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platform-based microarray analysis  (Thermo Fisher)


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    Structured Review

    Thermo Fisher platform-based microarray analysis
    A. Statistical Analysis of <t>Microarray</t> (SAM) plot, at a 0.109 false discovery rate (FDR). B. Gene ontology (GO) analysis; selected GO categories shown. C. Venn diagram comparing differentially expressed genes in eyes of RA-treated embryos with those of RA-treated whole embryos during somitogenesis and with those of hearts of RA-treated larvae.
    Platform Based Microarray Analysis, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/platform-based+microarray+analysis/pmc04546582-389-10-8
    Average 90 stars, based on 1 article reviews
    platform-based microarray analysis - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "Retinoic Acid Signaling Regulates Differential Expression of the Tandemly-Duplicated Long Wavelength-Sensitive Cone Opsin Genes in Zebrafish"

    Article Title: Retinoic Acid Signaling Regulates Differential Expression of the Tandemly-Duplicated Long Wavelength-Sensitive Cone Opsin Genes in Zebrafish

    Journal: PLoS Genetics

    doi: 10.1371/journal.pgen.1005483

    A. Statistical Analysis of Microarray (SAM) plot, at a 0.109 false discovery rate (FDR). B. Gene ontology (GO) analysis; selected GO categories shown. C. Venn diagram comparing differentially expressed genes in eyes of RA-treated embryos with those of RA-treated whole embryos during somitogenesis and with those of hearts of RA-treated larvae.
    Figure Legend Snippet: A. Statistical Analysis of Microarray (SAM) plot, at a 0.109 false discovery rate (FDR). B. Gene ontology (GO) analysis; selected GO categories shown. C. Venn diagram comparing differentially expressed genes in eyes of RA-treated embryos with those of RA-treated whole embryos during somitogenesis and with those of hearts of RA-treated larvae.

    Techniques Used: Microarray

    A. cyp26b1 . B. hoxb6a . C. socs3a . D. dkk1b . E. sfrp1a . F. wnt 11 . G. and J. opn1lw1 . H. and K. opn1lw2 . I. rod opsin ( RH1 ). White boxes, DMSO; gray boxes, at-RA (both in embryonic eye tissues); dark gray boxes, 9-cis RA (in whole embryos). In the boxplots, the boxes demarcate the 25 th and 75 th percentiles, dark horizontal lines designate the medians, and whiskers represent the upper and lower limits. Genes in A-C, E-G, were all identified as upregulated by the microarray; dkk1b was identified as downregulated; opn1w2 and rod opsin were not detected as differentially expressed. ***, p<0.001; **, p<0.01; *, p<0.05 (2-tailed Student’s t-test).
    Figure Legend Snippet: A. cyp26b1 . B. hoxb6a . C. socs3a . D. dkk1b . E. sfrp1a . F. wnt 11 . G. and J. opn1lw1 . H. and K. opn1lw2 . I. rod opsin ( RH1 ). White boxes, DMSO; gray boxes, at-RA (both in embryonic eye tissues); dark gray boxes, 9-cis RA (in whole embryos). In the boxplots, the boxes demarcate the 25 th and 75 th percentiles, dark horizontal lines designate the medians, and whiskers represent the upper and lower limits. Genes in A-C, E-G, were all identified as upregulated by the microarray; dkk1b was identified as downregulated; opn1w2 and rod opsin were not detected as differentially expressed. ***, p<0.001; **, p<0.01; *, p<0.05 (2-tailed Student’s t-test).

    Techniques Used: Microarray

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    Article Title: NDRG1 upregulation by ubiquitin proteasome system dysfunction aggravates neurodegeneration.
    Article Snippet: Using the approximately 400 motor neurons collected from each genotype, we performed the microarray analysis (Affymetrix GeneChip Mouse Genome 430 2.0 Array), and 23 genes (Gtsf1, Ptrf, Xaf1, Pip4k2b, Ndrg1, 1700029l15Rik, Marchf3, Zfp397, Cacul1, Orai1, Dffb, Lpcat3, Tlk2, Slc48a1, Zkscan8, C79468, Swt1, Emp1, Tmem41b, Fam53b, Ak1, Nudt5, and Gulp1) were significantly changed by more than two-fold in Psmc4 CKO mice (Fig. 1C and D).

    Article Title: Differentiation of human T follicular helper cells in vitro requires co-operation between STAT3 and SMAD signaling cytokines that is restrained by IL-2
    Article Snippet: For samples used for microarray analysis, Superscript3 III First-Strand Synthesis System (Thermofisher) was used, all as per manufacturer’s instructions.

