purinergic receptor p2x 3 Search Results


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  • 86
    Millipore purinergic receptor p2x3
    BDNF overexpression protects <t>P2X3</t> labelling of taste buds and gustatory innervation. IHC with P2X3 antibodies showed preserved innervation inside the taste buds (d, thick arrow) and in the subepithelial nerve plexus of the circumvallate papillae of vismodegib‐treated GB759 (d, thin arrow) compared to vismodegib‐treated wild‐type mice (c). Both vismodegib‐treated (d) and vehicle‐treated (b) GB759 mice showed stronger labeling compared to their wild‐type controls (a,c) Because of the orientation of the section, the subepithelial nerve plexus is not visible in vehicle‐treated GB759mice (b). There was a significant decrease in P2X3 fluorescence intensity in vismodegib‐treated wild‐type mice (e), whereas there was no significant decrease in vismodegib‐treated GB759 mice. Scale bar = 50 µm. * p < 0.05; *** p < 0.001. IHC, immunohistochemistry
    Purinergic Receptor P2x3, supplied by Millipore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Takeda purinergic p2x3 receptor
    BDNF overexpression protects <t>P2X3</t> labelling of taste buds and gustatory innervation. IHC with P2X3 antibodies showed preserved innervation inside the taste buds (d, thick arrow) and in the subepithelial nerve plexus of the circumvallate papillae of vismodegib‐treated GB759 (d, thin arrow) compared to vismodegib‐treated wild‐type mice (c). Both vismodegib‐treated (d) and vehicle‐treated (b) GB759 mice showed stronger labeling compared to their wild‐type controls (a,c) Because of the orientation of the section, the subepithelial nerve plexus is not visible in vehicle‐treated GB759mice (b). There was a significant decrease in P2X3 fluorescence intensity in vismodegib‐treated wild‐type mice (e), whereas there was no significant decrease in vismodegib‐treated GB759 mice. Scale bar = 50 µm. * p < 0.05; *** p < 0.001. IHC, immunohistochemistry
    Purinergic P2x3 Receptor, supplied by Takeda, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Proteintech 194 anti p2rx3
    BDNF overexpression protects <t>P2X3</t> labelling of taste buds and gustatory innervation. IHC with P2X3 antibodies showed preserved innervation inside the taste buds (d, thick arrow) and in the subepithelial nerve plexus of the circumvallate papillae of vismodegib‐treated GB759 (d, thin arrow) compared to vismodegib‐treated wild‐type mice (c). Both vismodegib‐treated (d) and vehicle‐treated (b) GB759 mice showed stronger labeling compared to their wild‐type controls (a,c) Because of the orientation of the section, the subepithelial nerve plexus is not visible in vehicle‐treated GB759mice (b). There was a significant decrease in P2X3 fluorescence intensity in vismodegib‐treated wild‐type mice (e), whereas there was no significant decrease in vismodegib‐treated GB759 mice. Scale bar = 50 µm. * p < 0.05; *** p < 0.001. IHC, immunohistochemistry
    194 Anti P2rx3, supplied by Proteintech, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Merck & Co efficacy purinergic receptors p2x3 antagonists gefapixant
    BDNF overexpression protects <t>P2X3</t> labelling of taste buds and gustatory innervation. IHC with P2X3 antibodies showed preserved innervation inside the taste buds (d, thick arrow) and in the subepithelial nerve plexus of the circumvallate papillae of vismodegib‐treated GB759 (d, thin arrow) compared to vismodegib‐treated wild‐type mice (c). Both vismodegib‐treated (d) and vehicle‐treated (b) GB759 mice showed stronger labeling compared to their wild‐type controls (a,c) Because of the orientation of the section, the subepithelial nerve plexus is not visible in vehicle‐treated GB759mice (b). There was a significant decrease in P2X3 fluorescence intensity in vismodegib‐treated wild‐type mice (e), whereas there was no significant decrease in vismodegib‐treated GB759 mice. Scale bar = 50 µm. * p < 0.05; *** p < 0.001. IHC, immunohistochemistry
    Efficacy Purinergic Receptors P2x3 Antagonists Gefapixant, supplied by Merck & Co, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Millipore antibody against p2x3 purinergic receptor
    BDNF overexpression protects <t>P2X3</t> labelling of taste buds and gustatory innervation. IHC with P2X3 antibodies showed preserved innervation inside the taste buds (d, thick arrow) and in the subepithelial nerve plexus of the circumvallate papillae of vismodegib‐treated GB759 (d, thin arrow) compared to vismodegib‐treated wild‐type mice (c). Both vismodegib‐treated (d) and vehicle‐treated (b) GB759 mice showed stronger labeling compared to their wild‐type controls (a,c) Because of the orientation of the section, the subepithelial nerve plexus is not visible in vehicle‐treated GB759mice (b). There was a significant decrease in P2X3 fluorescence intensity in vismodegib‐treated wild‐type mice (e), whereas there was no significant decrease in vismodegib‐treated GB759 mice. Scale bar = 50 µm. * p < 0.05; *** p < 0.001. IHC, immunohistochemistry
    Antibody Against P2x3 Purinergic Receptor, supplied by Millipore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Image Search Results


