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Med Associates Inc
computer program
Computer Program, supplied by Med Associates Inc, used in various techniques. Bioz Stars score: 93/100, based on 61 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/computer+software+package/Computer+Package/pm40389584-54-22-29
Average 93 stars, based on 61 article reviews
Computer Program, supplied by Med Associates Inc, used in various techniques. Bioz Stars score: 93/100, based on 61 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/computer+software+package/Computer+Package/pm40389584-54-22-29
Average 93 stars, based on 61 article reviews
computer program - by Bioz Stars,
2026-09
93/100 stars
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other:Article Title: In Vitro and In Vivo Pharmacological Characterization of Fentanyl Analogs Article Snippet: Each Article Title: Reward expectation and receipt differentially modulate the spiking of accumbens D1+ and D2+ neurons. Article Snippet: Pretraining and testing were performed in Article Title: β-Nicotyrine and e-cigarette abuse liability I: Pharmacodynamics and interaction with pharmacokinetics and discriminative stimulus effects of nicotine in rats. Article Snippet: Background: β-Nicotyrine (β-Nic) is a prevalent minor alkaloid in electronic nicotine delivery systems (ENDS) aerosols.. High doses of β-Nic slow nicotine (Nic) metabolism in mice, suggesting it may alter the abuse liability of ENDS.. Thus, the present study examined the pharmacokinetics and pharmacodynamics of β-Nic and Nic, both alone and in combination, including the ability of β-Nic to produce nicotine-like discriminative-stimulus (i.e., subjective) effects and/or enhance the effects of Nic in rats. Article Title: Parvalbumin interneurons gate and shape striatal sequences Article Snippet: Bandit task pretraining and testing were performed in Article Title: Effects of the veterinary anesthetic xylazine on the discriminative stimulus and rate-decreasing effects of fentanyl in rats Article Snippet: Purpose: Adulterants such as the α2-adrenoreceptor agonist xylazine in the illicit drug supply can complicate overdose and treatment plans for patients.. Xylazine and other α2-adrenoreceptor agonists are reported to extend the duration of the μ opioid receptor agonist fentanyl which is short acting relative to other opioids (Friedman et al., 2022; Meert and De Kock, 1994).. Methods: To test the effects of xylazine on the subjective effects of fentanyl, 12 Sprague-Dawley rats were trained to discriminate between saline or 0.01 mg/kg fentanyl in a two-lever drug discrimination procedure. Article Title: The Sigma 1 receptor antagonist CM304 potentiates the antinociceptive effects of the cannabinoid receptor agonist delta 9 -tetrahydrocannabinol in rats and mice. Article Snippet: 1 Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX 79106, USA 2 Department of Medicinal Chemistry, College of Pharmacy, University of Florida, 1225 Center Drive, PO Box 100484, Gainesville, FL 32610, USA 3 Department of Drug and Health Sciences, University of Catania, viale A. Doria 6, Catania 95125, Italy 4 Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA 5 College of Pharmacy, University of South Carolina, Columbia, SC 29208, USA 6 Department of Pharmacology, Joe R. and Teresa Lozano Long School of Medicine, University of Texas Health San Antonio, San Antonio, TX 78229, USA 7 Translational Drug Development Core, Clinical and Translational Sciences Institute, University of Florida, Gainesville, FL 32610, USA Abstract Background Mu opioid receptor (MOR) agonists are the primary medication class used to treat moderate to severe pain; however, the ongoing opioid overdose crisis underscores the need for alternatives to MOR agonists for pain treatment.. Delta9-tetrahydrocannabinol (THC), a cannabinoid CB1 receptor (CB1R) agonist, and sigma1 receptor (σ1R) antagonists elicit antinociceptive effects albeit less effectively than MOR agonists.. Co-administration of σ1R antagonists with THC may offer a safer alternative for pain management. Activity Assay:Article Title: Preconceptual paternal ethanol drinking induces sexually dimorphic behavioural changes across 2 generations Article Snippet: .. An animal was then placed into the centre of each chamber and activity was recorded for 60 min and processed by a Article Title: Preconceptual paternal ethanol drinking induces sexually dimorphic behavioural changes across 2 generations. Article Snippet: .. An animal was then placed into the centre of each chamber and activity was recorded for 60 min and processed by a |