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bp3  (MedChemExpress)


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    Structured Review

    MedChemExpress bp3
    Bp3, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/bp3/PROTAC+HSP90+degrader+BP3/bio_rxiv__64898__2026__06__01__729344-186-17-18
    Average 94 stars, based on 1 article reviews
    bp3 - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    Inhibition:

    Article Title: Distinct Proteasomal Pathways Drive Oncogenic PPM1D Activation
    Article Snippet: For degradation assay, cells were pre-treated with DMSO, 10 μM MG132 (Selleck, S2619), or 1 μM TAK-243 (MedChemExpress, HY-100487) for 1 hour, then with or without 50 μg/mL cycloheximide (Selleck, S7418) for the indicated time. .. For HSP90 and HSP70 inhibition assay, cells were treated with 0.5 μM SNX-2112 (Selleck, S2639), 1 μM BP3 (MedChemExpress, HY-115997), 0.5 μM Ganetespib (Selleck, S1159), 1 μM Tanespimycin (Selleck, S1141), 1 μM BIIB021 (Selleck, S1175), or 20 μM VER-155008 (Selleck, S7751) for 24 hours. .. Alt-R sgRNAs targeting PPM1D , Alt-R HDR donor oligo to reverse the truncated PPM1D allele to full-length PPM1D , and Cas9-GFP nuclease (IDT, 10008100) were introduced to U2OS parental cells according to manufacturer’s protocol using Cell Line Nucleofector Kit V (Lonza, VCA-1003) on a Nucleofector 2b device.

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