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spatial transcriptome analysis platform sdas  (Complete Genomics Inc)


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    Complete Genomics Inc spatial transcriptome analysis platform sdas
    Spatial Transcriptome Analysis Platform Sdas, supplied by Complete Genomics Inc, used in various techniques. Bioz Stars score: 99/100, based on 485 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/spatial+transcriptome+analysis/Stereo-seq+Transcriptomics+Set+for+FFPE/pm41527855-113-26-34
    Average 99 stars, based on 485 article reviews
    spatial transcriptome analysis platform sdas - by Bioz Stars, 2026-11
    99/100 stars

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    Spatial Transcriptomics:

    Article Title: A pan cancer multi omics analysis of OLR1 reveals its association with tumor immunity metabolic pathways and clinical prognosis
    Article Snippet: .. Spatial transcriptomics datasets were obtained from the STOmics database (https://db.cngb.org/stomics/) and the GEO database (https://www.ncbi.nlm.nih.gov/geo/), including STDS0000027, STDS0000033, STDS0000046, GSM5924031, and GSM6505133. ..

    Article Title: Spi1-Soat1 Transcriptional axis drives microglial lipid droplet accumulation and secondary brain injury after intracerebral hemorrhage
    Article Snippet: .. Cholesterol metabolic pathway activation and microglia-specific upregulation of Soat1 are tightly associated with lipid droplet accumulation after ICH To define the core metabolic pathways and key regulators driving microglial LD accumulation after ICH, we analyzed the day 7 perihematomal tissue subset of a spatial transcriptomics dataset (STOmics DB, ID:STT0000047), with a focus on lipid metabolic cascades underlying LD biogenesis (Fig. 3A). ..

    Analysis:

    Article Title: Diverse infections transcriptionally reprogram the intestinal epithelium and epithelial-immune cell interactions.
    Article Snippet: .. Indeed, using Stereo-seq (STOmics) spatial transcriptomic analysis, which profiles host and microbial RNA, we found that Yersinia transcripts were localized to the basal region of the PG and did not extend to the enterocytes overlaying the PG (Supplementary Fig. 10g). ..

    Sequencing:

    Article Title: Multi-omics integration and machine learning identify an ACKR1 + endothelial cell-based lactate-immune signature associated with carotid plaque vulnerability and progression.
    Article Snippet: .. The internal singlecell and spatial transcriptomes were deposited with our previous study (Lai et al., Nat Cardiovasc Res, 2025) in the Genome Sequence Archive for Human at the National Genomics Data Center under accession HRA006030 (https://ngdc.cncb.ac.cn/gsa-human), with backups in the China National GeneBank: spatial transcriptomes in the STOmics Database (STT0000052, https://db.cngb.org/stomics/) and single-cell data in the China National Sequence Archive (CNP0004894, https:// db.cngb.org/cnsa/). ..

    Single Cell:

    Article Title: Multi-omics integration and machine learning identify an ACKR1 + endothelial cell-based lactate-immune signature associated with carotid plaque vulnerability and progression.
    Article Snippet: .. The internal singlecell and spatial transcriptomes were deposited with our previous study (Lai et al., Nat Cardiovasc Res, 2025) in the Genome Sequence Archive for Human at the National Genomics Data Center under accession HRA006030 (https://ngdc.cncb.ac.cn/gsa-human), with backups in the China National GeneBank: spatial transcriptomes in the STOmics Database (STT0000052, https://db.cngb.org/stomics/) and single-cell data in the China National Sequence Archive (CNP0004894, https:// db.cngb.org/cnsa/). ..

    Activation Assay:

    Article Title: Spi1-Soat1 Transcriptional axis drives microglial lipid droplet accumulation and secondary brain injury after intracerebral hemorrhage
    Article Snippet: .. Cholesterol metabolic pathway activation and microglia-specific upregulation of Soat1 are tightly associated with lipid droplet accumulation after ICH To define the core metabolic pathways and key regulators driving microglial LD accumulation after ICH, we analyzed the day 7 perihematomal tissue subset of a spatial transcriptomics dataset (STOmics DB, ID:STT0000047), with a focus on lipid metabolic cascades underlying LD biogenesis (Fig. 3A). ..

    Tissue:

    Article Title: Spi1-Soat1 Transcriptional axis drives microglial lipid droplet accumulation and secondary brain injury after intracerebral hemorrhage
    Article Snippet: .. Cholesterol metabolic pathway activation and microglia-specific upregulation of Soat1 are tightly associated with lipid droplet accumulation after ICH To define the core metabolic pathways and key regulators driving microglial LD accumulation after ICH, we analyzed the day 7 perihematomal tissue subset of a spatial transcriptomics dataset (STOmics DB, ID:STT0000047), with a focus on lipid metabolic cascades underlying LD biogenesis (Fig. 3A). ..

    H&E Stain:

    Article Title: Spatial transcriptomic profiling of porcine tissue microarray detecting subclinical circovirus infection
    Article Snippet: .. The first section was subjected to H&E staining for histological evaluation, while the second was mounted directly onto a Stereo-seq chip N Slide V1.0 (STOmics, Cat. No. 210CN114). .. Subsequent processing was performed according to the Stereo-seq Transcriptomics Set for FFPE User Manual (Document No. STUM-TT004) using the Stereo-seq Transcriptomics N Kit V1.0 (Cat. No. 211KN114) and Stereo-seq 16 Barcode Library Preparation Kit V1.0 (Cat. No. 111KL160).



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    a Schematic diagram of the spatial <t>transcriptome</t> analysis using Xenium Prime 5K. Formalin fixed paraffin embedded (FFPE) sections were prepared from 12-month-old Tau Tg mice and age-matched WT controls. b UMAP visualizing the cell cluster detected by Xenium in the brains of Tau Tg and WT mice. Neuronal cells were classified as IT (intratelencephalic), ET (extratelencephalic), Glut (glutamatergic), NP (near-projecting), CT (corticothalamic), L6b (layer 6b), DG (dentate gyrus), IMN (immature neurons), CTX (cerebral cortex), CGE (caudal ganglionic eminence), GABA (GABAergic), MGE (medial ganglionic eminence), CNU (cerebral nuclei), LGE (lateral ganglionic eminence), Hya (anterior hypothalamic), HY (hypothalamus), MM (medial mammillary nucleus), LH (lateral habenula), TH (thalamus), MB (midbrain), HB (hindbrain), Sero (serotonergic), MY (medulla), NN (non-neuronal), NP (near-projecting), OB (olfactory bulb), OEC (olfactory ensheathing cells), and OLF (olfactory areas). c Cxcl10 mRNA signal was plotted using Feature Plot on UMAP. d Quantitative Cxcl10 gene expression using violin plots in AC-Epen, BAM, DG-IMN Glut, IT-ET Glut, MG, and T cell types. e, h Representative plots of the result of re-clustering AC-Epen ( e ) and immune cluster ( h ), respectively. f Plots of Cxcl10 + cells in the cluster shown in and represented according to genotype. g, j Figures showing spatial distribution of AC8 ( g ) and MG3 ( j ) clusters in the brains of WT and Tau Tg mice. k Representative images of coronal section of mouse brain by Xenium explorer. Scale bar = 1 mm. l Spatial information of Cxcl10 + astrocytes and microglia in the hippocampus of Tau Tg mice using Xenium explorer. Scale bar = 100 μm. Number of mice used: male WT (n = 1), male Tau Tg (n = 1), female WT (n = 1), and female Tau Tg (n = 1). Statistical analysis was performed using a Wilcoxon rank sum U statistic test ( d ). Source data are provided in the Source Data file.
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    a Schematic diagram of the spatial <t>transcriptome</t> analysis using Xenium Prime 5K. Formalin fixed paraffin embedded (FFPE) sections were prepared from 12-month-old Tau Tg mice and age-matched WT controls. b UMAP visualizing the cell cluster detected by Xenium in the brains of Tau Tg and WT mice. Neuronal cells were classified as IT (intratelencephalic), ET (extratelencephalic), Glut (glutamatergic), NP (near-projecting), CT (corticothalamic), L6b (layer 6b), DG (dentate gyrus), IMN (immature neurons), CTX (cerebral cortex), CGE (caudal ganglionic eminence), GABA (GABAergic), MGE (medial ganglionic eminence), CNU (cerebral nuclei), LGE (lateral ganglionic eminence), Hya (anterior hypothalamic), HY (hypothalamus), MM (medial mammillary nucleus), LH (lateral habenula), TH (thalamus), MB (midbrain), HB (hindbrain), Sero (serotonergic), MY (medulla), NN (non-neuronal), NP (near-projecting), OB (olfactory bulb), OEC (olfactory ensheathing cells), and OLF (olfactory areas). c Cxcl10 mRNA signal was plotted using Feature Plot on UMAP. d Quantitative Cxcl10 gene expression using violin plots in AC-Epen, BAM, DG-IMN Glut, IT-ET Glut, MG, and T cell types. e, h Representative plots of the result of re-clustering AC-Epen ( e ) and immune cluster ( h ), respectively. f Plots of Cxcl10 + cells in the cluster shown in and represented according to genotype. g, j Figures showing spatial distribution of AC8 ( g ) and MG3 ( j ) clusters in the brains of WT and Tau Tg mice. k Representative images of coronal section of mouse brain by Xenium explorer. Scale bar = 1 mm. l Spatial information of Cxcl10 + astrocytes and microglia in the hippocampus of Tau Tg mice using Xenium explorer. Scale bar = 100 μm. Number of mice used: male WT (n = 1), male Tau Tg (n = 1), female WT (n = 1), and female Tau Tg (n = 1). Statistical analysis was performed using a Wilcoxon rank sum U statistic test ( d ). Source data are provided in the Source Data file.
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    Image Search Results


