computer program origin 3.5 (OriginLab corp)
90
Structured Review
OriginLab corp
computer program origin 3.5
Computer Program Origin 3.5, supplied by OriginLab corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/origin+computer+program/computer+program+origin+3+5/pm26741746-190-37-50
Average 90 stars, based on 1 article reviews
Computer Program Origin 3.5, supplied by OriginLab corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/origin+computer+program/computer+program+origin+3+5/pm26741746-190-37-50
Average 90 stars, based on 1 article reviews
computer program origin 3.5 - by Bioz Stars,
2026-09
90/100 stars
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other:Article Title: Anticonvulsants Based on the α-Substituted Amide Group Pharmacophore Bind to and Inhibit Function of Neuronal Nicotinic Acetylcholine Receptors. Article Snippet: Although the antiepileptic properties of α-substituted lactams, acetamides, and cyclic imides have been known for over 60 years, the mechanism by which they act remains unclear.. I report here that these compounds bind to the nicotinic acetylcholine receptor (nAChR) and inhibit its function.. Using transient kinetic measurements with functionally active, nondesensitized receptors, I have discovered that (i) α-substituted lactams and cyclic imides are noncompetitive inhibitors of heteromeric subtypes (such as α4β2 and α3β4) of neuronal nAChRs and (ii) the binding affinity of these compounds toward the nAChR correlates with their potency in preventing maximal electroshock (MES)-induced convulsions in mice. |