Journal: Scientific Reports
Article Title: Phenotypic, genotypic and antigenic characterization of emerging avian reoviruses isolated from clinical cases of arthritis in broilers in Saskatchewan, Canada
Figure Lengend Snippet: ( a ) A multiple amino acid sequence alignment of the common American vaccine strain S1133 and the 28 ARV field isolates. The alignment was made by a ClustalW alignment with BLOSUM cost matrix technique. Disagreements to the consensus sequence are highlighted. ( b ) Mapping of Dde I, Hinc II, Taq aI, Bcn I and Hae III restriction sites on Sigma C sequences of the ARV isolates (i.e. one isolate from each cluster group SK-R23 [Cluster II], SK-R16 [Cluster IV], SK-R10 [Cluster V], SK-R3 [Cluster VI]).
Article Snippet: Structure modelling and antigenicity prediction A blast search in PDB protein data bank using Sigma C protein sequences of our ARV isolates produced the S1133 Sigma C protein structure [PDB 2jjl] as the first hit and was chosen as a template structure.