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rabbit anti human p16  (Bioss)


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    Structured Review

    Bioss rabbit anti human p16
    Immunohistochemical examination for <t>P16</t> in (A) chronic cervicitis, (B) low-grade squamous intraepithelial lesion, (C) high-grade squamous intraepithelial lesion and (D) cervical squamous cell carcinoma. Red arrows indicate P16 positive staining (brown-yellow granules) in the cytoplasm and nucleus. Magnification, ×200. Scale bars represent 50 µm.
    Rabbit Anti Human P16, supplied by Bioss, used in various techniques. Bioz Stars score: 90/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti human p16/product/Bioss
    Average 90 stars, based on 2 article reviews
    rabbit anti human p16 - by Bioz Stars, 2026-02
    90/100 stars

    Images

    1) Product Images from "Associations between the expression of SCCA, MTA1, P16, Ki-67 and the infection of high-risk HPV in cervical lesions"

    Article Title: Associations between the expression of SCCA, MTA1, P16, Ki-67 and the infection of high-risk HPV in cervical lesions

    Journal: Oncology Letters

    doi: 10.3892/ol.2020.11634

    Immunohistochemical examination for P16 in (A) chronic cervicitis, (B) low-grade squamous intraepithelial lesion, (C) high-grade squamous intraepithelial lesion and (D) cervical squamous cell carcinoma. Red arrows indicate P16 positive staining (brown-yellow granules) in the cytoplasm and nucleus. Magnification, ×200. Scale bars represent 50 µm.
    Figure Legend Snippet: Immunohistochemical examination for P16 in (A) chronic cervicitis, (B) low-grade squamous intraepithelial lesion, (C) high-grade squamous intraepithelial lesion and (D) cervical squamous cell carcinoma. Red arrows indicate P16 positive staining (brown-yellow granules) in the cytoplasm and nucleus. Magnification, ×200. Scale bars represent 50 µm.

    Techniques Used: Immunohistochemical staining, Staining

    Immunohistochemical examination for P16 protein in cervical tissues from the CCE, LSIL, HSIL and CSCC groups.
    Figure Legend Snippet: Immunohistochemical examination for P16 protein in cervical tissues from the CCE, LSIL, HSIL and CSCC groups.

    Techniques Used: Immunohistochemical staining

    The expression of the four analyzed proteins and infection of HR-HPV in cervical tissues.
    Figure Legend Snippet: The expression of the four analyzed proteins and infection of HR-HPV in cervical tissues.

