og–l002 Search Results


og l002  (Tocris)
90
Tocris og l002
Og L002, supplied by Tocris, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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og l002  (MedChemExpress)
91
MedChemExpress og l002
Og L002, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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og l002  (Selleck Chemicals)
94
Selleck Chemicals og l002
Og L002, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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og–l002  (ApexBio)
90
ApexBio og–l002
Og–L002, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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og-l002 (m60161-2s)  (Xcessbio Inc)
90
Xcessbio Inc og-l002 (m60161-2s)
Og L002 (M60161 2s), supplied by Xcessbio Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/og-l002 (m60161-2s)/product/Xcessbio Inc
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og-l002 20 mg/kg  (Charles River Laboratories)
90
Charles River Laboratories og-l002 20 mg/kg
LSD1 regulates MuSCs self-renewal potential. ( A ) PAX7 and MyHC staining and percentage of PAX7+ cells after 48 h under myogenic differentiation conditions of CTRL SC and LSD1 SCiKO MuSCs. ( B ) PAX7 and MyHC staining and percentage of PAX7+ cells after 48 h under myogenic differentiation conditions of MuSCs treated with LSD1 inhibitors <t>(OG-L002</t> and Pargyline). ( C ) Bodipy, PAX7, desmin and Oil Red O staining of cells after 48 h under myogenic differentiation conditions of CTRL SC and LSD1 SCiKO MuSCs. ( D ) CTX experimental setup. ( E ) Anti-Laminin staining on cryosections of regenerated TA muscles in CTRL SC and LSD1 SCiKO mice at 28 dpi. Quantification of the number of myofibers per mm2. ( F ) CSA distribution of muscle fibers in CTRL SC and LSD1 SCiKO mice TA cryosections at 28 dpi. ( G ) Anti-PAX7 and anti-Laminin staining on cryosections of regenerated TA muscles in CTRL SC and LSD1 SCiKO mice at 28 dpi. Quantification of the number of sublaminar PAX7+/Ki67- cells per mm2. ( H ) CTX experimental setup. ( I ) Anti-PAX7 and anti-Laminin staining on cryosections of regenerated TA muscles in Vehicle and OG-L002 treated mice at 21 dpi. Quantification of the number of sublaminar PAX7+/Ki67− cells per mm 2 . ( J ) H&E and Oil Red O staining on cryosections of regenerated TA muscles in Vehicle and OG-L002 treated mice at 21 dpi. ( K ) Anti-Laminin staining on cryosections of regenerated TA muscles in Vehicle and OG-L002 treated mice at 21 dpi. Quantification of the number of myofibers per mm 2 . Scale bars, 50 μm. n = 3 mice/genotype. n = 3 primary MuSC cultures/genotype. n = 3 primary MuSC cultures/treatments. Values are mean or percentage mean ± SEM. ** P < 0.01 (Mann–Whitney–Wilcoxon test) *** P < 0.001 (Bonferroni test after one way-ANOVA).
Og L002 20 Mg/Kg, supplied by Charles River Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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og-l002 20 mg/kg - by Bioz Stars, 2026-02
90/100 stars
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Image Search Results


