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  • 85
    OriGene trpc5 channels
    Bath application of CCK induces an inward current in HEK293 cells cotransfected with CCK2 receptors and <t>TRPC5</t> channels ( A 1 -A 4 ) whereas application of CCK had no effects in HEK293 cells transfected with TRPC5 channels alone ( B 1 -B 4 ). A 1 , Current trace from
    Trpc5 Channels, supplied by OriGene, used in various techniques. Bioz Stars score: 85/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/trpc5 channels/product/OriGene
    Average 85 stars, based on 7 article reviews
    Price from $9.99 to $1999.99
    trpc5 channels - by Bioz Stars, 2021-01
    85/100 stars
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    92
    Enzo Biochem trpc5 channel activator rosiglitazone
    Insulin response requires TRPC channel activation and PI3 kinase (A–E) Representative traces of the insulin-induced currents in the presence of the TRPC channel blocker 2-APB (100 μM) (A) or <t>TRPC5</t> channel enhancers La 3+ (100 μM) (B) and <t>rosiglitazone</t> (C and D) or PI3K inhibitor wortmannin (100 nM) (E). V hold = −60 mV. Similar to La 3+ , rosiglitazone (100 μM) potentiated insulin-activated inward currents. (F) Bar graphs summarizing the effects of Wort, 2-APB, and TRPC 4,5 channel enhancers La 3+ and rosiglitazone (100 μM) on the insulin-induced inward currents. La 3+ (100 μM) augmented the current by 5 fold and rosiglitazone (Rg) by about 2 fold. *** p
    Trpc5 Channel Activator Rosiglitazone, supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 92/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/trpc5 channel activator rosiglitazone/product/Enzo Biochem
    Average 92 stars, based on 2 article reviews
    Price from $9.99 to $1999.99
    trpc5 channel activator rosiglitazone - by Bioz Stars, 2021-01
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    92
    Hydra Biosciences trpc1 trpc5 channels
    Insulin response requires TRPC channel activation and PI3 kinase (A–E) Representative traces of the insulin-induced currents in the presence of the TRPC channel blocker 2-APB (100 μM) (A) or <t>TRPC5</t> channel enhancers La 3+ (100 μM) (B) and <t>rosiglitazone</t> (C and D) or PI3K inhibitor wortmannin (100 nM) (E). V hold = −60 mV. Similar to La 3+ , rosiglitazone (100 μM) potentiated insulin-activated inward currents. (F) Bar graphs summarizing the effects of Wort, 2-APB, and TRPC 4,5 channel enhancers La 3+ and rosiglitazone (100 μM) on the insulin-induced inward currents. La 3+ (100 μM) augmented the current by 5 fold and rosiglitazone (Rg) by about 2 fold. *** p
    Trpc1 Trpc5 Channels, supplied by Hydra Biosciences, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/trpc1 trpc5 channels/product/Hydra Biosciences
    Average 92 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    trpc1 trpc5 channels - by Bioz Stars, 2021-01
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    Anti TrpC5 MOUSE Monoclonal Antibody 200 301 G55
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    Bath application of CCK induces an inward current in HEK293 cells cotransfected with CCK2 receptors and TRPC5 channels ( A 1 -A 4 ) whereas application of CCK had no effects in HEK293 cells transfected with TRPC5 channels alone ( B 1 -B 4 ). A 1 , Current trace from

    Journal: European Journal of Pharmacology

    Article Title: Phospholipase C not protein kinase C is required for the activation of TRPC5 channels by cholecystokinin

    doi: 10.1016/j.ejphar.2012.05.032

    Figure Lengend Snippet: Bath application of CCK induces an inward current in HEK293 cells cotransfected with CCK2 receptors and TRPC5 channels ( A 1 -A 4 ) whereas application of CCK had no effects in HEK293 cells transfected with TRPC5 channels alone ( B 1 -B 4 ). A 1 , Current trace from

    Article Snippet: Briefly, a cDNA construct containing TRPC5 channels (GenBank accession number NM 012471) subcloned into pCMV6-XL4 was purchased from OriGene (Rockville, MD).