    Techniques Used: Expressing, Infection



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    rabbit anti human p16  (Bioss)
    90
    Bioss rabbit anti human p16
    Immunohistochemical examination for <t>P16</t> in (A) chronic cervicitis, (B) low-grade squamous intraepithelial lesion, (C) high-grade squamous intraepithelial lesion and (D) cervical squamous cell carcinoma. Red arrows indicate P16 positive staining (brown-yellow granules) in the cytoplasm and nucleus. Magnification, ×200. Scale bars represent 50 µm.
    Rabbit Anti Human P16, supplied by Bioss, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti human p16/product/Bioss
    Average 90 stars, based on 1 article reviews
    rabbit anti human p16 - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    mmp-16 (bs-1856r)  (Thermo Fisher)
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    SPOCK1 regulates motility via inducing matrix metalloproteinase <t>(MMP)-14/MMP-16-mediated</t> MMP-2 activation in clear cell renal cell carcinoma (ccRCC) cells. ( A ) SPOCK1 protein–protein interaction network of 10 differentially expressed genes from the STRING database. ( B ) Caki-1 and 786-O cells were infected with a lentivirus carrying either SPOCK1 shRNA or shCtrl and subjected to a Western blot analysis to determine expressions of MMP-16, MMP-14, MMP-9, MMP-3, and MMP-2. ( C ) Treatment of Caki-1 cells with or without the recombinant SPOCK1 protein (rSPOCK1, 1 ng/mL) for 24 and 48 h, and expressions of MMP-16, MMP-14, and MMP-2 were detected by Western blotting. Quantitative results of indicated MMP proteins were adjusted to GAPDH protein levels. ( D ) MMP-2 activity of SPOCK1-overexpressing Caki-1 and 786-O cells was detected by a gelatin zymographic assay. ( E ) An MMP-2-expressing plasmid was transfected into Caki-1 cells expressing shCtrl or shSPOCK1 as indicated and subjected to transwell invasion assays. Top: Representative photomicrographs. Bottom: Quantitative results of the invasion assay are shown. *** p < 0.001, compared to the control group. ## p < 0.01 compared to the SPOCK1-KD only group. ( F ) Correlation analysis of the KIRC database (TCGA, PanCancer Atlas) using cBioPortal revealed positive correlations of SPOCK1 or MMP2 with mRNA levels of the indicated MMP genes. ( G ) Combined expressions of high SPOCK1 and high MMP14, MMP16, or MMP2 were correlated with the overall survival of patients with ccRCC. The p value refers to a comparison between SPOCK1 high /MMP high and other groups (SPOCK high /MMP low , SPOCK low /MMP high , or SPOCK low /MMP low ).
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    anti‑human p16  (Bioss)
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    SPOCK1 regulates motility via inducing matrix metalloproteinase <t>(MMP)-14/MMP-16-mediated</t> MMP-2 activation in clear cell renal cell carcinoma (ccRCC) cells. ( A ) SPOCK1 protein–protein interaction network of 10 differentially expressed genes from the STRING database. ( B ) Caki-1 and 786-O cells were infected with a lentivirus carrying either SPOCK1 shRNA or shCtrl and subjected to a Western blot analysis to determine expressions of MMP-16, MMP-14, MMP-9, MMP-3, and MMP-2. ( C ) Treatment of Caki-1 cells with or without the recombinant SPOCK1 protein (rSPOCK1, 1 ng/mL) for 24 and 48 h, and expressions of MMP-16, MMP-14, and MMP-2 were detected by Western blotting. Quantitative results of indicated MMP proteins were adjusted to GAPDH protein levels. ( D ) MMP-2 activity of SPOCK1-overexpressing Caki-1 and 786-O cells was detected by a gelatin zymographic assay. ( E ) An MMP-2-expressing plasmid was transfected into Caki-1 cells expressing shCtrl or shSPOCK1 as indicated and subjected to transwell invasion assays. Top: Representative photomicrographs. Bottom: Quantitative results of the invasion assay are shown. *** p < 0.001, compared to the control group. ## p < 0.01 compared to the SPOCK1-KD only group. ( F ) Correlation analysis of the KIRC database (TCGA, PanCancer Atlas) using cBioPortal revealed positive correlations of SPOCK1 or MMP2 with mRNA levels of the indicated MMP genes. ( G ) Combined expressions of high SPOCK1 and high MMP14, MMP16, or MMP2 were correlated with the overall survival of patients with ccRCC. The p value refers to a comparison between SPOCK1 high /MMP high and other groups (SPOCK high /MMP low , SPOCK low /MMP high , or SPOCK low /MMP low ).
    Anti‑Human P16, supplied by Bioss, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti‑human p16/product/Bioss
    Average 90 stars, based on 1 article reviews
    anti‑human p16 - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Immunohistochemical examination for P16 in (A) chronic cervicitis, (B) low-grade squamous intraepithelial lesion, (C) high-grade squamous intraepithelial lesion and (D) cervical squamous cell carcinoma. Red arrows indicate P16 positive staining (brown-yellow granules) in the cytoplasm and nucleus. Magnification, ×200. Scale bars represent 50 µm.

    Journal: Oncology Letters

    Article Title: Associations between the expression of SCCA, MTA1, P16, Ki-67 and the infection of high-risk HPV in cervical lesions

    doi: 10.3892/ol.2020.11634

    Figure Lengend Snippet: Immunohistochemical examination for P16 in (A) chronic cervicitis, (B) low-grade squamous intraepithelial lesion, (C) high-grade squamous intraepithelial lesion and (D) cervical squamous cell carcinoma. Red arrows indicate P16 positive staining (brown-yellow granules) in the cytoplasm and nucleus. Magnification, ×200. Scale bars represent 50 µm.

