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mammaprint, a microarray gene expression analysis  (Agendia BV)

 
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    Structured Review

    Agendia BV mammaprint, a microarray gene expression analysis
    Mammaprint, A Microarray Gene Expression Analysis, supplied by Agendia BV, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/microarray+gene+expression+analysis/mammaprint+assay/pm39602125-66-0-9
    Average 90 stars, based on 1 article reviews
    mammaprint, a microarray gene expression analysis - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Expressing:

    Article Title: Customized assays for personalized cancer monitoring
    Article Snippet: .. For example, the MammaPrint assay from Agendia analyzes the expression of a panel of genes and provides a score that is associated with the risk of recurrence in a particular patient. .. Alternatively, or additionally, the BluePrint assay from Agendia analyzes the expression of a panel of genes and provides an accurate classification of an individual breast cancer's subtype, such as, for example, luminal-type, HER2-type, or basal-type.

    other:

    Article Title: Pathologic complete response (pCR) rates for patients with HR+/HER2− high-risk, early-stage breast cancer (EBC) by clinical and molecular features in the phase II I-SPY2 clinical trial
    Article Snippet: 14 Using the expression data generated, MammaPrint (MP) risk categorization, BluePrint (BP) subtypes, and ImPrint classifications were evaluated by Agendia Inc. as previously described.

    Article Title: Genetic and clinical landscape of ER + /PR- breast cancer in China
    Article Snippet: Genecast Biotechnology has obtained the authorization of MammaPrint® and BluePrint® assays by Agendia N.V. and Agendia, Inc. All analyses were done blinded to clinical and pathological information.

    Article Title: Do circulating neutrophil extracellular traps predict recurrence in early breast cancer?
    Article Snippet: Genomic signatures such as the Oncotype Dx recurrence score (RS) (Genomic Health), PAM50-based Prosigna risk of recurrence (ROR) (NanoString), Breast Cancer Index (BCI) (bioTheranostics), EndoPredict (EPclin) (Myriad Genetics), and MammaPrint 70-gene signature (Agendia BV) have been proven helpful in identifying patients with HR+ BC who are at increased risk of recurrence and may benefit from adjuvant chemotherapy ( ).

    Article Title: Genetic and clinical landscape of ER + /PR- breast cancer in China.
    Article Snippet: Genecast Biotechnology has obtained the authorization of MammaPrint® and BluePrint® assays by Agendia N.V. and Agendia, Inc. All analyses were done blinded to clinical and pathological information.

    Gene Expression:

    Article Title: MammaPrint Genomic Assay Providing Prognostic Information in Early Breast Cancer: 10-Year Follow-Up From a Retrospective German Breast Cancer Registry Analysis
    Article Snippet: .. Introduction: Gene expression assays, such as the MammaPrint® (Agendia, Amsterdam, the Netherlands) 70-gene signature, are increasingly used by oncologists to understand breast cancer biology and improve treatment planning. ..

    Article Title: Dissecting Biological Risk Using Genomic Assays-Implications for Extended Endocrine Therapy and Beyond.
    Article Snippet: .. MammaPrint, a microarray gene expression analysis, was performed at Agendia Inc.38-41 Samples contained 30% tumor cells or greater, and extracted RNA from formalin-fixed paraffin-embedded tissue was converted to cDNA, amplified, labeled, and hybridized onto Agendia’s diagnostic arrays (custom-designed, Agilent Technologies). ..

    Microarray:

    Article Title: Dissecting Biological Risk Using Genomic Assays-Implications for Extended Endocrine Therapy and Beyond.
    Article Snippet: .. MammaPrint, a microarray gene expression analysis, was performed at Agendia Inc.38-41 Samples contained 30% tumor cells or greater, and extracted RNA from formalin-fixed paraffin-embedded tissue was converted to cDNA, amplified, labeled, and hybridized onto Agendia’s diagnostic arrays (custom-designed, Agilent Technologies). ..

    Formalin-fixed Paraffin-Embedded:

    Article Title: Dissecting Biological Risk Using Genomic Assays-Implications for Extended Endocrine Therapy and Beyond.
    Article Snippet: .. MammaPrint, a microarray gene expression analysis, was performed at Agendia Inc.38-41 Samples contained 30% tumor cells or greater, and extracted RNA from formalin-fixed paraffin-embedded tissue was converted to cDNA, amplified, labeled, and hybridized onto Agendia’s diagnostic arrays (custom-designed, Agilent Technologies). ..

