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Orchiectomy-induced changes in body composition and adipokines. Body weight (kg) (A), lean mass (kg) (B), fat mass (kg) (C), total fat (%) (D), trunk fat (%) (E), fasted <t>adiponectin</t> (F), and fasted leptin (G) were measured at baseline and up to 15 m post-orchiectomy. Data are expressed as mean ± SEM. * p < .05 by repeated measures one-way ANOVA with Tukey’s multiple comparisons test. Correlation was determined by Pearson’s correlation coefficient between 15 m fat mass change (kg) vs baseline and 15 m leptin (ng/mL) change vs baseline (H).
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Orchiectomy-induced changes in body composition and adipokines. Body weight (kg) (A), lean mass (kg) (B), fat mass (kg) (C), total fat (%) (D), trunk fat (%) (E), fasted adiponectin (F), and fasted leptin (G) were measured at baseline and up to 15 m post-orchiectomy. Data are expressed as mean ± SEM. * p < .05 by repeated measures one-way ANOVA with Tukey’s multiple comparisons test. Correlation was determined by Pearson’s correlation coefficient between 15 m fat mass change (kg) vs baseline and 15 m leptin (ng/mL) change vs baseline (H).

Journal: JBMR Plus

Article Title: Skeletal and body composition effects of orchiectomy in a colony of diet-induced obese cynomolgus macaques

doi: 10.1093/jbmrpl/ziag150

Figure Lengend Snippet: Orchiectomy-induced changes in body composition and adipokines. Body weight (kg) (A), lean mass (kg) (B), fat mass (kg) (C), total fat (%) (D), trunk fat (%) (E), fasted adiponectin (F), and fasted leptin (G) were measured at baseline and up to 15 m post-orchiectomy. Data are expressed as mean ± SEM. * p < .05 by repeated measures one-way ANOVA with Tukey’s multiple comparisons test. Correlation was determined by Pearson’s correlation coefficient between 15 m fat mass change (kg) vs baseline and 15 m leptin (ng/mL) change vs baseline (H).

Article Snippet: Testosterone, estrogen, follicle-stimulating hormone (FSH), luteinizing hormone (LH), C-terminal telopeptide of type I collagen (CTX), osteocalcin, total 25OHD, and hair cortisol were assayed on a Roche cobas e411 automated clinical platform; Inhibin B, PTH and adiponectin (ALPCO total adiponectin cat# 80-ADPHU-E01) were assayed via ELISA; Leptin was assayed via RIA (Millipore cat# HL-81K), all by the ONPRC Endocrine Technologies Core.

Techniques: