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semiconductor-based oligonucleotide microarray  (CombiMatrix)

 
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    CombiMatrix semiconductor-based oligonucleotide microarray
    Semiconductor Based Oligonucleotide Microarray, supplied by CombiMatrix, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/semiconductor-based+microarray/semiconductor+based+microarray/pm20797431-47-5-15
    Average 90 stars, based on 1 article reviews
    semiconductor-based oligonucleotide microarray - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Microarray:

    Article Title: Development of the Large-Scale Oligonucleotide Chip for the Diagnosis of Plant Viruses and its Practical Use
    Article Snippet: .. Tiberini et al. (2010) developed the fluorescent based microarray system by Combimatrix to detect and identify 10 tomato viruses, which are economically important. ..

    Article Title: Oligonucleotide microarray-based detection and identification of 10 major tomato viruses.
    Article Snippet: A DNA microarray chip was developed for screening 10 major economically important tomato viruses from infected plants using “Combimatrix” platform 40-mer oligonucleotide probes.. A total of 279 oligonucleotide virus probes were specific for simultaneous multiple detection, identification, differentiation and/or genotyping of each of the following tomato RNA viruses and/or strains and a virus satellite: Cucumber mosaic virus, Cucumber mosaic virus satellite RNA, Tomato infectious chlorosis virus, Tomato chlorosis virus, Tomato spotted wilt virus, Pepino mosaic virus, Potato virus Y, Tobacco mosaic virus and Tomato mosaic virus.. This selection included both positive and negative single-stranded RNA viruses.

    Article Title: Integrated biosensor and stimulation system for diagnosis and therapy
    Article Snippet: .. Customizable microarray platform, e.g., CombiMatrix, including semiconductor-based desktop microarray platform may fabricate custom oligonucleotide biochips. .. Another example of probe arranger 420 is photolithography, e.g., Affymetrix GeneChips.

    other:

    Article Title: An integrated bioinformatics approach to the characterization of influenza A/H5N1 viral sequences by microarray data: Implication for monitoring H5N1 emerging strains and designing appropriate influenza vaccines.
    Article Snippet: In order to characterize A/H5N1 viral sequences, a bioinformatics approach accurately identified viral sequences from discovery of a sequence signature, which provided enough distinctive information for sequence identification.. Eight highly pathogenic H5N1 viral isolations were collected from different areas of Thailand between 2003 and 2006, and were used for analysis of H5N1 genotypic testing with a semiconductor-based oligonucleotide microarray.. All H5N1 samples and H1N1, H4N8 negative controls were correctly subtyped.

    Article Title: Integrated biosensor and simulation system for diagnosis and therapy
    Article Snippet: Another example of integrated sensor detection system 231 assay, can be GeneFluidics 3D micro-fabricated platform with embedded electrochemical sensor array.

    Article Title: Use of consensus sequences for the design of high density resequencing microarrays: the influenza virus paradigm
    Article Snippet: Recently, Combimatrix Corporation (Mukilteo, WA) developed a semiconductor-based microarray and an integrated microfluidic array enabling the detection of 15 HA and 9 NA [ , ].

    Article Title: Integrated biosensor and simulation systems for diagnosis and therapy
    Article Snippet: Another example of integrated sensor detection system 231 assay, can be GeneFluidics 3D micro-fabricated platform with embedded electrochemical sensor array.



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    Image Search Results


    Simplified schematic overview of the gold nanoparticle (NP)-based microarray assay . The target is whole viral genome RNA (blue line), end modified capture oligos are 40 bp in length (black line) printed on the amino-modified glass slide and intermediate oligos are 65 bp in length (purple line) including 25-mer poly (A) tail (red line). The probe is 15 nm gold nanoparticles (NP) functionalized with poly dT tail (green line). The specific hybridizations between the capture oligo, RNA (or DNA) and intermediate oligo take place to form sandwich complexes in Step 1, then the gold NP probes bind to the complexes in Step 2, and silver staining is in Step 3.