    Amplification:

    Article Title: Dissecting Biological Risk Using Genomic Assays-Implications for Extended Endocrine Therapy and Beyond.
    Article Snippet: .. MammaPrint, a microarray gene expression analysis, was performed at Agendia Inc.38-41 Samples contained 30% tumor cells or greater, and extracted RNA from formalin-fixed paraffin-embedded tissue was converted to cDNA, amplified, labeled, and hybridized onto Agendia’s diagnostic arrays (custom-designed, Agilent Technologies). ..

    Labeling:

    Article Title: Dissecting Biological Risk Using Genomic Assays-Implications for Extended Endocrine Therapy and Beyond.
    Article Snippet: .. MammaPrint, a microarray gene expression analysis, was performed at Agendia Inc.38-41 Samples contained 30% tumor cells or greater, and extracted RNA from formalin-fixed paraffin-embedded tissue was converted to cDNA, amplified, labeled, and hybridized onto Agendia’s diagnostic arrays (custom-designed, Agilent Technologies). ..

    Diagnostic Assay:

    Article Title: Dissecting Biological Risk Using Genomic Assays-Implications for Extended Endocrine Therapy and Beyond.
    Article Snippet: .. MammaPrint, a microarray gene expression analysis, was performed at Agendia Inc.38-41 Samples contained 30% tumor cells or greater, and extracted RNA from formalin-fixed paraffin-embedded tissue was converted to cDNA, amplified, labeled, and hybridized onto Agendia’s diagnostic arrays (custom-designed, Agilent Technologies). ..



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    NAC61 expression analysis. (A) NAC61 expression behavior in grapevine organs throughout development (bar plot) and compared in the heatmap (logarithmic value) with that of NAC60 and NAC33. The data were retrieved from the atlas transcriptomic dataset of cv. ‘Corvina’ ( Fasoli et al ., 2012 ). Each value represents the mean ±SD of three biological replicates. (B) Correlation between NAC61 expression level and sugar content in grape berries sampled from fruit set to maturity in cv. ‘Cabernet Sauvignon’ and cv. ‘Pinot noir’ ( Fasoli et al ., 2018 ). The black line represents the trend of the averaged values of the two varieties. The R 2 values shown correspond to the fitting of different polynomial regressions to each corresponding group of samples (orange for cv. ‘Cabernet Sauvignon’ samples, blue for cv. ‘Pinot noir’ samples, and black for the entire set of samples). (C) Correlation between NAC61 expression level and sugar content in grape berries sampled during post-harvest dehydration in six different varieties ( Zenoni et al ., 2016 ). (D) Correlation between NAC61 expression level and berry weight loss in cv. ‘Corvina’ berries sampled during traditional long and forced short post-harvest dehydration processes ( Zenoni et al ., 2020 ). Expression values were determined by <t>microarray</t> analysis and each value represents the mean ±SD from three biological replicates. (E) NAC61 GCNs based on berry, leaf, and tissue-independent (TI) datasets. Left, Venn diagram showing exclusive and shared genes based on the three datasets; right, three-dimensional plot of co-expressed genes in which NAC, WRKY, and ZIP family members already described as having involvement in berry ripening and/or stress responses are indicated.
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    Summary of apoptosis pathways in human and Oncopig cells. Summarized apoptotic pathways altered by gemcitabine treatment in Oncopig BCCL and 5637 cells evaluated by <t>microarray.</t> There were multiple possible cellular pathways involved in apoptosis induction, such as: TP53INP1/P53/BCL/BAX/CASPASE mitochondrial intrinsical pathway; TP53INP1/TP73 activation; FAS/RB1/GADD45B/CASPASE pathway and cell rounding up by RND1 and/or ZMYM6.
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    Image Search Results


    NAC61 expression analysis. (A) NAC61 expression behavior in grapevine organs throughout development (bar plot) and compared in the heatmap (logarithmic value) with that of NAC60 and NAC33. The data were retrieved from the atlas transcriptomic dataset of cv. ‘Corvina’ ( Fasoli et al ., 2012 ). Each value represents the mean ±SD of three biological replicates. (B) Correlation between NAC61 expression level and sugar content in grape berries sampled from fruit set to maturity in cv. ‘Cabernet Sauvignon’ and cv. ‘Pinot noir’ ( Fasoli et al ., 2018 ). The black line represents the trend of the averaged values of the two varieties. The R 2 values shown correspond to the fitting of different polynomial regressions to each corresponding group of samples (orange for cv. ‘Cabernet Sauvignon’ samples, blue for cv. ‘Pinot noir’ samples, and black for the entire set of samples). (C) Correlation between NAC61 expression level and sugar content in grape berries sampled during post-harvest dehydration in six different varieties ( Zenoni et al ., 2016 ). (D) Correlation between NAC61 expression level and berry weight loss in cv. ‘Corvina’ berries sampled during traditional long and forced short post-harvest dehydration processes ( Zenoni et al ., 2020 ). Expression values were determined by microarray analysis and each value represents the mean ±SD from three biological replicates. (E) NAC61 GCNs based on berry, leaf, and tissue-independent (TI) datasets. Left, Venn diagram showing exclusive and shared genes based on the three datasets; right, three-dimensional plot of co-expressed genes in which NAC, WRKY, and ZIP family members already described as having involvement in berry ripening and/or stress responses are indicated.

