treatments rt 112 cells Search Results


  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 93
    CLS Cell Lines Service GmbH rt112 cells
    Rt112 Cells, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rt112 cells/product/CLS Cell Lines Service GmbH
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rt112 cells - by Bioz Stars, 2024-06
    93/100 stars
      Buy from Supplier

    88
    Rockland Immunochemicals rabbit anti rat red blood cell igg
    Rabbit Anti Rat Red Blood Cell Igg, supplied by Rockland Immunochemicals, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti rat red blood cell igg/product/Rockland Immunochemicals
    Average 88 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti rat red blood cell igg - by Bioz Stars, 2024-06
    88/100 stars
      Buy from Supplier

    86
    Thermo Fisher rt 112 cells
    (A, B) cell proliferation and (C) colony formation assay images for VM-CUB1 and <t>RT-112</t> cells treated with various concentrations of the PAK4 inhibitor.
    Rt 112 Cells, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rt 112 cells/product/Thermo Fisher
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rt 112 cells - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    86
    Millipore rt 112 cells
    (A) KG1a or (B) RT-4 cells were treated with INCB054828 for 2 hours, lysed and subjected to immunoblotting for phospho- and total proteins in the FGFR signal transduction pathway including FGFR, ERK, FRS2, and STAT5. (C) Concentration-dependent inhibition of phospho-FGFR3 by INCB054828 in <t>RT-112</t> cells was determined using a proximity ligation assay with a mouse monoclonal anti-phospho-FGFR (Y653/Y654) and rabbit anti-FGFR. Original Western blot images are shown in S1 File ( S1 Raw images).
    Rt 112 Cells, supplied by Millipore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rt 112 cells/product/Millipore
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rt 112 cells - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    86
    Beyotime rt 112 c6779 cell
    (A) KG1a or (B) RT-4 cells were treated with INCB054828 for 2 hours, lysed and subjected to immunoblotting for phospho- and total proteins in the FGFR signal transduction pathway including FGFR, ERK, FRS2, and STAT5. (C) Concentration-dependent inhibition of phospho-FGFR3 by INCB054828 in <t>RT-112</t> cells was determined using a proximity ligation assay with a mouse monoclonal anti-phospho-FGFR (Y653/Y654) and rabbit anti-FGFR. Original Western blot images are shown in S1 File ( S1 Raw images).
    Rt 112 C6779 Cell, supplied by Beyotime, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rt 112 c6779 cell/product/Beyotime
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rt 112 c6779 cell - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    Image Search Results


    (A, B) cell proliferation and (C) colony formation assay images for VM-CUB1 and RT-112 cells treated with various concentrations of the PAK4 inhibitor.

    Journal: bioRxiv

    Article Title: Therapeutically actionable PAK4 is amplified, overexpressed and involved in bladder cancer progression

    doi: 10.1101/740316

    Figure Lengend Snippet: (A, B) cell proliferation and (C) colony formation assay images for VM-CUB1 and RT-112 cells treated with various concentrations of the PAK4 inhibitor.

    Article Snippet: For si/miRNA transfections, VM-CUB1 and RT-112 cells were seeded at 1 × 10 5 cells per well in 6-well plates along with siRNA duplexes or miRNAs using Lipofectamine RNAiMAX Reagent (Life Technologies).

    Techniques: Colony Assay

    (A) KG1a or (B) RT-4 cells were treated with INCB054828 for 2 hours, lysed and subjected to immunoblotting for phospho- and total proteins in the FGFR signal transduction pathway including FGFR, ERK, FRS2, and STAT5. (C) Concentration-dependent inhibition of phospho-FGFR3 by INCB054828 in RT-112 cells was determined using a proximity ligation assay with a mouse monoclonal anti-phospho-FGFR (Y653/Y654) and rabbit anti-FGFR. Original Western blot images are shown in S1 File ( S1 Raw images).

    Journal: PLoS ONE

    Article Title: INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models

    doi: 10.1371/journal.pone.0231877

    Figure Lengend Snippet: (A) KG1a or (B) RT-4 cells were treated with INCB054828 for 2 hours, lysed and subjected to immunoblotting for phospho- and total proteins in the FGFR signal transduction pathway including FGFR, ERK, FRS2, and STAT5. (C) Concentration-dependent inhibition of phospho-FGFR3 by INCB054828 in RT-112 cells was determined using a proximity ligation assay with a mouse monoclonal anti-phospho-FGFR (Y653/Y654) and rabbit anti-FGFR. Original Western blot images are shown in S1 File ( S1 Raw images).

