Review



yes1  (Bioss)


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    Structured Review

    Bioss yes1
    Up and down-regulation of all significantly changed organ damage-related proteins during HOPE. ( A ) SMAD1; mothers against decapentaplegic homolog 1, ( B ) ALDH3A1; aldehyde dehydrogenase, dimeric NADP-preferring, ( C ) TOP2B; DNA topoisomerase 2-beta, ( D ) PGF; placenta growth factor, ( E ) ENAH; protein enabled homolog, ( F ) FES; tyrosine-protein kinase Fes/Fps, ( G ) LTA4H; leukotriene A-4 hydrolase, ( H ) FOXO1; forkhead box protein O1, ( I ) CA12; carbonic anhydrase 12, ( J ) PLIN1; perilipin-1, ( K ) <t>YES1;</t> tyrosine-protein kinase Yes, ( L ) MAEA; macrophage erythroblast attacher, ( M ) MAGED1; melanoma-associated antigen D1, ( N ) MAX; protein max, ( O ) FOSB; protein fosB. *, non-adjusted p value of less than 0.05; HOPE, hypothermic machine perfusion; NPX, normalized protein expression; T, time in minutes.
    Yes1, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/yes1/product/Bioss
    Average 94 stars, based on 2 article reviews
    yes1 - by Bioz Stars, 2026-02
    94/100 stars

    Images

    1) Product Images from "Candidate Biomarkers YES1, Troponin I, Lactate, and Ammonia for Evaluation of Cardiac Function Post Hypothermic Oxygenated Perfusion"

    Article Title: Candidate Biomarkers YES1, Troponin I, Lactate, and Ammonia for Evaluation of Cardiac Function Post Hypothermic Oxygenated Perfusion

    Journal: Asaio Journal

    doi: 10.1097/MAT.0000000000002419

    Up and down-regulation of all significantly changed organ damage-related proteins during HOPE. ( A ) SMAD1; mothers against decapentaplegic homolog 1, ( B ) ALDH3A1; aldehyde dehydrogenase, dimeric NADP-preferring, ( C ) TOP2B; DNA topoisomerase 2-beta, ( D ) PGF; placenta growth factor, ( E ) ENAH; protein enabled homolog, ( F ) FES; tyrosine-protein kinase Fes/Fps, ( G ) LTA4H; leukotriene A-4 hydrolase, ( H ) FOXO1; forkhead box protein O1, ( I ) CA12; carbonic anhydrase 12, ( J ) PLIN1; perilipin-1, ( K ) YES1; tyrosine-protein kinase Yes, ( L ) MAEA; macrophage erythroblast attacher, ( M ) MAGED1; melanoma-associated antigen D1, ( N ) MAX; protein max, ( O ) FOSB; protein fosB. *, non-adjusted p value of less than 0.05; HOPE, hypothermic machine perfusion; NPX, normalized protein expression; T, time in minutes.
    Figure Legend Snippet: Up and down-regulation of all significantly changed organ damage-related proteins during HOPE. ( A ) SMAD1; mothers against decapentaplegic homolog 1, ( B ) ALDH3A1; aldehyde dehydrogenase, dimeric NADP-preferring, ( C ) TOP2B; DNA topoisomerase 2-beta, ( D ) PGF; placenta growth factor, ( E ) ENAH; protein enabled homolog, ( F ) FES; tyrosine-protein kinase Fes/Fps, ( G ) LTA4H; leukotriene A-4 hydrolase, ( H ) FOXO1; forkhead box protein O1, ( I ) CA12; carbonic anhydrase 12, ( J ) PLIN1; perilipin-1, ( K ) YES1; tyrosine-protein kinase Yes, ( L ) MAEA; macrophage erythroblast attacher, ( M ) MAGED1; melanoma-associated antigen D1, ( N ) MAX; protein max, ( O ) FOSB; protein fosB. *, non-adjusted p value of less than 0.05; HOPE, hypothermic machine perfusion; NPX, normalized protein expression; T, time in minutes.

    Techniques Used: Expressing

    YES1 antibody-positive stained cardiac tissue during hypothermic and normothermic machine perfusion over time. Representative YES1 immunohistochemistry images of three porcine hearts ( A–J ) depict a heterogeneous staining pattern. At baseline (T0; A,D,G ), after 4 hours of HOPE (T4; B,E,H ) and at the end of 4 hours NMP (T240; C,F,J ), YES1 is localized in the cytoplasm of endothelial cells and cardiomyocytes with varying intensity. The tissue architecture in these slides remains intact throughout HOPE and NMP.
    Figure Legend Snippet: YES1 antibody-positive stained cardiac tissue during hypothermic and normothermic machine perfusion over time. Representative YES1 immunohistochemistry images of three porcine hearts ( A–J ) depict a heterogeneous staining pattern. At baseline (T0; A,D,G ), after 4 hours of HOPE (T4; B,E,H ) and at the end of 4 hours NMP (T240; C,F,J ), YES1 is localized in the cytoplasm of endothelial cells and cardiomyocytes with varying intensity. The tissue architecture in these slides remains intact throughout HOPE and NMP.

    Techniques Used: Staining, Immunohistochemistry



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