Journal: The Journal of Biological Chemistry
Article Title: Reductions in the Cardiac Transient Outward K+ Current Ito Caused by Chronic β-Adrenergic Receptor Stimulation Are Partly Rescued by Inhibition of Nuclear Factor κB *
Figure Lengend Snippet: NF-κB inhibition partly reverses decreases in I to,f caused by chronic β-AR stimulation. IkBαSA (adenovirally infected) was used to inhibit NF-κB signaling. A , representative current I to,f current traces. B , averaged I to,f current densities at +60 mV for GFP, GFP+ISO, IkBαSA and IkBαSA+ISO. C , relative mRNA expression for KChIP2, Kv4.3 and Kv4.2. For KChIP2, there is a positive interaction ( p
Article Snippet: For GAPDH detection, blots for Kv4.2 and KChIP2 were first stripped using commercial stripping buffer (ST010, GeBa) according to manufacturer's instructions.
Techniques: Inhibition, Infection, Expressing