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  • 93
    Alomone Labs snx 482
    Effects of CTX alone and of a cocktail of toxins (CTX, ATX and SNX 482) on physostigmine (Physo)- and EFS (10 Hz)-induced contractions in isolated muscle strips of the guinea pig bladder. (A) Averaged data from six guinea pigs shows the lack of effect of CTX (0.3 µmol·L −1 ) on physostigmine (1 µmol·L −1 )-induced contractions in the presence of TTX (1 µmol·L −1 ). (B) Averaged data ( N = 7) of the effect of CTX (0.3 µmol·L −1 ) on EFS (10 Hz)-induced contractions. (C) Averaged data from five guinea pigs of the effects of the cocktail of toxins [CTX (0.3 µmol·L −1 ), ATX (0.1 µmol·L −1 ) and <t>SNX</t> 482 (0.3 µmol·L −1 )] on physostigmine (1 µmol·L −1 )-induced contractions, in the presence of TTX (1 µmol·L −1 ). (D) Averaged data ( N = 5) of the effect of the same cocktail of toxins on EFS (10 Hz)-induced contractions revealing significant, but incomplete blockade. (E) Averaged data ( N = 6) of the corresponding time control for the effect of 1 µmol·L −1 physostigmine (physo 1 = 25–30 min and physo 2 = 45–50 min) alone. *, significant difference from TTX, P
    Snx 482, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/snx 482/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    snx 482 - by Bioz Stars, 2022-05
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    86
    Peptides International snx 482
    Effects of CTX alone and of a cocktail of toxins (CTX, ATX and SNX 482) on physostigmine (Physo)- and EFS (10 Hz)-induced contractions in isolated muscle strips of the guinea pig bladder. (A) Averaged data from six guinea pigs shows the lack of effect of CTX (0.3 µmol·L −1 ) on physostigmine (1 µmol·L −1 )-induced contractions in the presence of TTX (1 µmol·L −1 ). (B) Averaged data ( N = 7) of the effect of CTX (0.3 µmol·L −1 ) on EFS (10 Hz)-induced contractions. (C) Averaged data from five guinea pigs of the effects of the cocktail of toxins [CTX (0.3 µmol·L −1 ), ATX (0.1 µmol·L −1 ) and <t>SNX</t> 482 (0.3 µmol·L −1 )] on physostigmine (1 µmol·L −1 )-induced contractions, in the presence of TTX (1 µmol·L −1 ). (D) Averaged data ( N = 5) of the effect of the same cocktail of toxins on EFS (10 Hz)-induced contractions revealing significant, but incomplete blockade. (E) Averaged data ( N = 6) of the corresponding time control for the effect of 1 µmol·L −1 physostigmine (physo 1 = 25–30 min and physo 2 = 45–50 min) alone. *, significant difference from TTX, P
    Snx 482, supplied by Peptides International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/snx 482/product/Peptides International
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    snx 482 - by Bioz Stars, 2022-05
    86/100 stars
      Buy from Supplier

    86
    Peptide Institute snx 482
    Contribution of P/Q-type channels to inhibitory synaptic transmission to FS-GABA neurons and no involvement of N- nor R-type channels in LTP. A , No remarkable effects of ω-conotoxin-GVIA (Ctx), a blocker for N-type channels, and <t>SNX-482,</t> a blocker
    Snx 482, supplied by Peptide Institute, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/snx 482/product/Peptide Institute
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    snx 482 - by Bioz Stars, 2022-05
    86/100 stars
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    92
    Tocris snx 482
    Contribution of P/Q-type channels to inhibitory synaptic transmission to FS-GABA neurons and no involvement of N- nor R-type channels in LTP. A , No remarkable effects of ω-conotoxin-GVIA (Ctx), a blocker for N-type channels, and <t>SNX-482,</t> a blocker
    Snx 482, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/snx 482/product/Tocris
    Average 92 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    snx 482 - by Bioz Stars, 2022-05
    92/100 stars
      Buy from Supplier

