Review



add  (ATCC)


Bioz Verified Symbol ATCC is a verified supplier
Bioz Manufacturer Symbol ATCC manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    ATCC add
    The cumulative fractional inhibitory concentration index (∑FICI) range of compounds 6 , 11 , 12 , and 13 in combination with antibiotics against MRSA ATCC 33592. ∑FICI was interpreted as follows: ∑FICI of ≤0.5 is considered to demonstrate synergy <t> (SYN). </t> An ∑FICI of >0.5–1.25 was categorized as additive <t> (ADD). </t> ∑FICI of >1.25–4 was considered as indifference (IND), while ∑FICI values of >4 were categorized as antagonistic
    Add, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/add/product/ATCC
    Average 90 stars, based on 1 article reviews
    add - by Bioz Stars, 2026-02
    90/100 stars

    Images

    1) Product Images from "Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria † †Electronic supplementary information (ESI) available: Synthesis and characterization data of compounds ( 1 H, 13 C NMR and HRMS). Bacterial strains, media, cell lines and reagents used. Protocols for the determination of the MICs and MBCs against bacteria, synergy of compounds with standard antibiotics, in vitro cytotoxicity analysis of compounds 6 , 11 , 12 and 13 against human colorectal and murine macrophage cells, hemolysis assay, time-kill kinetics analysis, intracellular infection of J774 cells with MRSA and treatment with compounds 6 and 12 . Table of bacterial isolates used in this study. See DOI: 10.1039/c9md00391f "

    Article Title: Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria † †Electronic supplementary information (ESI) available: Synthesis and characterization data of compounds ( 1 H, 13 C NMR and HRMS). Bacterial strains, media, cell lines and reagents used. Protocols for the determination of the MICs and MBCs against bacteria, synergy of compounds with standard antibiotics, in vitro cytotoxicity analysis of compounds 6 , 11 , 12 and 13 against human colorectal and murine macrophage cells, hemolysis assay, time-kill kinetics analysis, intracellular infection of J774 cells with MRSA and treatment with compounds 6 and 12 . Table of bacterial isolates used in this study. See DOI: 10.1039/c9md00391f

    Journal: RSC Medicinal Chemistry

    doi: 10.1039/c9md00391f

    The cumulative fractional inhibitory concentration index (∑FICI) range of compounds 6 , 11 , 12 , and 13 in combination with antibiotics against MRSA ATCC 33592. ∑FICI was interpreted as follows: ∑FICI of ≤0.5 is considered to demonstrate synergy (SYN). An ∑FICI of >0.5–1.25 was categorized as additive (ADD). ∑FICI of >1.25–4 was considered as indifference (IND), while ∑FICI values of >4 were categorized as antagonistic
    Figure Legend Snippet: The cumulative fractional inhibitory concentration index (∑FICI) range of compounds 6 , 11 , 12 , and 13 in combination with antibiotics against MRSA ATCC 33592. ∑FICI was interpreted as follows: ∑FICI of ≤0.5 is considered to demonstrate synergy (SYN). An ∑FICI of >0.5–1.25 was categorized as additive (ADD). ∑FICI of >1.25–4 was considered as indifference (IND), while ∑FICI values of >4 were categorized as antagonistic

    Techniques Used: Concentration Assay



    Similar Products

    add  (ATCC)
    90
    ATCC add
    The cumulative fractional inhibitory concentration index (∑FICI) range of compounds 6 , 11 , 12 , and 13 in combination with antibiotics against MRSA ATCC 33592. ∑FICI was interpreted as follows: ∑FICI of ≤0.5 is considered to demonstrate synergy <t> (SYN). </t> An ∑FICI of >0.5–1.25 was categorized as additive <t> (ADD). </t> ∑FICI of >1.25–4 was considered as indifference (IND), while ∑FICI values of >4 were categorized as antagonistic
    Add, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/add/product/ATCC
    Average 90 stars, based on 1 article reviews
    add - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    The cumulative fractional inhibitory concentration index (∑FICI) range of compounds 6 , 11 , 12 , and 13 in combination with antibiotics against MRSA ATCC 33592. ∑FICI was interpreted as follows: ∑FICI of ≤0.5 is considered to demonstrate synergy (SYN). An ∑FICI of >0.5–1.25 was categorized as additive (ADD). ∑FICI of >1.25–4 was considered as indifference (IND), while ∑FICI values of >4 were categorized as antagonistic

    Journal: RSC Medicinal Chemistry

    Article Title: Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria † †Electronic supplementary information (ESI) available: Synthesis and characterization data of compounds ( 1 H, 13 C NMR and HRMS). Bacterial strains, media, cell lines and reagents used. Protocols for the determination of the MICs and MBCs against bacteria, synergy of compounds with standard antibiotics, in vitro cytotoxicity analysis of compounds 6 , 11 , 12 and 13 against human colorectal and murine macrophage cells, hemolysis assay, time-kill kinetics analysis, intracellular infection of J774 cells with MRSA and treatment with compounds 6 and 12 . Table of bacterial isolates used in this study. See DOI: 10.1039/c9md00391f

    doi: 10.1039/c9md00391f

    Figure Lengend Snippet: The cumulative fractional inhibitory concentration index (∑FICI) range of compounds 6 , 11 , 12 , and 13 in combination with antibiotics against MRSA ATCC 33592. ∑FICI was interpreted as follows: ∑FICI of ≤0.5 is considered to demonstrate synergy (SYN). An ∑FICI of >0.5–1.25 was categorized as additive (ADD). ∑FICI of >1.25–4 was considered as indifference (IND), while ∑FICI values of >4 were categorized as antagonistic

    Article Snippet: Compounds 6 , 12 , and 13 demonstrated additivity with daptomycin but these same compounds did not synergize with either linezolid or vancomycin ( ). table ft1 table-wrap mode="anchored" t5 caption a7 Entry Antibiotic MIC alone Combination MIC ∑FICI SYN/ADD/IND Combination MIC ∑FICI SYN/ADD/IND Combination MIC ∑FICI SYN/ADD/IND Combination MIC ∑FICI SYN/ADD/IND Antibiotic Antibiotic 6 Antibiotic 11 Antibiotic 12 Antibiotic 13 1 Linezolid 2 2 0.0625 1.03 ADD 2 0.25 1.25 ADD 2 0.0625 1.06 ADD 2 0.5 1.50 IND 2 Methicillin 128 4 1 0.53 SYN 16 0.5 0.63 ADD 32 0.25 0.50 SYN 32 0.25 0.50 SYN 3 Daptomycin 0.50 0.25 0.25 0.63 ADD 0.125 0.25 0.50 SYN 0.25 0.125 0.63 ADD 0.25 0.25 0.75 ADD 4 Vancomycin 1 1 0.0625 1.03 ADD 1 0.0625 1.06 ADD 0.5 0.5 1.00 ADD 0.5 0.5 1.00 ADD Open in a separate window caption a8 The cumulative fractional inhibitory concentration index (∑FICI) range of compounds 6 , 11 , 12 , and 13 in combination with antibiotics against MRSA ATCC 33592.

    Techniques: Concentration Assay