exome library Search Results


  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 89
    Agilent technologies exome enriched libraries
    Representative results of the analysis conducted using the in-house designed <t>MTTE</t> assay A. The electropherograms of the MLPA results obtained in the analysis of specimens from distinct steps of the <t>exome-enriched</t> library preparation, performed using the leukemia_1 sample. The probe IDs are shown under the electropherograms. Asterisks indicate background signals (unspecific peaks). B. The bar plots (corresponding to the electropherograms shown in panel A) representing the relative enrichment (y-axis) of each analyzed region (x-axis). The corresponding RC as well as FE and OC values are indicated on the graphs (steps iv-v).
    Exome Enriched Libraries, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 89/100, based on 124 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/exome enriched libraries/product/Agilent technologies
    Average 89 stars, based on 124 article reviews
    Price from $9.99 to $1999.99
    exome enriched libraries - by Bioz Stars, 2020-07
    89/100 stars
      Buy from Supplier

    89
    Roche ez exome library
    Representative results of the analysis conducted using the in-house designed <t>MTTE</t> assay A. The electropherograms of the MLPA results obtained in the analysis of specimens from distinct steps of the <t>exome-enriched</t> library preparation, performed using the leukemia_1 sample. The probe IDs are shown under the electropherograms. Asterisks indicate background signals (unspecific peaks). B. The bar plots (corresponding to the electropherograms shown in panel A) representing the relative enrichment (y-axis) of each analyzed region (x-axis). The corresponding RC as well as FE and OC values are indicated on the graphs (steps iv-v).
    Ez Exome Library, supplied by Roche, used in various techniques. Bioz Stars score: 89/100, based on 16 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ez exome library/product/Roche
    Average 89 stars, based on 16 article reviews
    Price from $9.99 to $1999.99
    ez exome library - by Bioz Stars, 2020-07
    89/100 stars
      Buy from Supplier

    99
    Illumina Inc exome library kit
    Representative results of the analysis conducted using the in-house designed <t>MTTE</t> assay A. The electropherograms of the MLPA results obtained in the analysis of specimens from distinct steps of the <t>exome-enriched</t> library preparation, performed using the leukemia_1 sample. The probe IDs are shown under the electropherograms. Asterisks indicate background signals (unspecific peaks). B. The bar plots (corresponding to the electropherograms shown in panel A) representing the relative enrichment (y-axis) of each analyzed region (x-axis). The corresponding RC as well as FE and OC values are indicated on the graphs (steps iv-v).
    Exome Library Kit, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 99/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/exome library kit/product/Illumina Inc
    Average 99 stars, based on 6 article reviews
    Price from $9.99 to $1999.99
    exome library kit - by Bioz Stars, 2020-07
    99/100 stars
      Buy from Supplier

    99
    Illumina Inc exome library preparation
    Representative results of the analysis conducted using the in-house designed <t>MTTE</t> assay A. The electropherograms of the MLPA results obtained in the analysis of specimens from distinct steps of the <t>exome-enriched</t> library preparation, performed using the leukemia_1 sample. The probe IDs are shown under the electropherograms. Asterisks indicate background signals (unspecific peaks). B. The bar plots (corresponding to the electropherograms shown in panel A) representing the relative enrichment (y-axis) of each analyzed region (x-axis). The corresponding RC as well as FE and OC values are indicated on the graphs (steps iv-v).
    Exome Library Preparation, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 99/100, based on 24 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/exome library preparation/product/Illumina Inc
    Average 99 stars, based on 24 article reviews
    Price from $9.99 to $1999.99
    exome library preparation - by Bioz Stars, 2020-07
    99/100 stars
      Buy from Supplier

    90
    Illumina Inc truseq exome library prep kit
    Representative results of the analysis conducted using the in-house designed <t>MTTE</t> assay A. The electropherograms of the MLPA results obtained in the analysis of specimens from distinct steps of the <t>exome-enriched</t> library preparation, performed using the leukemia_1 sample. The probe IDs are shown under the electropherograms. Asterisks indicate background signals (unspecific peaks). B. The bar plots (corresponding to the electropherograms shown in panel A) representing the relative enrichment (y-axis) of each analyzed region (x-axis). The corresponding RC as well as FE and OC values are indicated on the graphs (steps iv-v).
    Truseq Exome Library Prep Kit, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 90/100, based on 50 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/truseq exome library prep kit/product/Illumina Inc
    Average 90 stars, based on 50 article reviews
    Price from $9.99 to $1999.99
    truseq exome library prep kit - by Bioz Stars, 2020-07
    90/100 stars
      Buy from Supplier

