alpha cpu-based linux systems (Molecular Dynamics Inc)
90
Structured Review
Molecular Dynamics Inc
alpha cpu-based linux systems
Alpha Cpu Based Linux Systems, supplied by Molecular Dynamics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/alpha+cpu-based+linux+systems/alpha+cpu+based+linux+systems/pm10985766-165-17-0
Average 90 stars, based on 1 article reviews
Alpha Cpu Based Linux Systems, supplied by Molecular Dynamics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/alpha+cpu-based+linux+systems/alpha+cpu+based+linux+systems/pm10985766-165-17-0
Average 90 stars, based on 1 article reviews
alpha cpu-based linux systems - by Bioz Stars,
2026-09
90/100 stars
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other:Article Title: Interactions of conformationally biased north and south 2'-fluoro-2', 3'-dideoxynucleoside 5'-triphosphates with the active site of HIV-1 reverse transcriptase. Article Snippet: Molecular dynamics simulations of a ternary complex of HIV-1 reverse transcriptase (RT), double-stranded DNA, and bound dideoxynucleoside-5′-triphosphate (RT-DNA-ddNTP), utilizing the ddNTPs ddATP, âFddATP, and RFddATP, explain the experimentally observed order of potency of these 5′-triphosphates as inhibitors of RT: ddATP > âFddATP > RFddATP.. On the basis of RT’s known preference to bind the incoming dNTP (or ddNTP) with a north conformation at the polymerase site, RFddATP, which in solution prefers almost exclusively a north conformation, was predicted to be the most potent inhibitor.. However, Tyr115, which appears to function as a steric gate to preclude the binding of ribonucleoside 5′-triphosphates, prevents the effective binding of RFddATP in its preferred north conformation. |