    Article Snippet: All sections were incubated separately with the following primary antibodies: Rabbit anti-human SCCA (1:600; cat. no. A6960ABclonal Biotech Co., Ltd.), rabbit anti-human MTA1 (1:600; cat. no. A16085; ABclonal Biotech Co., Ltd.), rabbit anti-human Ki-67 (1:600; cat. no. bs-23103R; Bioss Inc.) or rabbit anti-human P16 (1:600; cat. no. bs-1856R; Bioss Inc.) at 4°C overnight, followed by incubation with goat anti-rabbit horseradish peroxidase labelled immunoglobulin (IgG-HRP) secondary antibodies (1:2,000, cat. no. sc2030; Santa Cruz Biotechnology Inc.) at 37°C for 40 min.

    Techniques: Immunohistochemical staining, Staining

    Immunohistochemical examination for P16 protein in cervical tissues from the CCE, LSIL, HSIL and CSCC groups.

    Journal: Oncology Letters

    Article Title: Associations between the expression of SCCA, MTA1, P16, Ki-67 and the infection of high-risk HPV in cervical lesions

    doi: 10.3892/ol.2020.11634

    Figure Lengend Snippet: Immunohistochemical examination for P16 protein in cervical tissues from the CCE, LSIL, HSIL and CSCC groups.

    Article Snippet: All sections were incubated separately with the following primary antibodies: Rabbit anti-human SCCA (1:600; cat. no. A6960ABclonal Biotech Co., Ltd.), rabbit anti-human MTA1 (1:600; cat. no. A16085; ABclonal Biotech Co., Ltd.), rabbit anti-human Ki-67 (1:600; cat. no. bs-23103R; Bioss Inc.) or rabbit anti-human P16 (1:600; cat. no. bs-1856R; Bioss Inc.) at 4°C overnight, followed by incubation with goat anti-rabbit horseradish peroxidase labelled immunoglobulin (IgG-HRP) secondary antibodies (1:2,000, cat. no. sc2030; Santa Cruz Biotechnology Inc.) at 37°C for 40 min.

    Techniques: Immunohistochemical staining

    The expression of the four analyzed proteins and infection of HR-HPV in cervical tissues.

    Journal: Oncology Letters

    Article Title: Associations between the expression of SCCA, MTA1, P16, Ki-67 and the infection of high-risk HPV in cervical lesions

    doi: 10.3892/ol.2020.11634

    Figure Lengend Snippet: The expression of the four analyzed proteins and infection of HR-HPV in cervical tissues.

    Article Snippet: All sections were incubated separately with the following primary antibodies: Rabbit anti-human SCCA (1:600; cat. no. A6960ABclonal Biotech Co., Ltd.), rabbit anti-human MTA1 (1:600; cat. no. A16085; ABclonal Biotech Co., Ltd.), rabbit anti-human Ki-67 (1:600; cat. no. bs-23103R; Bioss Inc.) or rabbit anti-human P16 (1:600; cat. no. bs-1856R; Bioss Inc.) at 4°C overnight, followed by incubation with goat anti-rabbit horseradish peroxidase labelled immunoglobulin (IgG-HRP) secondary antibodies (1:2,000, cat. no. sc2030; Santa Cruz Biotechnology Inc.) at 37°C for 40 min.

