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5 iodowillardiine  (Tocris)


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    Structured Review

    Tocris 5 iodowillardiine
    5 Iodowillardiine, supplied by Tocris, used in various techniques. Bioz Stars score: 91/100, based on 11 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/0307/(S)-(-)-5-Iodowillardiine/pmc13109363-366-8-10
    Average 91 stars, based on 11 article reviews
    5 iodowillardiine - by Bioz Stars, 2026-09
    91/100 stars

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    Related Articles

    other:


    Article Title: Structures of partially occupied hetero-tetramers provide insight into kainate receptor activation and desensitization
    Article Snippet: 0.4 μL of 2 mM 5-iodowillardiine (Tocris) was added to the protein in grid, mixed quickly, and immediately blotted (2 s blot time, −2 or −4 blot force) and plunge-frozen in liquid ethane using a Vitrobot Mk IV (Thermo Fisher).

    Article Title: Tethered ligands reveal glutamate receptor desensitization depends on subunit occupancy
    Article Snippet: L-Glutamate (Glu) was obtained from Sigma (49449, >99.5%), ( S )-5-Iodowillardiine (5-IW) from Tocris (0307, >98%).

    Article Title: Structures of partially occupied hetero-tetramers provide insight into kainate receptor activation and desensitization
    Article Snippet: The agonists L‐glutamate (Glu, Sigma 49449), ( S )−5-iodowillardiine (5‐IW, Tocris 0307) and ( S )-AMPA (AMPA, Alomone Labs A-267) and the antagonist kynurenic acid (Kyn, Alomone Labs K-110) were applied in extracellular solution.

    Article Title: Tethered ligands reveal glutamate receptor desensitization depends on subunit occupancy
    Article Snippet: L-Glutamate (Glu) was obtained from Sigma (49449, >99.5%), (S)-5iodowillardiine55 (5-IW) from Tocris (0307, >98%).

    Article Title: Structures of partially occupied hetero-tetramers provide insight into kainate receptor activation and desensitization.
    Article Snippet: The agonists L‐glutamate (Glu, Sigma 49449), (S)−5-iodowillardiine (5‐IW, Tocris 0307) and (S)-AMPA (AMPA, Alomone Labs A-267) and the antagonist kynurenic acid (Kyn, Alomone Labs K-110) were applied in extracellular solution.

    Article Title: Kainate Receptor Activation Shapes Short-Term Synaptic Plasticity by Controlling Receptor Lateral Mobility at Glutamatergic Synapses
    Article Snippet: The maximal Concanavalin-A effect was typically achieved within 8 min after perfusion. ( S )-5-Iodowillardiine (5-IW) was purchased from Tocris Bioscience (Italy).

    Synthesized:

    Article Title: A pharmacological profile of the high-affinity GluK5 kainate receptor.
    Article Snippet: Mouse GluK5 was expressed in Sf9 insect cells and radiolabelled with [H]-kainate in receptor binding assays (Kd1⁄46.9 nM).. Western immunoblotting indicated an Sf9 GluK5 band doublet corresponding to the glycosylated (128 kDa) and deglycosylated (111 kDa) protein, which was identical to the band pattern of native rat brain GluK5.. A pharmacological profile of the high-affinity kainate receptor GluK5 is described which is distinct from the profiles of other kainate receptors (GluK1-3).



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