r flurbiprofen Search Results


  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 92
    Cayman Chemical r flurbiprofen
    R Flurbiprofen, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/r flurbiprofen/product/Cayman Chemical
    Average 92 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    r flurbiprofen - by Bioz Stars, 2024-06
    92/100 stars
      Buy from Supplier

    86
    Santa Cruz Biotechnology r flurbiprofen
    Avermectins Increase the Aβ38/Aβ42 Ratio in Human TS21 Neurons, in a Manner Phenotypically Similar to Previously Identified γ-Secretase Modulators The γ-secretase modulators <t>(R)-flurbiprofen</t> (A) and E2012 (B) dose-dependently increase the ratio of Aβ38 to Aβ42 in human TS21 cortical neurons. The avermectins abamectin (C) and ivermectin (D), identified in the primary screen, as well as emamectin benzoate (E) and selamectin (F), also dose-dependently increase the Aβ38/Aβ42 ratio, while the structurally related milbemycin moxidectin (G) has no consistent effect. n = 3–6 cultures/concentration. Error bars represent SD. Note that abamectin, ivermectin, and emamectin benzoate are all mixtures of B1a (R = CH 2 CH 3 ) and B1b (R = CH 3 ) components.
    R Flurbiprofen, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/r flurbiprofen/product/Santa Cruz Biotechnology
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    r flurbiprofen - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    86
    Myriad Genetics r flurbiprofen
    Avermectins Increase the Aβ38/Aβ42 Ratio in Human TS21 Neurons, in a Manner Phenotypically Similar to Previously Identified γ-Secretase Modulators The γ-secretase modulators <t>(R)-flurbiprofen</t> (A) and E2012 (B) dose-dependently increase the ratio of Aβ38 to Aβ42 in human TS21 cortical neurons. The avermectins abamectin (C) and ivermectin (D), identified in the primary screen, as well as emamectin benzoate (E) and selamectin (F), also dose-dependently increase the Aβ38/Aβ42 ratio, while the structurally related milbemycin moxidectin (G) has no consistent effect. n = 3–6 cultures/concentration. Error bars represent SD. Note that abamectin, ivermectin, and emamectin benzoate are all mixtures of B1a (R = CH 2 CH 3 ) and B1b (R = CH 3 ) components.
    R Flurbiprofen, supplied by Myriad Genetics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/r flurbiprofen/product/Myriad Genetics
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    r flurbiprofen - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    86
    Millipore r flurbiprofen
    Avermectins Increase the Aβ38/Aβ42 Ratio in Human TS21 Neurons, in a Manner Phenotypically Similar to Previously Identified γ-Secretase Modulators The γ-secretase modulators <t>(R)-flurbiprofen</t> (A) and E2012 (B) dose-dependently increase the ratio of Aβ38 to Aβ42 in human TS21 cortical neurons. The avermectins abamectin (C) and ivermectin (D), identified in the primary screen, as well as emamectin benzoate (E) and selamectin (F), also dose-dependently increase the Aβ38/Aβ42 ratio, while the structurally related milbemycin moxidectin (G) has no consistent effect. n = 3–6 cultures/concentration. Error bars represent SD. Note that abamectin, ivermectin, and emamectin benzoate are all mixtures of B1a (R = CH 2 CH 3 ) and B1b (R = CH 3 ) components.
    R Flurbiprofen, supplied by Millipore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/r flurbiprofen/product/Millipore
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    r flurbiprofen - by Bioz Stars, 2024-06
    86/100 stars
      Buy from Supplier

    Image Search Results


    Avermectins Increase the Aβ38/Aβ42 Ratio in Human TS21 Neurons, in a Manner Phenotypically Similar to Previously Identified γ-Secretase Modulators The γ-secretase modulators (R)-flurbiprofen (A) and E2012 (B) dose-dependently increase the ratio of Aβ38 to Aβ42 in human TS21 cortical neurons. The avermectins abamectin (C) and ivermectin (D), identified in the primary screen, as well as emamectin benzoate (E) and selamectin (F), also dose-dependently increase the Aβ38/Aβ42 ratio, while the structurally related milbemycin moxidectin (G) has no consistent effect. n = 3–6 cultures/concentration. Error bars represent SD. Note that abamectin, ivermectin, and emamectin benzoate are all mixtures of B1a (R = CH 2 CH 3 ) and B1b (R = CH 3 ) components.

    Journal: Stem Cell Reports

    Article Title: Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer’s Disease

    doi: 10.1016/j.stemcr.2017.02.006

    Figure Lengend Snippet: Avermectins Increase the Aβ38/Aβ42 Ratio in Human TS21 Neurons, in a Manner Phenotypically Similar to Previously Identified γ-Secretase Modulators The γ-secretase modulators (R)-flurbiprofen (A) and E2012 (B) dose-dependently increase the ratio of Aβ38 to Aβ42 in human TS21 cortical neurons. The avermectins abamectin (C) and ivermectin (D), identified in the primary screen, as well as emamectin benzoate (E) and selamectin (F), also dose-dependently increase the Aβ38/Aβ42 ratio, while the structurally related milbemycin moxidectin (G) has no consistent effect. n = 3–6 cultures/concentration. Error bars represent SD. Note that abamectin, ivermectin, and emamectin benzoate are all mixtures of B1a (R = CH 2 CH 3 ) and B1b (R = CH 3 ) components.

    Article Snippet: Additional compounds used included (R)-flurbiprofen (Cayman), the γ-secretase modulator E2012 (ChemExpress), abamectin (Santa Cruz Biotechnology), ivermectin (Tocris Biosciences), emamectin benzoate (Abcam), selamectin (MicroSource Discovery Systems), moxidectin (Santa Cruz), strychnine HCl (Abcam), picrotoxin (Tocris), muscimol (Tocris), and the γ-secretase inhibitors DAPT (Sigma) and L-685,458 (Merck-Millipore).

    Techniques: Concentration Assay