    Techniques: Expressing, Infection

    SPOCK1 regulates motility via inducing matrix metalloproteinase (MMP)-14/MMP-16-mediated MMP-2 activation in clear cell renal cell carcinoma (ccRCC) cells. ( A ) SPOCK1 protein–protein interaction network of 10 differentially expressed genes from the STRING database. ( B ) Caki-1 and 786-O cells were infected with a lentivirus carrying either SPOCK1 shRNA or shCtrl and subjected to a Western blot analysis to determine expressions of MMP-16, MMP-14, MMP-9, MMP-3, and MMP-2. ( C ) Treatment of Caki-1 cells with or without the recombinant SPOCK1 protein (rSPOCK1, 1 ng/mL) for 24 and 48 h, and expressions of MMP-16, MMP-14, and MMP-2 were detected by Western blotting. Quantitative results of indicated MMP proteins were adjusted to GAPDH protein levels. ( D ) MMP-2 activity of SPOCK1-overexpressing Caki-1 and 786-O cells was detected by a gelatin zymographic assay. ( E ) An MMP-2-expressing plasmid was transfected into Caki-1 cells expressing shCtrl or shSPOCK1 as indicated and subjected to transwell invasion assays. Top: Representative photomicrographs. Bottom: Quantitative results of the invasion assay are shown. *** p < 0.001, compared to the control group. ## p < 0.01 compared to the SPOCK1-KD only group. ( F ) Correlation analysis of the KIRC database (TCGA, PanCancer Atlas) using cBioPortal revealed positive correlations of SPOCK1 or MMP2 with mRNA levels of the indicated MMP genes. ( G ) Combined expressions of high SPOCK1 and high MMP14, MMP16, or MMP2 were correlated with the overall survival of patients with ccRCC. The p value refers to a comparison between SPOCK1 high /MMP high and other groups (SPOCK high /MMP low , SPOCK low /MMP high , or SPOCK low /MMP low ).

    Journal: Cells

    Article Title: Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition

    doi: 10.3390/cells12030352

    Figure Lengend Snippet: SPOCK1 regulates motility via inducing matrix metalloproteinase (MMP)-14/MMP-16-mediated MMP-2 activation in clear cell renal cell carcinoma (ccRCC) cells. ( A ) SPOCK1 protein–protein interaction network of 10 differentially expressed genes from the STRING database. ( B ) Caki-1 and 786-O cells were infected with a lentivirus carrying either SPOCK1 shRNA or shCtrl and subjected to a Western blot analysis to determine expressions of MMP-16, MMP-14, MMP-9, MMP-3, and MMP-2. ( C ) Treatment of Caki-1 cells with or without the recombinant SPOCK1 protein (rSPOCK1, 1 ng/mL) for 24 and 48 h, and expressions of MMP-16, MMP-14, and MMP-2 were detected by Western blotting. Quantitative results of indicated MMP proteins were adjusted to GAPDH protein levels. ( D ) MMP-2 activity of SPOCK1-overexpressing Caki-1 and 786-O cells was detected by a gelatin zymographic assay. ( E ) An MMP-2-expressing plasmid was transfected into Caki-1 cells expressing shCtrl or shSPOCK1 as indicated and subjected to transwell invasion assays. Top: Representative photomicrographs. Bottom: Quantitative results of the invasion assay are shown. *** p < 0.001, compared to the control group. ## p < 0.01 compared to the SPOCK1-KD only group. ( F ) Correlation analysis of the KIRC database (TCGA, PanCancer Atlas) using cBioPortal revealed positive correlations of SPOCK1 or MMP2 with mRNA levels of the indicated MMP genes. ( G ) Combined expressions of high SPOCK1 and high MMP14, MMP16, or MMP2 were correlated with the overall survival of patients with ccRCC. The p value refers to a comparison between SPOCK1 high /MMP high and other groups (SPOCK high /MMP low , SPOCK low /MMP high , or SPOCK low /MMP low ).

    Article Snippet: The antibodies we used were as follows: SPOCK1 (HPA007450), β-actin (A5441) (Sigma-Aldrich); E-cadherin (#3195), N-cadherin (#13116), vimentin (#5741), Snail (#3879), Slug (#9585), MMP-3 (#14351), MMP-2 (#4022), phosphorylated (p)-Akt (#9271) (Cell Signaling Technology, Danvers, MA, USA); MMP-9 (GTX100458) (Genetex, Hsinchu, Taiwan); MMP-14 (sc-377097) (Santa Cruz Biotechnology, Santa Cruz, CA, USA); MMP-16 (bs-1856R) (Thermo Fisher Scientific, Rockford, IL, USA); GAPDH (60004-1-Ig) (Proteintech, Rosemont, IL, USA).

    Techniques: Activation Assay, Infection, shRNA, Western Blot, Recombinant, Activity Assay, Expressing, Plasmid Preparation, Transfection, Invasion Assay