Review



plpro fluorogenic substrate  (BPS Bioscience)


Bioz Verified Symbol BPS Bioscience is a verified supplier
Bioz Manufacturer Symbol BPS Bioscience manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 93

    Structured Review

    BPS Bioscience plpro fluorogenic substrate
    Plpro Fluorogenic Substrate, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 93/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plpro+fluorogenic+substrate/PLPro+Substrate/pm38008194-42-1-5
    Average 93 stars, based on 8 article reviews
    plpro fluorogenic substrate - by Bioz Stars, 2026-10
    93/100 stars

    Images

    Related Articles

    Concentration Assay:

    Article Title: Dual inhibition of coronavirus M pro and PL pro enzymes by phenothiazines and their antiviral activity
    Article Snippet: .. The PL pro fluorogenic substrate (BPS Biosciences, 79997) was provided at a concentration of 5 mM (4.2 mg/mL) in DMSO which was further diluted to give a stock solution of 2 mg/mL in DMSO. .. To assess enzymatic activity, N -2-hydroxyethylpiperazine- N -2-ethane sulfonic acid (HEPES) buffer (395.6 μL; 25 mM; pH 7.0) was mixed with 0.4 μL of M pro stock solution or 0.4 μL of PL pro stock solution and 2 μL of their appropriate fluorogenic substrate stock solution in a quartz cuvette of 1 cm path length and measured using a Varian Cary Eclipse Fluorescence spectrophotometer (Varian Inc., Palo Alto CA, USA).

    Article Title: A phenothiazine urea derivative broadly inhibits coronavirus replication via viral protease inhibition.
    Article Snippet: Coronavirus (CoV) replication requires efficient cleavage of viral polyproteins into an array of non-structural proteins involved in viral replication, organelle formation, viral RNA synthesis, and host shutoff.. Human CoVs (HCoVs) encode two viral cysteine proteases, main protease (Mpro) and papain-like protease (PLpro), that mediate polyprotein cleavage.. Using a structure-guided approach, a phenothiazine urea derivative that inhibits both SARS-CoV-2 Mpro and PLpro protease activity was identified.

    Ubiquitin Proteomics:

    Article Title: Integrated machine learning and structure-based discovery of noncovalent natural product inhibitors targeting SARS-CoV-2 papain-like protease
    Article Snippet: Enzymatic inhibition of SARS-CoV-2 PLpro was assessed using a fluorescence-based assay kit (BPS Bioscience, catalog number 79995-1) (Carmo et al., 2024). .. The fluorogenic peptide substrate used in the assay was Z-Arg-Leu-Arg-Gly-Gly-7-amido-4-methylcoumarin (Z-RLRGGAMC; BPS Bioscience, catalog number 79997), a ubiquitin-derived 5-mer peptide that releases AMC upon proteolytic cleavage (Hersi et al., 2023). ..

    other:

    Article Title: Effect of new derivatives of 6,7-dimethoxyquinazoline-4(3H)-one with amino acid residues and dipeptide fragments on the activity of the main protease (Mpro) and papain-like protease (PLpro) of SARS-CoV-2
    Article Snippet: Полученную смесь инкубировали 10 мин при температуре 37 °С, после чего в анализируемую среду вносили хромогенный субстрат PLpro ubiquitinated substrate (BPS Bioscience, Inc., США) в конечной концентрации 20 мкМ и доводили до 200 мкл буферным раствором 20 мМ HEPES рН 6.0 + + 0.4 мМ этилендиаминтетрауксусной кислоты (ЭДТА) + 1 мМ дитиотреитол + 1% глицерин.



    Similar Products

    93
    BPS Bioscience fluorogenic peptide substrate
    Fluorogenic Peptide Substrate, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plpro+fluorogenic+substrate/PLPro+Substrate/10__25259_slash_jksus_15_2026-178-1-11
    Average 93 stars, based on 1 article reviews
    fluorogenic peptide substrate - by Bioz Stars, 2026-10
    93/100 stars
      Buy from Supplier

    93
    BPS Bioscience plpro fluorogenic substrate
    Plpro Fluorogenic Substrate, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plpro+fluorogenic+substrate/PLPro+Substrate/pm38008194-42-1-5
    Average 93 stars, based on 1 article reviews
    plpro fluorogenic substrate - by Bioz Stars, 2026-10
    93/100 stars
      Buy from Supplier

    93
    BPS Bioscience pro fluorogenic substrate
    Pro Fluorogenic Substrate, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plpro+fluorogenic+substrate/PLPro+Substrate/bio_rxiv__2023__09__11__557219-31-2-5
    Average 93 stars, based on 1 article reviews
    pro fluorogenic substrate - by Bioz Stars, 2026-10
    93/100 stars
      Buy from Supplier

    Image Search Results