    a Schematic diagram of the spatial transcriptome analysis using Xenium Prime 5K. Formalin fixed paraffin embedded (FFPE) sections were prepared from 12-month-old Tau Tg mice and age-matched WT controls. b UMAP visualizing the cell cluster detected by Xenium in the brains of Tau Tg and WT mice. Neuronal cells were classified as IT (intratelencephalic), ET (extratelencephalic), Glut (glutamatergic), NP (near-projecting), CT (corticothalamic), L6b (layer 6b), DG (dentate gyrus), IMN (immature neurons), CTX (cerebral cortex), CGE (caudal ganglionic eminence), GABA (GABAergic), MGE (medial ganglionic eminence), CNU (cerebral nuclei), LGE (lateral ganglionic eminence), Hya (anterior hypothalamic), HY (hypothalamus), MM (medial mammillary nucleus), LH (lateral habenula), TH (thalamus), MB (midbrain), HB (hindbrain), Sero (serotonergic), MY (medulla), NN (non-neuronal), NP (near-projecting), OB (olfactory bulb), OEC (olfactory ensheathing cells), and OLF (olfactory areas). c Cxcl10 mRNA signal was plotted using Feature Plot on UMAP. d Quantitative Cxcl10 gene expression using violin plots in AC-Epen, BAM, DG-IMN Glut, IT-ET Glut, MG, and T cell types. e, h Representative plots of the result of re-clustering AC-Epen ( e ) and immune cluster ( h ), respectively. f Plots of Cxcl10 + cells in the cluster shown in and represented according to genotype. g, j Figures showing spatial distribution of AC8 ( g ) and MG3 ( j ) clusters in the brains of WT and Tau Tg mice. k Representative images of coronal section of mouse brain by Xenium explorer. Scale bar = 1 mm. l Spatial information of Cxcl10 + astrocytes and microglia in the hippocampus of Tau Tg mice using Xenium explorer. Scale bar = 100 μm. Number of mice used: male WT (n = 1), male Tau Tg (n = 1), female WT (n = 1), and female Tau Tg (n = 1). Statistical analysis was performed using a Wilcoxon rank sum U statistic test ( d ). Source data are provided in the Source Data file.

    Journal: bioRxiv

    Article Title: CXCL10 drives female-specific tau pathology progression and defines sex-dependent vulnerability in tauopathy model mice

    doi: 10.64898/2026.04.19.719088

    Figure Lengend Snippet: a Schematic diagram of the spatial transcriptome analysis using Xenium Prime 5K. Formalin fixed paraffin embedded (FFPE) sections were prepared from 12-month-old Tau Tg mice and age-matched WT controls. b UMAP visualizing the cell cluster detected by Xenium in the brains of Tau Tg and WT mice. Neuronal cells were classified as IT (intratelencephalic), ET (extratelencephalic), Glut (glutamatergic), NP (near-projecting), CT (corticothalamic), L6b (layer 6b), DG (dentate gyrus), IMN (immature neurons), CTX (cerebral cortex), CGE (caudal ganglionic eminence), GABA (GABAergic), MGE (medial ganglionic eminence), CNU (cerebral nuclei), LGE (lateral ganglionic eminence), Hya (anterior hypothalamic), HY (hypothalamus), MM (medial mammillary nucleus), LH (lateral habenula), TH (thalamus), MB (midbrain), HB (hindbrain), Sero (serotonergic), MY (medulla), NN (non-neuronal), NP (near-projecting), OB (olfactory bulb), OEC (olfactory ensheathing cells), and OLF (olfactory areas). c Cxcl10 mRNA signal was plotted using Feature Plot on UMAP. d Quantitative Cxcl10 gene expression using violin plots in AC-Epen, BAM, DG-IMN Glut, IT-ET Glut, MG, and T cell types. e, h Representative plots of the result of re-clustering AC-Epen ( e ) and immune cluster ( h ), respectively. f Plots of Cxcl10 + cells in the cluster shown in and represented according to genotype. g, j Figures showing spatial distribution of AC8 ( g ) and MG3 ( j ) clusters in the brains of WT and Tau Tg mice. k Representative images of coronal section of mouse brain by Xenium explorer. Scale bar = 1 mm. l Spatial information of Cxcl10 + astrocytes and microglia in the hippocampus of Tau Tg mice using Xenium explorer. Scale bar = 100 μm. Number of mice used: male WT (n = 1), male Tau Tg (n = 1), female WT (n = 1), and female Tau Tg (n = 1). Statistical analysis was performed using a Wilcoxon rank sum U statistic test ( d ). Source data are provided in the Source Data file.

    Article Snippet: FFPE brain sections were analyzed using Xenium spatial transcriptome analysis (10x Genomics).

    Techniques: Formalin-fixed Paraffin-Embedded, Olfactory, Gene Expression