8 bromo camp (MedChemExpress)
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8 bromo camp
8 Bromo Camp, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 37 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bromo/8-Bromo-cAMP/pmc13430265-84-20-23
Average 95 stars, based on 37 article reviews
8 Bromo Camp, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 37 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bromo/8-Bromo-cAMP/pmc13430265-84-20-23
Average 95 stars, based on 37 article reviews
8 bromo camp - by Bioz Stars,
2026-09
95/100 stars
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1) Product Images from "BK channel deficiency promotes lipolysis via an AKT-independent activation of the cAMP/PKA/HSL pathway"
Article Title: BK channel deficiency promotes lipolysis via an AKT-independent activation of the cAMP/PKA/HSL pathway
Journal: Journal of Lipid Research
doi: 10.1016/j.jlr.2026.101094
Figure Legend Snippet: BK channel deficiency enhances lipolysis via the cAMP/PKA/HSL signaling pathway. A and B: Representative western blots (A) and quantitative analysis (B) of PKA substrate phosphorylation levels in eWAT from the indicated mouse models (n = 5). C: Glycerol release from adipocytes measured under basal conditions or following stimulation with 1 μM CL-316243 for 1 h. Cells were preincubated with or without the PKA inhibitor H89 (10 μM) for 1 h prior to stimulation (n = 6). D and E: Representative western blots (D) and quantitative analysis (E) of the phosphorylation levels of key lipolytic regulatory proteins in adipocytes following the indicated treatments (n = 5). F: Glycerol release from mature adipocytes treated with 10 μM forskolin or 1 mM 8-bromo-cAMP for 1 h, measured using a glycerol assay kit (n = 4). G and H: Representative western blots (G) and quantitative analysis (H) of lipolysis-related protein phosphorylation levels in mature adipocytes treated as described in (F) (n = 4). I and J: The average (I) and Δfold change in fluo-4 fluorescence intensity (J) in mature adipocytes treated with 1 μM CL-316243 (n = 4). Data are presented as mean ± SEM. Statistical analysis was performed using an unpaired two-tailed Student's t test for (E, H), Mann–Whitney U test for (B and C, F) and the Kruskal–Wallis test with Dunn's multiple comparisons test for (J). ∗ P < 0.05, ∗∗ P < 0.01, ∗∗∗ P < 0.001, ∗∗∗∗ P < 0.0001. ns, not significant.
Techniques Used: Western Blot, Phospho-proteomics, Fluorescence, Two Tailed Test, MANN-WHITNEY
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