    Article Title: NDRG1 upregulation by ubiquitin proteasome system dysfunction aggravates neurodegeneration
    Article Snippet: Using the approximately 400 motor neurons collected from each genotype, we performed the microarray analysis (Affymetrix GeneChip Mouse Genome 430 2.0 Array), and 23 genes ( Gtsf1 , Ptrf , Xaf1 , Pip4k2b , Ndrg1 , 1700029l15Rik , Marchf3 , Zfp397 , Cacul1 , Orai1 , Dffb , Lpcat3 , Tlk2 , Slc48a1 , Zkscan8 , C79468 , Swt1 , Emp1 , Tmem41b , Fam53b , Ak1 , Nudt5 , and Gulp1 ) were significantly changed by more than two-fold in Psmc4 CKO mice (Fig. C and D).

    Article Title: Prenatal diagnosis of 9q34.3 microdeletion-associated Kleefstra syndrome in a pregnancy complicated by polyhydramnios: A case report and literature review.
    Article Snippet: One de novo microdeletion segment was confirmed by single nucleotide polymorphism (SNP)-based Affymetrix 750 K microarray analysis: 2.10-Mb deletion in 9q34.3 (chr9: 138,915,822e141,018,648) (Fig. 1(E)).

    Article Title: A novel amphiphilic squalene-based compound with open-chain polyethers reduces malignant melanoma metastasis in-vitro and in-vivo
    Article Snippet: Microarray analysis was performed on the Affymetrix’s GeneAtlas® System (Affymetrix Inc, USA).

    Article Title: Mitochondrial defects and metabolic vulnerabilities in Lynch syndrome-associated MSH2-deficient endometrial cancer
    Article Snippet: We profiled an initial cohort of Msh2KO tumors (n = 7) and Msh2KO mice with benign endometrium (n = 6) compared to age-matched control mice (n = 4) using transcriptomic profiling of microdissected glands via microarray analysis (Clariom D, Affymetrix).

    Immunofluorescence:

    Article Title: Absence of Aquaporin-4 (AQP4) Prolongs the Presence of a CD11c+ Microglial Population during Postnatal Corpus Callosum Development
    Article Snippet: .. Here, using diverse experimental approximations, such as immunofluorescence, microarray analysis (Affymetrix, Santa Clara, CA, USA), RT-qPCR and in situ hybridisation, we came to the same result, which is the confirmation that a CD11c+ microglial cell population appears and remains on the CC tissue of the AQP4-KO animals for a longer time and at higher levels than those detected in the CC of WT animals. ..

    Microarray:

    Article Title: Absence of Aquaporin-4 (AQP4) Prolongs the Presence of a CD11c+ Microglial Population during Postnatal Corpus Callosum Development
    Article Snippet: .. Here, using diverse experimental approximations, such as immunofluorescence, microarray analysis (Affymetrix, Santa Clara, CA, USA), RT-qPCR and in situ hybridisation, we came to the same result, which is the confirmation that a CD11c+ microglial cell population appears and remains on the CC tissue of the AQP4-KO animals for a longer time and at higher levels than those detected in the CC of WT animals. ..

    Article Title: Polyploidy Promotes Hypertranscription, Apoptosis Resistance, and Ciliogenesis in Cancer Cells and Mesenchymal Stem Cells of Various Origins: Comparative Transcriptome In Silico Study.
    Article Snippet: .. Gene expression profile for diploid and tetraploid cells were evaluated using microarray analysis (Affymetrix, Applied Biosystems). .. Microarray data are available at the Gene Expression Omnibus (GEO) website, accession number GSE39410. (2) In the database containing the data obtained with freshly isolated cardiac interstitial cells of the mouse [31], the authors performed cell sorting by ploidy levels, using BD FACSAria II sorting and analyzed the data with FLOWJO.

    Quantitative RT-PCR:

    Article Title: Absence of Aquaporin-4 (AQP4) Prolongs the Presence of a CD11c+ Microglial Population during Postnatal Corpus Callosum Development
    Article Snippet: .. Here, using diverse experimental approximations, such as immunofluorescence, microarray analysis (Affymetrix, Santa Clara, CA, USA), RT-qPCR and in situ hybridisation, we came to the same result, which is the confirmation that a CD11c+ microglial cell population appears and remains on the CC tissue of the AQP4-KO animals for a longer time and at higher levels than those detected in the CC of WT animals. ..

    In Situ:

    Article Title: Absence of Aquaporin-4 (AQP4) Prolongs the Presence of a CD11c+ Microglial Population during Postnatal Corpus Callosum Development
    Article Snippet: .. Here, using diverse experimental approximations, such as immunofluorescence, microarray analysis (Affymetrix, Santa Clara, CA, USA), RT-qPCR and in situ hybridisation, we came to the same result, which is the confirmation that a CD11c+ microglial cell population appears and remains on the CC tissue of the AQP4-KO animals for a longer time and at higher levels than those detected in the CC of WT animals. ..

    Hybridization:

    Article Title: Absence of Aquaporin-4 (AQP4) Prolongs the Presence of a CD11c+ Microglial Population during Postnatal Corpus Callosum Development
    Article Snippet: .. Here, using diverse experimental approximations, such as immunofluorescence, microarray analysis (Affymetrix, Santa Clara, CA, USA), RT-qPCR and in situ hybridisation, we came to the same result, which is the confirmation that a CD11c+ microglial cell population appears and remains on the CC tissue of the AQP4-KO animals for a longer time and at higher levels than those detected in the CC of WT animals. ..