    Article Snippet: In situ phosphorylation of FGFR3 on RT-4 and RT-112 cells was performed using the Duolink PLA ® (Proximity Ligation Assay, Sigma Chemical, St. Louis, MO) with the following primary antibodies: rabbit anti-human FGFR3 (Abcam) and mouse anti-human pFGFR (Y653/654) (Cell Signaling) and the Duolink In Situ PLA ® Probe anti-rabbit PLUS and Duolink In Situ PLA ® Probe anti-mouse MINUS secondary probes.

    Techniques: Western Blot, Transduction, Concentration Assay, Inhibition, Proximity Ligation Assay

    (A) KATO III (FGFR2-amplified) gastric cancer model. Severe combined immunodeficiency mice bearing KATO III tumors were administered INCB054828 (0.03, 0.1, 0.3, or 1 mg/kg) or vehicle by gavage once daily for 10 days. The mean tumor size is plotted for each group of 8 mice. *** P < 0.001 vs vehicle. (B) KG1 ( FGFROP2-FGFR1 fusion positive) AML model. Humanized NSG mice bearing KG1 tumors were administered INCB054828 (0.3 mg/kg) or vehicle by gavage once daily for 14 days. The mean tumor size is plotted for each group of 6 mice. * P < 0.05 vs vehicle by paired t -test. (C) RT-112 ( FGFR3-TACC3 fusion positive) bladder carcinoma model. RNU immunocompromised rats bearing RT-112 tumors were administered INCB054828 (0.3 or 1 mg/kg) or vehicle by gavage once daily for 14 days. The mean tumor size is plotted for each group of 7 mice. ** P < 0.01 vs vehicle. (D) CTG-0997 ( FGFR2-TRA2B fusion positive) cholangiocarcinoma PDX model. Tumor bearing nu/nu mice were administered INCB054828 (0.3 or 1 mg/kg) or vehicle by gavage once daily for 42 days. The mean tumor size is plotted for each group of 12 mice. ** P < 0.01 vs vehicle. S.E.M., standard error of the mean.

    Journal: PLoS ONE

    Article Title: INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models

    doi: 10.1371/journal.pone.0231877

    Figure Lengend Snippet: (A) KATO III (FGFR2-amplified) gastric cancer model. Severe combined immunodeficiency mice bearing KATO III tumors were administered INCB054828 (0.03, 0.1, 0.3, or 1 mg/kg) or vehicle by gavage once daily for 10 days. The mean tumor size is plotted for each group of 8 mice. *** P < 0.001 vs vehicle. (B) KG1 ( FGFROP2-FGFR1 fusion positive) AML model. Humanized NSG mice bearing KG1 tumors were administered INCB054828 (0.3 mg/kg) or vehicle by gavage once daily for 14 days. The mean tumor size is plotted for each group of 6 mice. * P < 0.05 vs vehicle by paired t -test. (C) RT-112 ( FGFR3-TACC3 fusion positive) bladder carcinoma model. RNU immunocompromised rats bearing RT-112 tumors were administered INCB054828 (0.3 or 1 mg/kg) or vehicle by gavage once daily for 14 days. The mean tumor size is plotted for each group of 7 mice. ** P < 0.01 vs vehicle. (D) CTG-0997 ( FGFR2-TRA2B fusion positive) cholangiocarcinoma PDX model. Tumor bearing nu/nu mice were administered INCB054828 (0.3 or 1 mg/kg) or vehicle by gavage once daily for 42 days. The mean tumor size is plotted for each group of 12 mice. ** P < 0.01 vs vehicle. S.E.M., standard error of the mean.

    Article Snippet: In situ phosphorylation of FGFR3 on RT-4 and RT-112 cells was performed using the Duolink PLA ® (Proximity Ligation Assay, Sigma Chemical, St. Louis, MO) with the following primary antibodies: rabbit anti-human FGFR3 (Abcam) and mouse anti-human pFGFR (Y653/654) (Cell Signaling) and the Duolink In Situ PLA ® Probe anti-rabbit PLUS and Duolink In Situ PLA ® Probe anti-mouse MINUS secondary probes.

    Techniques: Amplification