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pkr  (Bioss)


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    Structured Review

    Bioss pkr
    Schematic overview of the proposed mechanism whereby anti-β 2 GPI/β 2 GPI interactions drive neutrophil pyroptosis and associated IL-1β <t>and</t> <t>HMGB1</t> release, thereby causing endothelial cell activation. TLR4, Toll-like receptor 4; NLRP3, NLR family pyrin domain containing 3; anti-β2GPI, anti-β2-glycoprotein I; GSDMD, gasdermin D; <t>PKR,</t> double-stranded RNA-dependent protein kinase; HMGB1, high mobility group box protein 1; ICAM-1, intercellular adhesion molecule-1.
    Pkr, supplied by Bioss, used in various techniques. Bioz Stars score: 91/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pkr/product/Bioss
    Average 91 stars, based on 2 article reviews
    pkr - by Bioz Stars, 2026-02
    91/100 stars

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    1) Product Images from "Anti-β 2 GPI/β 2 GPI induces neutrophil pyroptosis and thereby enhances ICAM-1 and IL-8 expression in endothelial cells"

    Article Title: Anti-β 2 GPI/β 2 GPI induces neutrophil pyroptosis and thereby enhances ICAM-1 and IL-8 expression in endothelial cells

    Journal: International Journal of Molecular Medicine

    doi: 10.3892/ijmm.2022.5120

    Schematic overview of the proposed mechanism whereby anti-β 2 GPI/β 2 GPI interactions drive neutrophil pyroptosis and associated IL-1β and HMGB1 release, thereby causing endothelial cell activation. TLR4, Toll-like receptor 4; NLRP3, NLR family pyrin domain containing 3; anti-β2GPI, anti-β2-glycoprotein I; GSDMD, gasdermin D; PKR, double-stranded RNA-dependent protein kinase; HMGB1, high mobility group box protein 1; ICAM-1, intercellular adhesion molecule-1.
    Figure Legend Snippet: Schematic overview of the proposed mechanism whereby anti-β 2 GPI/β 2 GPI interactions drive neutrophil pyroptosis and associated IL-1β and HMGB1 release, thereby causing endothelial cell activation. TLR4, Toll-like receptor 4; NLRP3, NLR family pyrin domain containing 3; anti-β2GPI, anti-β2-glycoprotein I; GSDMD, gasdermin D; PKR, double-stranded RNA-dependent protein kinase; HMGB1, high mobility group box protein 1; ICAM-1, intercellular adhesion molecule-1.

    Techniques Used: Activation Assay



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