    95
    Illumina Inc nextera rapid exome library prep kit
    Representative results of the analysis conducted using the in-house designed <t>MTTE</t> assay A. The electropherograms of the MLPA results obtained in the analysis of specimens from distinct steps of the <t>exome-enriched</t> library preparation, performed using the leukemia_1 sample. The probe IDs are shown under the electropherograms. Asterisks indicate background signals (unspecific peaks). B. The bar plots (corresponding to the electropherograms shown in panel A) representing the relative enrichment (y-axis) of each analyzed region (x-axis). The corresponding RC as well as FE and OC values are indicated on the graphs (steps iv-v).
    Nextera Rapid Exome Library Prep Kit, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 95/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nextera rapid exome library prep kit/product/Illumina Inc
    Average 95 stars, based on 2 article reviews
    Price from $9.99 to $1999.99
    nextera rapid exome library prep kit - by Bioz Stars, 2020-07
    95/100 stars
      Buy from Supplier

    90
    Illumina Inc exome library
    Profiling off-target Cascade binding in a human <t>exome</t> (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a <t>MiSeq</t> chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).
    Exome Library, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 90/100, based on 191 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/exome library/product/Illumina Inc
    Average 90 stars, based on 191 article reviews
    Price from $9.99 to $1999.99
    exome library - by Bioz Stars, 2020-07
    90/100 stars
      Buy from Supplier

    90
    Roche nimblegen seqcap ez exome library
    Profiling off-target Cascade binding in a human <t>exome</t> (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a <t>MiSeq</t> chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).
    Nimblegen Seqcap Ez Exome Library, supplied by Roche, used in various techniques. Bioz Stars score: 90/100, based on 11 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nimblegen seqcap ez exome library/product/Roche
    Average 90 stars, based on 11 article reviews
    Price from $9.99 to $1999.99
    nimblegen seqcap ez exome library - by Bioz Stars, 2020-07
    90/100 stars
      Buy from Supplier

    93
    Agilent technologies sureselect exome v6 capture library
    Profiling off-target Cascade binding in a human <t>exome</t> (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a <t>MiSeq</t> chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).
    Sureselect Exome V6 Capture Library, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/sureselect exome v6 capture library/product/Agilent technologies
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    sureselect exome v6 capture library - by Bioz Stars, 2020-07
    93/100 stars
      Buy from Supplier

    89
    Illumina Inc exome sequencing libraries
    Profiling off-target Cascade binding in a human <t>exome</t> (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a <t>MiSeq</t> chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).
    Exome Sequencing Libraries, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 89/100, based on 65 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/exome sequencing libraries/product/Illumina Inc
    Average 89 stars, based on 65 article reviews
    Price from $9.99 to $1999.99
    exome sequencing libraries - by Bioz Stars, 2020-07
    89/100 stars
      Buy from Supplier

    92
    Clinical Genomics Centre Mount Sinai Hospital exome libraries
    Profiling off-target Cascade binding in a human <t>exome</t> (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a <t>MiSeq</t> chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).
    Exome Libraries, supplied by Clinical Genomics Centre Mount Sinai Hospital, used in various techniques. Bioz Stars score: 92/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/exome libraries/product/Clinical Genomics Centre Mount Sinai Hospital
    Average 92 stars, based on 2 article reviews
    Price from $9.99 to $1999.99
    exome libraries - by Bioz Stars, 2020-07
    92/100 stars
      Buy from Supplier

    85
    Roche seqcap ez exome libraries v3
    Profiling off-target Cascade binding in a human <t>exome</t> (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a <t>MiSeq</t> chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).
    Seqcap Ez Exome Libraries V3, supplied by Roche, used in various techniques. Bioz Stars score: 85/100, based on 21 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/seqcap ez exome libraries v3/product/Roche
    Average 85 stars, based on 21 article reviews
    Price from $9.99 to $1999.99
    seqcap ez exome libraries v3 - by Bioz Stars, 2020-07
    85/100 stars
      Buy from Supplier

    94
    Roche seqcap ez exome library kits
    Profiling off-target Cascade binding in a human <t>exome</t> (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a <t>MiSeq</t> chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).
    Seqcap Ez Exome Library Kits, supplied by Roche, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/seqcap ez exome library kits/product/Roche
    Average 94 stars, based on 5 article reviews
    Price from $9.99 to $1999.99
    seqcap ez exome library kits - by Bioz Stars, 2020-07
    94/100 stars
      Buy from Supplier

