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ice deconvolution algorithm (Synthego Inc)

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Synthego Inc ice deconvolution algorithm
Ice Deconvolution Algorithm, supplied by Synthego Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/deconvolution+algorithms/algorithm+deconvolution+ice/pm41419196-192-14-17
Average 86 stars, based on 1 article reviews

ice deconvolution algorithm - by Bioz Stars, 2026-09

86/100 stars

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Produced:

Article Title: Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease
Article Snippet: .. Synthego ICE indel deconvolution web-based tool ( https://synthego.com ) was then used to determine the indels that were produced at the sgRNA target site. ..

Sequencing:

Article Title: NEUROG3 Is Sufficient to Drive Neuroendocrine Differentiation in Prostate Cancer Cells
Article Snippet: .. Sequence analysis confirmed indels at the target site, and Synthego ICE deconvolution verified high editing efficiency and frameshift disruption resulting in premature stop codons (Supplementary Figure S3A). ..

Article Title: A protective cGAMP-mediated anti-tumor immune response can proceed without LRRC8/VRAC channels.
Article Snippet: Cells were transfected using Lipofectamine 2000 (Invitrogen, 11668019), and single-cell FACS of GFP-positive cells was performed with a FACSAria II or FACSAria III (BD Bioscience) device. .. Gene editing in arising monoclonal cell lines was validated by Sanger sequencing using the ICE deconvolution algorithm (Synthego). ..

Article Title: A protective cGAMP-mediated anti-tumor immune response can proceed without LRRC8/VRAC channels
Article Snippet: Cells were transfected using Lipofectamine 2000 (Invitrogen, 11668019), and single-cell FACS of GFP-positive cells was performed with a FACSAria II or FACSAria III (BD Bioscience) device. .. Gene editing in arising monoclonal cell lines was validated by Sanger sequencing using the ICE deconvolution algorithm (Synthego). ..

Disruption:

CRISPR:

Article Title: PTPN2-KO CAR-T Cells Demonstrate Enhanced Effector Function, CNS Infiltration, and Toxicity in a Non-Human Primate CAR-T Model
Article Snippet: .. We first identified a CRISPR/Cas9 guide that would selectively and effectively delete PTPN2 in primary human T-cells in a region with low homology to PTPN1 ( Supplemental Fig.1A-B ), achieving a mean editing efficiency of 73.5+/-2.9% in primary T and CAR-T cells measured by interference analysis using Synthego ICE deconvolution ( , Supplemental Fig.1A) and transcriptional analysis (Supplemental Fig.1B) . ..