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TSF and Rg3 alleviates DOX‐induced myocardial injury (a) Alterations in high‐frequency echocardiography in mouse heart tissue. (b) HE staining of heart tissues (Scale bar = 50 μm, magnification ×200). (c) The changes in the content <t>of</t> <t>CK‐MB</t> in each group. Data were collected from eight mice per group and are presented as the mean and standard. Data analysis among groups was performed using ANOVA, with LSD for equal variances and Dunnett's‐T3 for unequal variances, with significance levels of * p < 0.05, ** p < 0.01, *** p < 0.001.
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TSF and Rg3 alleviates DOX‐induced myocardial injury (a) Alterations in high‐frequency echocardiography in mouse heart tissue. (b) HE staining of heart tissues (Scale bar = 50 μm, magnification ×200). (c) The changes in the content <t>of</t> <t>CK‐MB</t> in each group. Data were collected from eight mice per group and are presented as the mean and standard. Data analysis among groups was performed using ANOVA, with LSD for equal variances and Dunnett's‐T3 for unequal variances, with significance levels of * p < 0.05, ** p < 0.01, *** p < 0.001.
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TSF and Rg3 alleviates DOX‐induced myocardial injury (a) Alterations in high‐frequency echocardiography in mouse heart tissue. (b) HE staining of heart tissues (Scale bar = 50 μm, magnification ×200). (c) The changes in the content <t>of</t> <t>CK‐MB</t> in each group. Data were collected from eight mice per group and are presented as the mean and standard. Data analysis among groups was performed using ANOVA, with LSD for equal variances and Dunnett's‐T3 for unequal variances, with significance levels of * p < 0.05, ** p < 0.01, *** p < 0.001.
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TSF and Rg3 alleviates DOX‐induced myocardial injury (a) Alterations in high‐frequency echocardiography in mouse heart tissue. (b) HE staining of heart tissues (Scale bar = 50 μm, magnification ×200). (c) The changes in the content <t>of</t> <t>CK‐MB</t> in each group. Data were collected from eight mice per group and are presented as the mean and standard. Data analysis among groups was performed using ANOVA, with LSD for equal variances and Dunnett's‐T3 for unequal variances, with significance levels of * p < 0.05, ** p < 0.01, *** p < 0.001.
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TSF and Rg3 alleviates DOX‐induced myocardial injury (a) Alterations in high‐frequency echocardiography in mouse heart tissue. (b) HE staining of heart tissues (Scale bar = 50 μm, magnification ×200). (c) The changes in the content <t>of</t> <t>CK‐MB</t> in each group. Data were collected from eight mice per group and are presented as the mean and standard. Data analysis among groups was performed using ANOVA, with LSD for equal variances and Dunnett's‐T3 for unequal variances, with significance levels of * p < 0.05, ** p < 0.01, *** p < 0.001.
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TSF and Rg3 alleviates DOX‐induced myocardial injury (a) Alterations in high‐frequency echocardiography in mouse heart tissue. (b) HE staining of heart tissues (Scale bar = 50 μm, magnification ×200). (c) The changes in the content <t>of</t> <t>CK‐MB</t> in each group. Data were collected from eight mice per group and are presented as the mean and standard. Data analysis among groups was performed using ANOVA, with LSD for equal variances and Dunnett's‐T3 for unequal variances, with significance levels of * p < 0.05, ** p < 0.01, *** p < 0.001.
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TSF and Rg3 alleviates DOX‐induced myocardial injury (a) Alterations in high‐frequency echocardiography in mouse heart tissue. (b) HE staining of heart tissues (Scale bar = 50 μm, magnification ×200). (c) The changes in the content <t>of</t> <t>CK‐MB</t> in each group. Data were collected from eight mice per group and are presented as the mean and standard. Data analysis among groups was performed using ANOVA, with LSD for equal variances and Dunnett's‐T3 for unequal variances, with significance levels of * p < 0.05, ** p < 0.01, *** p < 0.001.
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TSF and Rg3 alleviates DOX‐induced myocardial injury (a) Alterations in high‐frequency echocardiography in mouse heart tissue. (b) HE staining of heart tissues (Scale bar = 50 μm, magnification ×200). (c) The changes in the content <t>of</t> <t>CK‐MB</t> in each group. Data were collected from eight mice per group and are presented as the mean and standard. Data analysis among groups was performed using ANOVA, with LSD for equal variances and Dunnett's‐T3 for unequal variances, with significance levels of * p < 0.05, ** p < 0.01, *** p < 0.001.
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TSF and Rg3 alleviates DOX‐induced myocardial injury (a) Alterations in high‐frequency echocardiography in mouse heart tissue. (b) HE staining of heart tissues (Scale bar = 50 μm, magnification ×200). (c) The changes in the content of CK‐MB in each group. Data were collected from eight mice per group and are presented as the mean and standard. Data analysis among groups was performed using ANOVA, with LSD for equal variances and Dunnett's‐T3 for unequal variances, with significance levels of * p < 0.05, ** p < 0.01, *** p < 0.001.

Journal: Food Science & Nutrition

Article Title: Exploring the Mechanisms of Total Saponins of Black Ginseng and Ginsenoside Rg3 Against Doxorubicin‐Induced Cardiotoxicity

doi: 10.1002/fsn3.71968

Figure Lengend Snippet: TSF and Rg3 alleviates DOX‐induced myocardial injury (a) Alterations in high‐frequency echocardiography in mouse heart tissue. (b) HE staining of heart tissues (Scale bar = 50 μm, magnification ×200). (c) The changes in the content of CK‐MB in each group. Data were collected from eight mice per group and are presented as the mean and standard. Data analysis among groups was performed using ANOVA, with LSD for equal variances and Dunnett's‐T3 for unequal variances, with significance levels of * p < 0.05, ** p < 0.01, *** p < 0.001.

Article Snippet: While kits for Creatine kinase‐MB (CK‐MB), superoxide dismutase (SOD), malonaldehyde (MDA), and Adeno‐sine 5 triphosphate (ATP) were procured from Nanjing Jiancheng Bioengineering Institute, China (Lot: 20240925、20240927、20241009、20240927).

Techniques: Staining