    Techniques: Transfection

    CCK-induced inward current is dependent on G proteins. A, Current response recorded from a cell transfected with CCK2 receptors and TRPC5 channels in the intracellular solution containing GDP-β-S (2 mM). B, Voltage-current relationship before

    Journal: European Journal of Pharmacology

    Article Title: Phospholipase C not protein kinase C is required for the activation of TRPC5 channels by cholecystokinin

    doi: 10.1016/j.ejphar.2012.05.032

    Figure Lengend Snippet: CCK-induced inward current is dependent on G proteins. A, Current response recorded from a cell transfected with CCK2 receptors and TRPC5 channels in the intracellular solution containing GDP-β-S (2 mM). B, Voltage-current relationship before

    Article Snippet: Briefly, a cDNA construct containing TRPC5 channels (GenBank accession number NM 012471) subcloned into pCMV6-XL4 was purchased from OriGene (Rockville, MD).

    Techniques: Transfection

    CCK increases the open probability of TRPC5 single channels. A 1 , Single channel currents recorded at different holding potentials in cell-attached patches. The pipette solution contained 0.3 μM CCK. A 2 , Plot of the amplitudes of single channel

    Journal: European Journal of Pharmacology

    Article Title: Phospholipase C not protein kinase C is required for the activation of TRPC5 channels by cholecystokinin

    doi: 10.1016/j.ejphar.2012.05.032

    Figure Lengend Snippet: CCK increases the open probability of TRPC5 single channels. A 1 , Single channel currents recorded at different holding potentials in cell-attached patches. The pipette solution contained 0.3 μM CCK. A 2 , Plot of the amplitudes of single channel

    Article Snippet: Briefly, a cDNA construct containing TRPC5 channels (GenBank accession number NM 012471) subcloned into pCMV6-XL4 was purchased from OriGene (Rockville, MD).

    Techniques: Transferring

    Insulin response requires TRPC channel activation and PI3 kinase (A–E) Representative traces of the insulin-induced currents in the presence of the TRPC channel blocker 2-APB (100 μM) (A) or TRPC5 channel enhancers La 3+ (100 μM) (B) and rosiglitazone (C and D) or PI3K inhibitor wortmannin (100 nM) (E). V hold = −60 mV. Similar to La 3+ , rosiglitazone (100 μM) potentiated insulin-activated inward currents. (F) Bar graphs summarizing the effects of Wort, 2-APB, and TRPC 4,5 channel enhancers La 3+ and rosiglitazone (100 μM) on the insulin-induced inward currents. La 3+ (100 μM) augmented the current by 5 fold and rosiglitazone (Rg) by about 2 fold. *** p

    Journal: Cell metabolism

    Article Title: Insulin Excites Anorexigenic Proopiomelanocortin Neurons via Activation of Canonical Transient Receptor Potential Channels

    doi: 10.1016/j.cmet.2014.03.004

    Figure Lengend Snippet: Insulin response requires TRPC channel activation and PI3 kinase (A–E) Representative traces of the insulin-induced currents in the presence of the TRPC channel blocker 2-APB (100 μM) (A) or TRPC5 channel enhancers La 3+ (100 μM) (B) and rosiglitazone (C and D) or PI3K inhibitor wortmannin (100 nM) (E). V hold = −60 mV. Similar to La 3+ , rosiglitazone (100 μM) potentiated insulin-activated inward currents. (F) Bar graphs summarizing the effects of Wort, 2-APB, and TRPC 4,5 channel enhancers La 3+ and rosiglitazone (100 μM) on the insulin-induced inward currents. La 3+ (100 μM) augmented the current by 5 fold and rosiglitazone (Rg) by about 2 fold. *** p

    Article Snippet: The TRPC5 channel activator rosiglitazone ( ) (Enzo Life Sciences, Inc., Farmingdale, NY) (100 mM) was dissolved in dimethylsulfoxide (DMSO).

    Techniques: Activation Assay