    Journal: Journal of Experimental Botany

    Article Title: NAC61 regulates late- and post-ripening osmotic, oxidative, and biotic stress responses in grapevine

    doi: 10.1093/jxb/erad507

    Figure Lengend Snippet: NAC61 expression analysis. (A) NAC61 expression behavior in grapevine organs throughout development (bar plot) and compared in the heatmap (logarithmic value) with that of NAC60 and NAC33. The data were retrieved from the atlas transcriptomic dataset of cv. ‘Corvina’ ( Fasoli et al ., 2012 ). Each value represents the mean ±SD of three biological replicates. (B) Correlation between NAC61 expression level and sugar content in grape berries sampled from fruit set to maturity in cv. ‘Cabernet Sauvignon’ and cv. ‘Pinot noir’ ( Fasoli et al ., 2018 ). The black line represents the trend of the averaged values of the two varieties. The R 2 values shown correspond to the fitting of different polynomial regressions to each corresponding group of samples (orange for cv. ‘Cabernet Sauvignon’ samples, blue for cv. ‘Pinot noir’ samples, and black for the entire set of samples). (C) Correlation between NAC61 expression level and sugar content in grape berries sampled during post-harvest dehydration in six different varieties ( Zenoni et al ., 2016 ). (D) Correlation between NAC61 expression level and berry weight loss in cv. ‘Corvina’ berries sampled during traditional long and forced short post-harvest dehydration processes ( Zenoni et al ., 2020 ). Expression values were determined by microarray analysis and each value represents the mean ±SD from three biological replicates. (E) NAC61 GCNs based on berry, leaf, and tissue-independent (TI) datasets. Left, Venn diagram showing exclusive and shared genes based on the three datasets; right, three-dimensional plot of co-expressed genes in which NAC, WRKY, and ZIP family members already described as having involvement in berry ripening and/or stress responses are indicated.

    Article Snippet: The cDNA synthesis, labelling, hybridization, and washing steps were performed according to the Agilent Microarray-Based Gene Expression Analysis Guide ( https://www.agilent.com/cs/library/usermanuals/Public/G4140-90040_GeneExpression_OneColor_6.9.pdf ).

    Techniques: Expressing, Microarray

    Summary of apoptosis pathways in human and Oncopig cells. Summarized apoptotic pathways altered by gemcitabine treatment in Oncopig BCCL and 5637 cells evaluated by microarray. There were multiple possible cellular pathways involved in apoptosis induction, such as: TP53INP1/P53/BCL/BAX/CASPASE mitochondrial intrinsical pathway; TP53INP1/TP73 activation; FAS/RB1/GADD45B/CASPASE pathway and cell rounding up by RND1 and/or ZMYM6.

    Journal: Frontiers in Oncology

    Article Title: Oncopig bladder cancer cells recapitulate human bladder cancer treatment responses in vitro

    doi: 10.3389/fonc.2024.1323422

    Figure Lengend Snippet: Summary of apoptosis pathways in human and Oncopig cells. Summarized apoptotic pathways altered by gemcitabine treatment in Oncopig BCCL and 5637 cells evaluated by microarray. There were multiple possible cellular pathways involved in apoptosis induction, such as: TP53INP1/P53/BCL/BAX/CASPASE mitochondrial intrinsical pathway; TP53INP1/TP73 activation; FAS/RB1/GADD45B/CASPASE pathway and cell rounding up by RND1 and/or ZMYM6.

    Article Snippet: To obtain the gene transcription panel of treated and untreated human and Oncopig cells, the Two-Color Microarray-Based Gene Expression Analysis microarrays (Agilent Technologies Inc, Santa Clara, CA, USA) were used according to the manufacturer’s instructions.

    Techniques: Microarray, Activation Assay