    Journal: BMC Biotechnology

    Article Title: Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assay

    doi: 10.1186/1472-6750-10-74

    Figure Lengend Snippet: Simplified schematic overview of the gold nanoparticle (NP)-based microarray assay . The target is whole viral genome RNA (blue line), end modified capture oligos are 40 bp in length (black line) printed on the amino-modified glass slide and intermediate oligos are 65 bp in length (purple line) including 25-mer poly (A) tail (red line). The probe is 15 nm gold nanoparticles (NP) functionalized with poly dT tail (green line). The specific hybridizations between the capture oligo, RNA (or DNA) and intermediate oligo take place to form sandwich complexes in Step 1, then the gold NP probes bind to the complexes in Step 2, and silver staining is in Step 3.

    Article Snippet: CombiMatrix Corporation has also developed a semiconductor-based Influenza A Research Microarray that can detect all known subtypes of influenza A viruses within 5 hours [ ].

    Techniques: Microarray, Modification, Silver Staining

    Image from a Verigene ID™ detection system . (A). Microarray layout with positive control capture (closed red circles on the top), negative control which uses printing buffer as capture (closed yellow circles), M, H5, and N1 gene captures (filled as variable color of closed circles, spotted in triplicate) are indicated. (B). The light shades represent strong silver staining signals. A portion of the microarray images for DNA oligonucleotide following hybridization with PCR fragment are shown and light shades represent greater silver intensities for the M and H5 genes. The spots at the top of each array are positive controls. (C). Silver staining image for individual or multiple PCR products are shown and labeled. (D). Typical genomic microarray silver staining image from 0.2 μg of H1N1, H3N2 or H5N1 viral RNA are shown. The boxed areas highlight hits for specific subtypes.

    Journal: BMC Biotechnology

    Article Title: Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assay

    doi: 10.1186/1472-6750-10-74

    Figure Lengend Snippet: Image from a Verigene ID™ detection system . (A). Microarray layout with positive control capture (closed red circles on the top), negative control which uses printing buffer as capture (closed yellow circles), M, H5, and N1 gene captures (filled as variable color of closed circles, spotted in triplicate) are indicated. (B). The light shades represent strong silver staining signals. A portion of the microarray images for DNA oligonucleotide following hybridization with PCR fragment are shown and light shades represent greater silver intensities for the M and H5 genes. The spots at the top of each array are positive controls. (C). Silver staining image for individual or multiple PCR products are shown and labeled. (D). Typical genomic microarray silver staining image from 0.2 μg of H1N1, H3N2 or H5N1 viral RNA are shown. The boxed areas highlight hits for specific subtypes.

    Article Snippet: CombiMatrix Corporation has also developed a semiconductor-based Influenza A Research Microarray that can detect all known subtypes of influenza A viruses within 5 hours [ ].

    Techniques: Microarray, Positive Control, Negative Control, Silver Staining, Hybridization, Labeling

    Results of genomic array detection of influenza A viruses with specific captures

    Journal: BMC Biotechnology

    Article Title: Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assay

    doi: 10.1186/1472-6750-10-74

    Figure Lengend Snippet: Results of genomic array detection of influenza A viruses with specific captures

    Article Snippet: CombiMatrix Corporation has also developed a semiconductor-based Influenza A Research Microarray that can detect all known subtypes of influenza A viruses within 5 hours [ ].

    Techniques:

    Resequencing microarray output for identification and characterisation of the 12 influenza A viral RNAs

    Journal: BMC Genomics

    Article Title: Use of consensus sequences for the design of high density resequencing microarrays: the influenza virus paradigm

    doi: 10.1186/1471-2164-11-586

    Figure Lengend Snippet: Resequencing microarray output for identification and characterisation of the 12 influenza A viral RNAs

    Article Snippet: Recently, Combimatrix Corporation (Mukilteo, WA) developed a semiconductor-based microarray and an integrated microfluidic array enabling the detection of 15 HA and 9 NA [ , ].

    Techniques: Microarray

    Avian sequences reconstructed by the PathogenID v2.0 and BLASTN alignment

    Journal: BMC Genomics

    Article Title: Use of consensus sequences for the design of high density resequencing microarrays: the influenza virus paradigm

    doi: 10.1186/1471-2164-11-586

    Figure Lengend Snippet: Avian sequences reconstructed by the PathogenID v2.0 and BLASTN alignment

    Article Snippet: Recently, Combimatrix Corporation (Mukilteo, WA) developed a semiconductor-based microarray and an integrated microfluidic array enabling the detection of 15 HA and 9 NA [ , ].

    Techniques: Sequencing, Microarray