Journal: PLoS Neglected Tropical Diseases
Article Title: Scabies-infested pregnant women: A critical therapeutic challenge
Figure Lengend Snippet: Hand of a scabies-infested pregnant woman with diffuse damaged skin. A 38-year-old Tunisian woman at 16 weeks of pregnancy presenting scabies as did her husband and their 2 children. Scabies was present for 4 months, and the skin was largely damaged with widespread eczematous on the limbs, trunk, breast, and nipples. Therapeutic management was challenging because topical scabicides were inconceivable, and oral ivermectin was unavailable in Tunisia. Oral ivermectin, 200 μg/kg body weight, repeated 1 week apart and brought back from the European market by the dermatologist, finally allowed for effective and safe treatment without any adverse pregnancy outcome. Collection of Prof . Mourad Mokni (MD , PhD) , Department of Dermatology , La Rabta Hospital , Tunis , Tunisia .
Article Snippet: These basic precautions mainly rely on experimental studies in mice showing adverse pregnancy outcomes (oral clefts and clubbed forepaws) at doses 10 to 100 times higher than current ivermectin human doses (150 to 200 μg/kg) ( https://www.merck.ca).