    BDNF overexpression protects P2X3 labelling of taste buds and gustatory innervation. IHC with P2X3 antibodies showed preserved innervation inside the taste buds (d, thick arrow) and in the subepithelial nerve plexus of the circumvallate papillae of vismodegib‐treated GB759 (d, thin arrow) compared to vismodegib‐treated wild‐type mice (c). Both vismodegib‐treated (d) and vehicle‐treated (b) GB759 mice showed stronger labeling compared to their wild‐type controls (a,c) Because of the orientation of the section, the subepithelial nerve plexus is not visible in vehicle‐treated GB759mice (b). There was a significant decrease in P2X3 fluorescence intensity in vismodegib‐treated wild‐type mice (e), whereas there was no significant decrease in vismodegib‐treated GB759 mice. Scale bar = 50 µm. * p < 0.05; *** p < 0.001. IHC, immunohistochemistry

    Journal: The European Journal of Neuroscience

    Article Title: Brain‐derived neurotrophic factor overexpression in taste buds diminishes chemotherapy induced taste loss

    doi: 10.1111/ejn.15799

    Figure Lengend Snippet: BDNF overexpression protects P2X3 labelling of taste buds and gustatory innervation. IHC with P2X3 antibodies showed preserved innervation inside the taste buds (d, thick arrow) and in the subepithelial nerve plexus of the circumvallate papillae of vismodegib‐treated GB759 (d, thin arrow) compared to vismodegib‐treated wild‐type mice (c). Both vismodegib‐treated (d) and vehicle‐treated (b) GB759 mice showed stronger labeling compared to their wild‐type controls (a,c) Because of the orientation of the section, the subepithelial nerve plexus is not visible in vehicle‐treated GB759mice (b). There was a significant decrease in P2X3 fluorescence intensity in vismodegib‐treated wild‐type mice (e), whereas there was no significant decrease in vismodegib‐treated GB759 mice. Scale bar = 50 µm. * p < 0.05; *** p < 0.001. IHC, immunohistochemistry

    Article Snippet: Immunohistochemical detection of Sonic Hedgehog (Shh, rabbit, Santa Cruz, 1:100), Ki67 (rat, eBioscience, 1:100), Taste 1 receptor member 3 (T1R3, goat, Santa Cruz Biotechnology, 1:500), α‐Gustducin (rabbit, Santa‐Cruz, 1:200), Troma‐1 (rat, Hybridoma bank, 1:80), neural cell adhesion molecule (NCAM, rabbit, Chemicon, 1:400) and purinergic receptor P2X3 (P2X3, guinea pig, Chemicon, 1:500) was performed on paraformaldehyde pre‐fixed sections and incubated overnight at 4°C if nothing else was noted.

    Techniques: Over Expression, Labeling, Fluorescence, Immunohistochemistry