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    Bruker Corporation maldi biotyper
    Bruker <t>MALDI</t> <t>Biotyper</t> System.
    Maldi Biotyper, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 99/100, based on 897 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/maldi biotyper/product/Bruker Corporation
    Average 99 stars, based on 897 article reviews
    Price from $9.99 to $1999.99
    maldi biotyper - by Bioz Stars, 2020-05
    99/100 stars
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    Bruker MALDI Biotyper System.

    Journal: Medical Journal, Armed Forces India

    Article Title: Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) for rapid identification of Mycobacterium abscessus

    doi: 10.1016/j.mjafi.2017.02.006

    Figure Lengend Snippet: Bruker MALDI Biotyper System.

    Article Snippet: Bruker Daltronics for the use of the MALDI Biotyper at the Bruker Center of Excellence, Bangalore.

    Techniques:

    A typical BoNT/A positive control from the Bruker MALDI Biotyper has an intact peptide substrate at 2406 m / z and two peptide fragments at 998 and 1426 m / z ( 1A ); One patient exhibited negative BoNT/A in serum ( 1B , 14-17944-01); however, a low concentration of BoNT/A was detected by MS in stool from the same patient ( 1C , 14-17944-02), whereas the mouse bioassay was negative for both specimen types. The patient specimen results were later confirmed when the contaminated food the patient ingested was positive for BoNT/A by MS ( 1D , 14-18209) and the mouse bioassay.

    Journal: Toxins

    Article Title: Implementing the Bruker MALDI Biotyper in the Public Health Laboratory for C. botulinum Neurotoxin Detection

    doi: 10.3390/toxins9030094

    Figure Lengend Snippet: A typical BoNT/A positive control from the Bruker MALDI Biotyper has an intact peptide substrate at 2406 m / z and two peptide fragments at 998 and 1426 m / z ( 1A ); One patient exhibited negative BoNT/A in serum ( 1B , 14-17944-01); however, a low concentration of BoNT/A was detected by MS in stool from the same patient ( 1C , 14-17944-02), whereas the mouse bioassay was negative for both specimen types. The patient specimen results were later confirmed when the contaminated food the patient ingested was positive for BoNT/A by MS ( 1D , 14-18209) and the mouse bioassay.

    Article Snippet: For the first time, a direct comparison with the MBA was performed to determine MS-based assay sensitivity using the Bruker MALDI Biotyper.

    Techniques: Positive Control, Concentration Assay, Mass Spectrometry

    Culture collections and methods used in this study for capsule typing of Haemophilus influenzae by MALDI-TOF mass spectrometry. An evaluation set of H. influenzae isolates of all capsule types from diverse geographic origins and time periods and isogenic capsule transformants ( 30 ) were used to investigate capsule type-specific differences in MALDI-TOF mass spectra. MLST was used to ensure adequate coverage of different genetic lineages of encapsulated H. influenzae . Reference isolates from the evaluation set (encapsulated and nonencapsulated) were selected to construct a new typing database in MALDI Biotyper. This database was tested with the remaining isolates in the set, and misclassified isolates were added to the database. The final supplemented database was blindly validated with a second culture collection that consisted of clinical invasive isolates. Hia, H. influenzae type a; Hib, H. influenzae type b; Hic, H. influenzae type c; Hid, H. influenzae type d; Hie, H. influenzae type e; Hif, H. influenzae type f; MALDI-TOF, matrix-assisted laser desorption/ionization time-of-flight; MLST, multilocus sequence typing; NTHi, nontypeable H. influenzae.

    Journal: Emerging Infectious Diseases

    Article Title: Capsule Typing of Haemophilus influenzae by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry 1

    doi: 10.3201/eid2403.170459

    Figure Lengend Snippet: Culture collections and methods used in this study for capsule typing of Haemophilus influenzae by MALDI-TOF mass spectrometry. An evaluation set of H. influenzae isolates of all capsule types from diverse geographic origins and time periods and isogenic capsule transformants ( 30 ) were used to investigate capsule type-specific differences in MALDI-TOF mass spectra. MLST was used to ensure adequate coverage of different genetic lineages of encapsulated H. influenzae . Reference isolates from the evaluation set (encapsulated and nonencapsulated) were selected to construct a new typing database in MALDI Biotyper. This database was tested with the remaining isolates in the set, and misclassified isolates were added to the database. The final supplemented database was blindly validated with a second culture collection that consisted of clinical invasive isolates. Hia, H. influenzae type a; Hib, H. influenzae type b; Hic, H. influenzae type c; Hid, H. influenzae type d; Hie, H. influenzae type e; Hif, H. influenzae type f; MALDI-TOF, matrix-assisted laser desorption/ionization time-of-flight; MLST, multilocus sequence typing; NTHi, nontypeable H. influenzae.

    Article Snippet: Construction and Validation of a MALDI Biotyper Database for Capsule Typing We used selected isolates from the evaluation set to create main spectra (MSPs) for a new MALDI Biotyper 4.1 database (Bruker Daltonics) ( ).

    Techniques: Mass Spectrometry, Construct, Hydrophobic Interaction Chromatography, Sequencing

    Retrospective study. (i) MALDI Biotyper identification rates of Gram-positive rods (GPR) are increased by formic acid treatment.

    Journal: Journal of Clinical Microbiology

    Article Title: Evaluation of the Bruker MALDI Biotyper for Identification of Gram-Positive Rods: Development of a Diagnostic Algorithm for the Clinical Laboratory

    doi: 10.1128/JCM.02399-13

    Figure Lengend Snippet: Retrospective study. (i) MALDI Biotyper identification rates of Gram-positive rods (GPR) are increased by formic acid treatment.

    Article Snippet: We have analyzed the performance of the Bruker MALDI Biotyper system for the identification of GPR and evaluated possible ways to improve its performance, i.e., different sample preparation methods, data interpretation algorithms (particularly the variation of score cutoff values), and extension of the database by proprietary reference entries.

    Techniques:

    Class dendrogram of all Enterobacter isolates built by the MALDI-TOF Biotyper 3.1 software. Asterisks ( ∗ ) identify strains isolated in general surgery and geriatric wards; the symbol § identify multidrug-resistant (MDR) strains.

    Journal: Frontiers in Microbiology

    Article Title: MALDI-TOF MS Identification and Clustering Applied to Enterobacter Species in Nosocomial Setting

    doi: 10.3389/fmicb.2018.01885

    Figure Lengend Snippet: Class dendrogram of all Enterobacter isolates built by the MALDI-TOF Biotyper 3.1 software. Asterisks ( ∗ ) identify strains isolated in general surgery and geriatric wards; the symbol § identify multidrug-resistant (MDR) strains.

    Article Snippet: Bacterial colonies were grown overnight on sheep blood agar and subjected to according to the MALDI Biotyper protocol (Bruker Daltonics GmbH, Bremen, Germany).

    Techniques: Software, Isolation