LSD1 regulates MuSCs self-renewal potential. ( A ) PAX7 and MyHC staining and percentage of PAX7+ cells after 48 h under myogenic differentiation conditions of CTRL SC and LSD1 SCiKO MuSCs. ( B ) PAX7 and MyHC staining and percentage of PAX7+ cells after 48 h under myogenic differentiation conditions of MuSCs treated with LSD1 inhibitors (OG-L002 and Pargyline). ( C ) Bodipy, PAX7, desmin and Oil Red O staining of cells after 48 h under myogenic differentiation conditions of CTRL SC and LSD1 SCiKO MuSCs. ( D ) CTX experimental setup. ( E ) Anti-Laminin staining on cryosections of regenerated TA muscles in CTRL SC and LSD1 SCiKO mice at 28 dpi. Quantification of the number of myofibers per mm2. ( F ) CSA distribution of muscle fibers in CTRL SC and LSD1 SCiKO mice TA cryosections at 28 dpi. ( G ) Anti-PAX7 and anti-Laminin staining on cryosections of regenerated TA muscles in CTRL SC and LSD1 SCiKO mice at 28 dpi. Quantification of the number of sublaminar PAX7+/Ki67- cells per mm2. ( H ) CTX experimental setup. ( I ) Anti-PAX7 and anti-Laminin staining on cryosections of regenerated TA muscles in Vehicle and OG-L002 treated mice at 21 dpi. Quantification of the number of sublaminar PAX7+/Ki67− cells per mm 2 . ( J ) H&E and Oil Red O staining on cryosections of regenerated TA muscles in Vehicle and OG-L002 treated mice at 21 dpi. ( K ) Anti-Laminin staining on cryosections of regenerated TA muscles in Vehicle and OG-L002 treated mice at 21 dpi. Quantification of the number of myofibers per mm 2 . Scale bars, 50 μm. n = 3 mice/genotype. n = 3 primary MuSC cultures/genotype. n = 3 primary MuSC cultures/treatments. Values are mean or percentage mean ± SEM. ** P < 0.01 (Mann–Whitney–Wilcoxon test) *** P < 0.001 (Bonferroni test after one way-ANOVA).

Journal: Nucleic Acids Research

Article Title: LSD1 controls a nuclear checkpoint in Wnt/β-Catenin signaling to regulate muscle stem cell self-renewal

doi: 10.1093/nar/gkae060

Figure Lengend Snippet: LSD1 regulates MuSCs self-renewal potential. ( A ) PAX7 and MyHC staining and percentage of PAX7+ cells after 48 h under myogenic differentiation conditions of CTRL SC and LSD1 SCiKO MuSCs. ( B ) PAX7 and MyHC staining and percentage of PAX7+ cells after 48 h under myogenic differentiation conditions of MuSCs treated with LSD1 inhibitors (OG-L002 and Pargyline). ( C ) Bodipy, PAX7, desmin and Oil Red O staining of cells after 48 h under myogenic differentiation conditions of CTRL SC and LSD1 SCiKO MuSCs. ( D ) CTX experimental setup. ( E ) Anti-Laminin staining on cryosections of regenerated TA muscles in CTRL SC and LSD1 SCiKO mice at 28 dpi. Quantification of the number of myofibers per mm2. ( F ) CSA distribution of muscle fibers in CTRL SC and LSD1 SCiKO mice TA cryosections at 28 dpi. ( G ) Anti-PAX7 and anti-Laminin staining on cryosections of regenerated TA muscles in CTRL SC and LSD1 SCiKO mice at 28 dpi. Quantification of the number of sublaminar PAX7+/Ki67- cells per mm2. ( H ) CTX experimental setup. ( I ) Anti-PAX7 and anti-Laminin staining on cryosections of regenerated TA muscles in Vehicle and OG-L002 treated mice at 21 dpi. Quantification of the number of sublaminar PAX7+/Ki67− cells per mm 2 . ( J ) H&E and Oil Red O staining on cryosections of regenerated TA muscles in Vehicle and OG-L002 treated mice at 21 dpi. ( K ) Anti-Laminin staining on cryosections of regenerated TA muscles in Vehicle and OG-L002 treated mice at 21 dpi. Quantification of the number of myofibers per mm 2 . Scale bars, 50 μm. n = 3 mice/genotype. n = 3 primary MuSC cultures/genotype. n = 3 primary MuSC cultures/treatments. Values are mean or percentage mean ± SEM. ** P < 0.01 (Mann–Whitney–Wilcoxon test) *** P < 0.001 (Bonferroni test after one way-ANOVA).

Article Snippet: Nine-week-old C57BL/6J mice were purchased from Charles River laboratories and intraperitoneal injected with OG-L002 20 mg/kg or NaCl 0,9% for 7 days.

Techniques: Staining, Muscles, MANN-WHITNEY