    Image Search Results


    Effects of CTX alone and of a cocktail of toxins (CTX, ATX and SNX 482) on physostigmine (Physo)- and EFS (10 Hz)-induced contractions in isolated muscle strips of the guinea pig bladder. (A) Averaged data from six guinea pigs shows the lack of effect of CTX (0.3 µmol·L −1 ) on physostigmine (1 µmol·L −1 )-induced contractions in the presence of TTX (1 µmol·L −1 ). (B) Averaged data ( N = 7) of the effect of CTX (0.3 µmol·L −1 ) on EFS (10 Hz)-induced contractions. (C) Averaged data from five guinea pigs of the effects of the cocktail of toxins [CTX (0.3 µmol·L −1 ), ATX (0.1 µmol·L −1 ) and SNX 482 (0.3 µmol·L −1 )] on physostigmine (1 µmol·L −1 )-induced contractions, in the presence of TTX (1 µmol·L −1 ). (D) Averaged data ( N = 5) of the effect of the same cocktail of toxins on EFS (10 Hz)-induced contractions revealing significant, but incomplete blockade. (E) Averaged data ( N = 6) of the corresponding time control for the effect of 1 µmol·L −1 physostigmine (physo 1 = 25–30 min and physo 2 = 45–50 min) alone. *, significant difference from TTX, P

    Journal: British Journal of Pharmacology

    Article Title: Spontaneous release of acetylcholine from autonomic nerves in the bladder

    doi: 10.1111/j.1476-5381.2009.00166.x

    Figure Lengend Snippet: Effects of CTX alone and of a cocktail of toxins (CTX, ATX and SNX 482) on physostigmine (Physo)- and EFS (10 Hz)-induced contractions in isolated muscle strips of the guinea pig bladder. (A) Averaged data from six guinea pigs shows the lack of effect of CTX (0.3 µmol·L −1 ) on physostigmine (1 µmol·L −1 )-induced contractions in the presence of TTX (1 µmol·L −1 ). (B) Averaged data ( N = 7) of the effect of CTX (0.3 µmol·L −1 ) on EFS (10 Hz)-induced contractions. (C) Averaged data from five guinea pigs of the effects of the cocktail of toxins [CTX (0.3 µmol·L −1 ), ATX (0.1 µmol·L −1 ) and SNX 482 (0.3 µmol·L −1 )] on physostigmine (1 µmol·L −1 )-induced contractions, in the presence of TTX (1 µmol·L −1 ). (D) Averaged data ( N = 5) of the effect of the same cocktail of toxins on EFS (10 Hz)-induced contractions revealing significant, but incomplete blockade. (E) Averaged data ( N = 6) of the corresponding time control for the effect of 1 µmol·L −1 physostigmine (physo 1 = 25–30 min and physo 2 = 45–50 min) alone. *, significant difference from TTX, P

    Article Snippet: In order to investigate which neuronal Ca2+ channel is responsible for spontaneous acetylcholine release, we studied the effects of selective Ca2+ channels blockers, such as CTX (for N type), ATX (for P/Q type) or by SNX 482 (for R-type).

    Techniques: Isolation

    Contribution of P/Q-type channels to inhibitory synaptic transmission to FS-GABA neurons and no involvement of N- nor R-type channels in LTP. A , No remarkable effects of ω-conotoxin-GVIA (Ctx), a blocker for N-type channels, and SNX-482, a blocker

    Journal: The Journal of Neuroscience

    Article Title: Cell Type-Specific, Presynaptic LTP of Inhibitory Synapses on Fast-Spiking GABAergic Neurons in the Mouse Visual Cortex

    doi: 10.1523/JNEUROSCI.1386-12.2012

    Figure Lengend Snippet: Contribution of P/Q-type channels to inhibitory synaptic transmission to FS-GABA neurons and no involvement of N- nor R-type channels in LTP. A , No remarkable effects of ω-conotoxin-GVIA (Ctx), a blocker for N-type channels, and SNX-482, a blocker

    Article Snippet: To confirm this suggestion, we tested a blocker for VGCCs of the R type, SNX-482, at 300 n m ( ; ) in seven FS-GABA neurons and found that this blocker did not significantly affect IPSPs in any of these neurons.

    Techniques: Transmission Assay