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computer-generated block randomization schedule  (Glaxo Smith)

 
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    Structured Review

    Glaxo Smith computer-generated block randomization schedule
    Computer Generated Block Randomization Schedule, supplied by Glaxo Smith, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/computer-generated+block+randomization+schedule/computer+generated+randomization+schedule/pm22103635-89-22-29
    Average 90 stars, based on 1 article reviews
    computer-generated block randomization schedule - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Sequencing:

    Article Title: Drugs for the acute treatment of migraine in children and adolescents
    Article Snippet: .. Random sequence generation (selection bias) , Low risk , Quote: "randomized in a 1:1:1 ratio (in blocks of six) to one of three treatment groups"; "computer‐generated randomization schedule" Comment: previous migraine studies by GlaxoSmithKline have documented acceptable sequence generation (e.g. Winner 2000 ). .. Allocation concealment (selection bias) , Low risk , Quote: "randomization schedule prepared by the sponsor" Comment: centralized allocation.

    Article Title: Vaccines for preventing rotavirus diarrhoea: vaccines in use
    Article Snippet: Seroconversion: appearance of anti-rotavirus IgA antibody concentration ≥ 20 U/mL in participants seronegative for rotavirus before vaccination (review includes data from 1 to 2 months after dose 2) Immunization status Concomitant vaccines included 7 valent pneumococcal polysaccharide conjugate vaccine (Prevenar) and meningococcal group c conjugate vaccine (Meningitec); Hepatitis B vaccine, diphtheria-tetanusacellular pertussis, polio virus, and H. influenzae type b vaccines were co-administered Location 98 centres in 6 European countries (Czech Republic, Finland, France, Germany, Italy, and Spain) WHO mortality stratum A Notes Date: 12 February 2007 to 08 August 2007 Source of funding: funded by GlaxoSmithKline Biologicals Other: vaccination postponed if baby either had a temperature of ≥ 37.5 °C (axillary) or of 38.0 °C (rectal) or had gastroenteritis within 7 days before planned vaccination Study aim: "to assess the efficacy and safety of HRV [RV1] vaccine during the 3rd year of age in subjects primed with a 2-dose schedule in study 102247, with the first dose administered at the age of 6 to 14 weeks" .. Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Quote: "GSK Biologicals provided vaccine supplies that were numbered with a computer-generated randomization list" Allocation concealment (selection bias) Low risk Quote: "randomization was done by a central Internet randomization system. ..

    Article Title: Tafenoquine for preventing relapse in people with Plasmodium vivax malaria
    Article Snippet: .. Random sequence generation (selection bias) , Low risk , Quote: "With the use of a computer‐generated randomisation schedule provided by GlaxoSmithKline, on day 1 eligible participants were randomly assigned, in a 2:1:1 ratio...". .. Allocation concealment (selection bias) , Low risk , Quote: "Patients and trial staff were unaware of the group assignments.".

    Selection:

    Article Title: Drugs for the acute treatment of migraine in children and adolescents
    Article Snippet: .. Random sequence generation (selection bias) , Low risk , Quote: "randomized in a 1:1:1 ratio (in blocks of six) to one of three treatment groups"; "computer‐generated randomization schedule" Comment: previous migraine studies by GlaxoSmithKline have documented acceptable sequence generation (e.g. Winner 2000 ). .. Allocation concealment (selection bias) , Low risk , Quote: "randomization schedule prepared by the sponsor" Comment: centralized allocation.

    Article Title: Vaccines for preventing rotavirus diarrhoea: vaccines in use
    Article Snippet: Seroconversion: appearance of anti-rotavirus IgA antibody concentration ≥ 20 U/mL in participants seronegative for rotavirus before vaccination (review includes data from 1 to 2 months after dose 2) Immunization status Concomitant vaccines included 7 valent pneumococcal polysaccharide conjugate vaccine (Prevenar) and meningococcal group c conjugate vaccine (Meningitec); Hepatitis B vaccine, diphtheria-tetanusacellular pertussis, polio virus, and H. influenzae type b vaccines were co-administered Location 98 centres in 6 European countries (Czech Republic, Finland, France, Germany, Italy, and Spain) WHO mortality stratum A Notes Date: 12 February 2007 to 08 August 2007 Source of funding: funded by GlaxoSmithKline Biologicals Other: vaccination postponed if baby either had a temperature of ≥ 37.5 °C (axillary) or of 38.0 °C (rectal) or had gastroenteritis within 7 days before planned vaccination Study aim: "to assess the efficacy and safety of HRV [RV1] vaccine during the 3rd year of age in subjects primed with a 2-dose schedule in study 102247, with the first dose administered at the age of 6 to 14 weeks" .. Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Quote: "GSK Biologicals provided vaccine supplies that were numbered with a computer-generated randomization list" Allocation concealment (selection bias) Low risk Quote: "randomization was done by a central Internet randomization system. ..

    Article Title: Tafenoquine for preventing relapse in people with Plasmodium vivax malaria
    Article Snippet: .. Random sequence generation (selection bias) , Low risk , Quote: "With the use of a computer‐generated randomisation schedule provided by GlaxoSmithKline, on day 1 eligible participants were randomly assigned, in a 2:1:1 ratio...". .. Allocation concealment (selection bias) , Low risk , Quote: "Patients and trial staff were unaware of the group assignments.".

    other:

    Article Title: A phase 2a, randomized, crossover trial of gabapentin enacarbil for the treatment of postherpetic neuralgia in gabapentin inadequate responders.
    Article Snippet: The computer-generated randomization schedule (block size 4) was stratified by center and provided by GlaxoSmithKline (Research Triangle Park, NC, USA).

    Article Title: Single-Dose Tafenoquine to Prevent Relapse ofPlasmodium vivaxMalaria
    Article Snippet: With the use of a computer-generated randomization schedule provided by GlaxoSmithKline, on day 1 eligible participants were randomly assigned, in a 2:1:1 ratio, to receive tafenoquine, primaquine, or placebo.

    Article Title: Tocolytics for delaying preterm birth: a network meta-analysis (0924)
    Article Snippet: Funded by GlaxoSmithKline Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Computer-generated randomisation Allocation concealment (selection bias) Low risk Infusions and matching placebos were prepared by unblinded pharmacists/qualified individuals Saade 2021 Tocolytics for delaying preterm birth: a network meta-analysis (0924) (Review) Copyright © 2022 The Cochrane Collaboration.

    Article Title: Safety and efficacy of ozanezumab in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled, phase 2 trial
    Article Snippet: Patients were randomised centrally across all sites in accordance with a computer-generated randomisation schedule validated by GlaxoSmithKline.



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