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    Ipsen Group cognate snare syntaxin sx
    Cognate Snare Syntaxin Sx, supplied by Ipsen Group, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cognate snare syntaxin sx/product/Ipsen Group
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    cognate snare syntaxin sx - by Bioz Stars, 2021-05
    86/100 stars
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    86
    Ipsen Group target snare syntaxin sx
    Target Snare Syntaxin Sx, supplied by Ipsen Group, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/target snare syntaxin sx/product/Ipsen Group
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    target snare syntaxin sx - by Bioz Stars, 2021-05
    86/100 stars
      Buy from Supplier

    86
    Ipsen Group target syntaxin sx
    Specificity of <t>Munc18:Syntaxin</t> interactions. Munc18a (cyan) binds Sx1 (magenta) via two tight binding modes (left hand side). One binding mode occurs in the presence of the Sx1 N-peptide, the other in its absence. “Non-cognate” Munc18c (gray) also binds tightly to Sx1, though its interaction with Sx1 lacking the N-peptide is very weak (indicated by dotted line). Munc18c binds more tightly than Munc18a to Sx4 (orange) but neither Munc18 recognises Sx4 lacking its N-peptide. These findings indicate that Munc18a and Munc18c bind Sxs differently. Specifically Munc18a has two tight binding modes/sites for Sx1 one of which does not require the N-peptide binding interaction. Munc18c has one tight binding mode/site for Sx4 or Sx1 that requires the Sx N-peptide.
    Target Syntaxin Sx, supplied by Ipsen Group, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/target syntaxin sx/product/Ipsen Group
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    target syntaxin sx - by Bioz Stars, 2021-05
    86/100 stars
      Buy from Supplier

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    Specificity of Munc18:Syntaxin interactions. Munc18a (cyan) binds Sx1 (magenta) via two tight binding modes (left hand side). One binding mode occurs in the presence of the Sx1 N-peptide, the other in its absence. “Non-cognate” Munc18c (gray) also binds tightly to Sx1, though its interaction with Sx1 lacking the N-peptide is very weak (indicated by dotted line). Munc18c binds more tightly than Munc18a to Sx4 (orange) but neither Munc18 recognises Sx4 lacking its N-peptide. These findings indicate that Munc18a and Munc18c bind Sxs differently. Specifically Munc18a has two tight binding modes/sites for Sx1 one of which does not require the N-peptide binding interaction. Munc18c has one tight binding mode/site for Sx4 or Sx1 that requires the Sx N-peptide.

    Journal: PLoS ONE

    Article Title: Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins

    doi: 10.1371/journal.pone.0187302

    Figure Lengend Snippet: Specificity of Munc18:Syntaxin interactions. Munc18a (cyan) binds Sx1 (magenta) via two tight binding modes (left hand side). One binding mode occurs in the presence of the Sx1 N-peptide, the other in its absence. “Non-cognate” Munc18c (gray) also binds tightly to Sx1, though its interaction with Sx1 lacking the N-peptide is very weak (indicated by dotted line). Munc18c binds more tightly than Munc18a to Sx4 (orange) but neither Munc18 recognises Sx4 lacking its N-peptide. These findings indicate that Munc18a and Munc18c bind Sxs differently. Specifically Munc18a has two tight binding modes/sites for Sx1 one of which does not require the N-peptide binding interaction. Munc18c has one tight binding mode/site for Sx4 or Sx1 that requires the Sx N-peptide.

    Article Snippet: SM proteins are SNARE binding proteins that play a crucial role in the late stages of vesicle docking and fusion, as well as stabilisation of the target Syntaxin (Sx) proteins.

    Techniques: Binding Assay