    99
    Illumina Inc truseq exome enriched libraries
    Profiling off-target Cascade binding in a human <t>exome</t> (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a <t>MiSeq</t> chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).
    Truseq Exome Enriched Libraries, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/truseq exome enriched libraries/product/Illumina Inc
    Average 99 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    truseq exome enriched libraries - by Bioz Stars, 2020-07
    99/100 stars
      Buy from Supplier

    89
    Roche seqcap ez human exome library
    Profiling off-target Cascade binding in a human <t>exome</t> (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a <t>MiSeq</t> chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).
    Seqcap Ez Human Exome Library, supplied by Roche, used in various techniques. Bioz Stars score: 89/100, based on 85 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/seqcap ez human exome library/product/Roche
    Average 89 stars, based on 85 article reviews
    Price from $9.99 to $1999.99
    seqcap ez human exome library - by Bioz Stars, 2020-07
    89/100 stars
      Buy from Supplier

    88
    Illumina Inc adamts17 exome libraries
    Profiling off-target Cascade binding in a human <t>exome</t> (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a <t>MiSeq</t> chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).
    Adamts17 Exome Libraries, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 88/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/adamts17 exome libraries/product/Illumina Inc
    Average 88 stars, based on 5 article reviews
    Price from $9.99 to $1999.99
    adamts17 exome libraries - by Bioz Stars, 2020-07
    88/100 stars
      Buy from Supplier

    88
    Agilent technologies exome library preparation
    Profiling off-target Cascade binding in a human <t>exome</t> (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a <t>MiSeq</t> chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).
    Exome Library Preparation, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 88/100, based on 20 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/exome library preparation/product/Agilent technologies
    Average 88 stars, based on 20 article reviews
    Price from $9.99 to $1999.99
    exome library preparation - by Bioz Stars, 2020-07
    88/100 stars
      Buy from Supplier

    Image Search Results


    Representative results of the analysis conducted using the in-house designed MTTE assay A. The electropherograms of the MLPA results obtained in the analysis of specimens from distinct steps of the exome-enriched library preparation, performed using the leukemia_1 sample. The probe IDs are shown under the electropherograms. Asterisks indicate background signals (unspecific peaks). B. The bar plots (corresponding to the electropherograms shown in panel A) representing the relative enrichment (y-axis) of each analyzed region (x-axis). The corresponding RC as well as FE and OC values are indicated on the graphs (steps iv-v).

    Journal: Oncotarget

    Article Title: MTTE: an innovative strategy for the evaluation of targeted/exome enrichment efficiency

    doi: 10.18632/oncotarget.11646

    Figure Lengend Snippet: Representative results of the analysis conducted using the in-house designed MTTE assay A. The electropherograms of the MLPA results obtained in the analysis of specimens from distinct steps of the exome-enriched library preparation, performed using the leukemia_1 sample. The probe IDs are shown under the electropherograms. Asterisks indicate background signals (unspecific peaks). B. The bar plots (corresponding to the electropherograms shown in panel A) representing the relative enrichment (y-axis) of each analyzed region (x-axis). The corresponding RC as well as FE and OC values are indicated on the graphs (steps iv-v).

    Article Snippet: Samples for the MTTE analysis were obtained at several steps during the preparation of exome-enriched libraries.

    Techniques: Multiplex Ligation-dependent Probe Amplification

    Variant calling comparison between Ion PGM data and both WES systems. Variant calling comparison between Ion PGM data (blue) and both Agilent SureSelect (green) and Roche NimbleGen (red) data in exon regions shows 88 % of concordance (44/50) in both WES capture systems ( a ). Both systems failed to call 4 genetic variants (*) detected by Ion PGM platform at low frequencies (4-16 %). Further 4 variants were missed as follows: 2 by Agilent (COSM6225, rs80338963) and 2 by Roche NimbleGen (COSM40942, rs35775721). Horizontal axis reports the genetic variants (Additional file 3 : Table S8a) ordered from lowest to highest frequency (vertical axis) as assessed by Ion PGM platform. Variant coverage displays a quite similar trend between Agilent (green) and Roche NimbleGen (red) libraries, and is far lower than Ion PGM platform (blue) ( b ). Two Roche libraries report a low coverage in the uncalled variants (COSM40942, rs35775721). Vertical axis displays the variant coverage in logarithmic scale. Variant calling comparison between Ion PGM data (blue) and both Agilent (green) and Roche NimbleGen (red) data in non-exon regions shows a poor performance of both WES technologies ( c ). Both WES systems failed to call the rs839541 (*) SNP in ERBB4 gene, whereas rs1558544 SNP in EGFR was missed by all 10 Agilent libraries. Vertical axis reports the frequency of the genetic variants. Variant coverage comparison between Ion PGM data (blue) and both Agilent (green) and Roche NimbleGen (red) data in non-exon (intron/downstream/upstream) regions reports a low coverage in both exome capture kits ( d ); rs839541 SNP was completely uncovered in Agilent libraries. Vertical axis displays coverage values in logarithmic scale

