IWP2, DAPT and LDN193189 on day 5 p.i. stained with PfMSP1, PfHSP70 and DAPI. Scale bar is 25 microns.

Article Snippet: The following day, it was changed to the following medium conditions: B27 or B27 supplemented with 20μM of Forskolin (Enzo Life Sciences: BML-CN100-0010), or 10μM of SB431542 (Tocris: 1614), or 0.5μM of IWP2 (Tocris: 3533), or 5μM of DAPT (Tocris: 2634) or 0.1μM of LDN193189 (Tocris: 6053) or the combination of all the compound inhibitors (i.e. 5C).

Techniques: Cell Culture, Expressing, Isolation, RNA Sequencing, Control, Staining