    Gene Expression:

    Article Title: Polyploidy Promotes Hypertranscription, Apoptosis Resistance, and Ciliogenesis in Cancer Cells and Mesenchymal Stem Cells of Various Origins: Comparative Transcriptome In Silico Study.
    Article Snippet: .. Gene expression profile for diploid and tetraploid cells were evaluated using microarray analysis (Affymetrix, Applied Biosystems). .. Microarray data are available at the Gene Expression Omnibus (GEO) website, accession number GSE39410. (2) In the database containing the data obtained with freshly isolated cardiac interstitial cells of the mouse [31], the authors performed cell sorting by ploidy levels, using BD FACSAria II sorting and analyzed the data with FLOWJO.



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    Thermo Fisher platform-based microarray analysis
    A. Statistical Analysis of <t>Microarray</t> (SAM) plot, at a 0.109 false discovery rate (FDR). B. Gene ontology (GO) analysis; selected GO categories shown. C. Venn diagram comparing differentially expressed genes in eyes of RA-treated embryos with those of RA-treated whole embryos during somitogenesis and with those of hearts of RA-treated larvae.
    Platform Based Microarray Analysis, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/platform-based+microarray+analysis/pmc04546582-389-10-8
    Average 90 stars, based on 1 article reviews
    platform-based microarray analysis - by Bioz Stars, 2026-09
    90/100 stars
      Buy from Supplier

    Image Search Results


    A. Statistical Analysis of Microarray (SAM) plot, at a 0.109 false discovery rate (FDR). B. Gene ontology (GO) analysis; selected GO categories shown. C. Venn diagram comparing differentially expressed genes in eyes of RA-treated embryos with those of RA-treated whole embryos during somitogenesis and with those of hearts of RA-treated larvae.

    Journal: PLoS Genetics

    Article Title: Retinoic Acid Signaling Regulates Differential Expression of the Tandemly-Duplicated Long Wavelength-Sensitive Cone Opsin Genes in Zebrafish

    doi: 10.1371/journal.pgen.1005483

    Figure Lengend Snippet: A. Statistical Analysis of Microarray (SAM) plot, at a 0.109 false discovery rate (FDR). B. Gene ontology (GO) analysis; selected GO categories shown. C. Venn diagram comparing differentially expressed genes in eyes of RA-treated embryos with those of RA-treated whole embryos during somitogenesis and with those of hearts of RA-treated larvae.

    Article Snippet: The data were compared to those obtained using Affymetrix platform-based microarray analysis of RA treatments in zebrafish embryos, over different developmental times or in different tissues [ , ].

    Techniques: Microarray

    A. cyp26b1 . B. hoxb6a . C. socs3a . D. dkk1b . E. sfrp1a . F. wnt 11 . G. and J. opn1lw1 . H. and K. opn1lw2 . I. rod opsin ( RH1 ). White boxes, DMSO; gray boxes, at-RA (both in embryonic eye tissues); dark gray boxes, 9-cis RA (in whole embryos). In the boxplots, the boxes demarcate the 25 th and 75 th percentiles, dark horizontal lines designate the medians, and whiskers represent the upper and lower limits. Genes in A-C, E-G, were all identified as upregulated by the microarray; dkk1b was identified as downregulated; opn1w2 and rod opsin were not detected as differentially expressed. ***, p<0.001; **, p<0.01; *, p<0.05 (2-tailed Student’s t-test).

    Journal: PLoS Genetics

    Article Title: Retinoic Acid Signaling Regulates Differential Expression of the Tandemly-Duplicated Long Wavelength-Sensitive Cone Opsin Genes in Zebrafish

    doi: 10.1371/journal.pgen.1005483

    Figure Lengend Snippet: A. cyp26b1 . B. hoxb6a . C. socs3a . D. dkk1b . E. sfrp1a . F. wnt 11 . G. and J. opn1lw1 . H. and K. opn1lw2 . I. rod opsin ( RH1 ). White boxes, DMSO; gray boxes, at-RA (both in embryonic eye tissues); dark gray boxes, 9-cis RA (in whole embryos). In the boxplots, the boxes demarcate the 25 th and 75 th percentiles, dark horizontal lines designate the medians, and whiskers represent the upper and lower limits. Genes in A-C, E-G, were all identified as upregulated by the microarray; dkk1b was identified as downregulated; opn1w2 and rod opsin were not detected as differentially expressed. ***, p<0.001; **, p<0.01; *, p<0.05 (2-tailed Student’s t-test).

    Article Snippet: The data were compared to those obtained using Affymetrix platform-based microarray analysis of RA treatments in zebrafish embryos, over different developmental times or in different tissues [ , ].

    Techniques: Microarray