    Journal: BMC Cancer

    Article Title: Performance comparison of two commercial human whole-exome capture systems on formalin-fixed paraffin-embedded lung adenocarcinoma samples

    doi: 10.1186/s12885-016-2720-4

    Figure Lengend Snippet: Variant calling comparison between Ion PGM data and both WES systems. Variant calling comparison between Ion PGM data (blue) and both Agilent SureSelect (green) and Roche NimbleGen (red) data in exon regions shows 88 % of concordance (44/50) in both WES capture systems ( a ). Both systems failed to call 4 genetic variants (*) detected by Ion PGM platform at low frequencies (4-16 %). Further 4 variants were missed as follows: 2 by Agilent (COSM6225, rs80338963) and 2 by Roche NimbleGen (COSM40942, rs35775721). Horizontal axis reports the genetic variants (Additional file 3 : Table S8a) ordered from lowest to highest frequency (vertical axis) as assessed by Ion PGM platform. Variant coverage displays a quite similar trend between Agilent (green) and Roche NimbleGen (red) libraries, and is far lower than Ion PGM platform (blue) ( b ). Two Roche libraries report a low coverage in the uncalled variants (COSM40942, rs35775721). Vertical axis displays the variant coverage in logarithmic scale. Variant calling comparison between Ion PGM data (blue) and both Agilent (green) and Roche NimbleGen (red) data in non-exon regions shows a poor performance of both WES technologies ( c ). Both WES systems failed to call the rs839541 (*) SNP in ERBB4 gene, whereas rs1558544 SNP in EGFR was missed by all 10 Agilent libraries. Vertical axis reports the frequency of the genetic variants. Variant coverage comparison between Ion PGM data (blue) and both Agilent (green) and Roche NimbleGen (red) data in non-exon (intron/downstream/upstream) regions reports a low coverage in both exome capture kits ( d ); rs839541 SNP was completely uncovered in Agilent libraries. Vertical axis displays coverage values in logarithmic scale

    Article Snippet: Variant detection comparison between exome libraries prepared with both Agilent SureSelect and Roche NimbleGen kit.

    Techniques: Variant Assay

    Profiling off-target Cascade binding in a human exome (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a MiSeq chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).

    Journal: Cell

    Article Title: Massively parallel biophysical analysis of CRISPR-Cas complexes on next generation sequencing chips

    doi: 10.1016/j.cell.2017.05.044

    Figure Lengend Snippet: Profiling off-target Cascade binding in a human exome (A) The CHAMP-Exome analysis pipeline. Human genomic DNA is randomly sheared and enriched for exome sequences (blue) using standard oligonucleotide hybridization and bead pull-down protocols. After enrichment and adapter ligation, the exome is sequenced on a MiSeq chip, which is then used for CHAMP. Apparent Binding Affinities (ABAs) at each position in the exome were measured via CHAMP. (B) Maximum ABA values in each gene, ordered by rank. The dashed line indicates ABAs that fell outside of the experimentally defined cutoff for non-specific binding. Inset: histogram of genes that show measurable off-target binding. The gray zone indicates genes that had ABAs greater than 3 k B T . Red dots in (B) indicate three representative genes with strong off-target binding sites, further described in (C). (C) Example high-affinity peaks. ABA is measured at each position in each gene using all reads overlapping that position. A high-affinity site thus appears as a peak in ABA whose width is a function of the DNA shearing length distribution. Shown are the measured ABAs at each position in a few genes containing high-ABA peaks. The ABAs spanning each gene are shown in blue (left y-axis) and the sequencing coverage in purple (right y-axis). Exon boundaries are shown as the minor ticks along the x-axis, and cause sharp changes in displayed ABA and coverage values. (D) Sequence logo generated from a 210-bp window centered around each of the ABA peaks > 3 k B T ).

    Article Snippet: The exome library was then sequenced using the MiSeq Reagent Kit v3 (Illumina, 2×300 paired-end reads).

    Techniques: Binding Assay, Hybridization, Ligation, Chromatin Immunoprecipitation, Sequencing, Generated